Insulin-like growth factor regulates peak bone mineral density in mice by both growth hormone-dependent and -independent mechanisms. - Wikidata - awgldk - TriplyDB

Insulin-like growth factor regulates peak bone mineral density in mice by both growth hormone-dependent and -independent mechanisms.

Insulin-like growth factor regulates peak bone mineral density in mice by both growth hormone-dependent and -independent mechanisms.

http://www.wikidata.org/entity/Q34074077

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Role and Mechanisms of Actions of Thyroid Hormone on the Skeletal Development Lasting consequences of traumatic events on behavioral and skeletal parameters in a mouse model for post-traumatic stress disorder (PTSD).The COMT val158met polymorphism is associated with early pubertal development, height and cortical bone mass in girls.Disruption of insulin-like growth factor-I expression in type IIalphaI collagen-expressing cells reduces bone length and width in mice.IGF-I improved bone mineral density and body composition of weaver mutant mice.Stress and Alterations in Bones: An Interdisciplinary Perspective 25-hydroxyvitamin D, insulin-like growth factor-I, and bone mineral accrual during growth.Insulin-like growth factor-binding protein-5 induces a gender-related decrease in bone mineral density in transgenic mice Anti-steroidogenic factor ARR19 inhibits testicular steroidogenesis through the suppression of Nur77 transactivation.Mapping quantitative trait loci that influence serum insulin-like growth factor binding protein-5 levels in F2 mice (MRL/MpJ X SJL/J).Conditional deletion of insulin-like growth factor-I in collagen type 1alpha2-expressing cells results in postnatal lethality and a dramatic reduction in bone accretion Evidence that sensitivity to growth hormone (GH) is growth period and tissue type dependent: studies in GH-deficient lit/lit mice.Impaired skeletal growth in mice with haploinsufficiency of IGF-I: genetic evidence that differences in IGF-I expression could contribute to peak bone mineral density differences.The multi-functional role of insulin-like growth factor binding proteins in bone.Whole genome microarray analysis of growth hormone-induced gene expression in bone: T-box3, a novel transcription factor, regulates osteoblast proliferation.Sex steroid actions in male bone The role of GH/IGF-I-mediated mechanisms in sex differences in cortical bone size in mice Serum IGF-1 affects skeletal acquisition in a temporal and compartment-specific manner.The negative impact of single prolonged stress (SPS) on bone development in mice.Osteocyte-derived insulin-like growth factor I is not essential for the bone repletion response in mice The negative impact of traumatic brain injury (TBI) on bone in a mouse model.Elevated serum levels of IGF-1 are sufficient to establish normal body size and skeletal properties even in the absence of tissue IGF-1.Growth hormone regulates the balance between bone formation and bone marrow adiposity.Insulin-like growth factor (IGF)-I and IGF-II contribute differentially to the phenotype of pregnancy associated plasma protein-A knock-out mice.Osteoblast-restricted Disruption of the Growth Hormone Receptor in Mice Results in Sexually Dimorphic Skeletal Phenotypes.Microarchitecture, but not bone mechanical properties, is rescued with growth hormone treatment in a mouse model of growth hormone deficiency Prader-Willi Critical Region, a Non-Translated, Imprinted Central Regulator of Bone Mass: Possible Role in Skeletal Abnormalities in Prader-Willi Syndrome.Weak Epistasis Generally Stabilizes Phenotypes in a Mouse Intercross.Genetic evidence that thyroid hormone is indispensable for prepubertal insulin-like growth factor-I expression and bone acquisition in mice.Restricted growth and insulin-like growth factor-1 deficiency in mice lacking presenilin-1 in the neural crest cell lineage.SIRT6 deficiency culminates in low-turnover osteopenia.Effects of alcohol on skeletal response to growth hormone in hypophysectomized rats.Regulation of skeletal growth and mineral acquisition by the GH/IGF-1 axis: Lessons from mouse models.High bone mineral density and fracture risk in type 2 diabetes as skeletal complications of inadequate glucose control: the Rotterdam Study Prepubertal OVX increases IGF-I expression and bone accretion in C57BL/6J mice.The role of liver-derived insulin-like growth factor-I.The new frontier of bone formation: a breakthrough in postmenopausal osteoporosis?Growth hormone: does it have a therapeutic role in fracture healing?Role of Osteocyte-derived Insulin-Like Growth Factor I in Developmental Growth, Modeling, Remodeling, and Regeneration of the Bone.PAPP-A: a promising therapeutic target for healthy longevity.

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Insulin-like growth factor regulates peak bone mineral density in mice by both growth hormone-dependent and -independent mechanisms.

http://www.wikidata.org/entity/Q34074077

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2003 nî lūn-bûn

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2003 թվականի մարտին հրատարակված գիտական հոդված

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2003年の論文

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Insulin-like growth factor reg ...... t and -independent mechanisms.

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Insulin-like growth factor reg ...... t and -independent mechanisms.

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Insulin-like growth factor reg ...... t and -independent mechanisms.

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Insulin-like growth factor reg ...... t and -independent mechanisms.

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Insulin-like growth factor reg ...... t and -independent mechanisms.

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Insulin-like growth factor reg ...... t and -independent mechanisms.

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Insulin-like growth factor reg ...... t and -independent mechanisms.

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Insulin-like growth factor reg ...... t and -independent mechanisms.

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Insulin-like growth factor reg ...... t and -independent mechanisms.

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Charmaine Richman

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David J Baylink

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Jon Wergedal

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Leah Rea Donahue

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Rongqing Guo

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Subburaman Mohan

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Yousef Amaar

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P2860

Growth hormone deficiency in 'little' mice results in aberrant body composition, reduced insulin-like growth factor-I and insulin-like growth factor-binding protein-3 (IGFBP-3), but does not affect IGFBP-2, -1 or -4

GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function

Role of insulin-like growth factors in embryonic and postnatal growth

Disproportional skeletal growth and markedly decreased bone mineral content in growth hormone receptor -/- mice.

Effect of insulin-like growth factor-1 (IGF-1) plus alendronate on bone density during puberty in IGF-1-deficient MIDI mice.

Genetics of osteoporosis.

Growth hormone axis overview--somatomedin hypothesis.

Changes in vertebral bone density in black girls and white girls during childhood and puberty.

In vitro studies of insulin-like growth factor I and bone.

The worldwide problem of osteoporosis: insights afforded by epidemiology.

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929-936

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10.1210/EN.2002-220948

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