Immunosuppressive effects of tautomycetin in vivo and in vitro via T cell-specific apoptosis induction
about
Biochemical and Structural Characterization of the Tautomycetin Thioesterase: Analysis of a Stereoselective Polyketide HydrolaseCharacterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.Functional characterization of TtnD and TtnF, unveiling new insights into tautomycetin biosynthesis.The synergistic effect of Tautomycetin on Cyclosporine A-mediated immunosuppression in a rodent islet allograft model.The double-stranded RNA-dependent protein kinase differentially regulates insulin receptor substrates 1 and 2 in HepG2 cellsFunctional characterization of ttnI completing the tailoring steps for tautomycetin biosynthesis in Streptomyces griseochromogenesCharacterization of the tautomycetin biosynthetic gene cluster from Streptomyces griseochromogenes provides new insight into dialkylmaleic anhydride biosynthesis.SHP2 is a target of the immunosuppressant tautomycetin.Effector mechanisms in transplant rejection.Differential effects of tautomycetin and its derivatives on protein phosphatase inhibition, immunosuppressive function and antitumor activity.Precise cloning and tandem integration of large polyketide biosynthetic gene cluster using Streptomyces artificial chromosome system.Identification and biotechnological application of novel regulatory genes involved in Streptomyces polyketide overproduction through reverse engineering strategy.Tautomycin suppresses growth and neuroendocrine hormone markers in carcinoid cells through activation of the Raf-1 pathwayThe phosphoprotein phosphatase family of Ser/Thr phosphatases as principal targets of naturally occurring toxins.Targeting protein tyrosine phosphatase SHP2 for therapeutic intervention.Biosynthesis, regulation, and engineering of a linear polyketide tautomycetin: a novel immunosuppressant in Streptomyces sp. CK4412.Biological activities of an engineered tautomycetin analogue via disruption of tmcR-encoding hydroxylase in Streptomyces sp. CK4412.
P2860
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P2860
Immunosuppressive effects of tautomycetin in vivo and in vitro via T cell-specific apoptosis induction
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Immunosuppressive effects of t ...... l-specific apoptosis induction
@ast
Immunosuppressive effects of t ...... l-specific apoptosis induction
@en
Immunosuppressive effects of t ...... l-specific apoptosis induction
@nl
type
label
Immunosuppressive effects of t ...... l-specific apoptosis induction
@ast
Immunosuppressive effects of t ...... l-specific apoptosis induction
@en
Immunosuppressive effects of t ...... l-specific apoptosis induction
@nl
prefLabel
Immunosuppressive effects of t ...... l-specific apoptosis induction
@ast
Immunosuppressive effects of t ...... l-specific apoptosis induction
@en
Immunosuppressive effects of t ...... l-specific apoptosis induction
@nl
P2093
P2860
P356
P1476
Immunosuppressive effects of t ...... l-specific apoptosis induction
@en
P2093
Alfred Bothwell
Duck-Jong Han
Eun-Ju Chang
Heung-Kyu Lee
Jae-Hyuck Shim
Jin-Hwan Han
Jung-Jin Yang
Sang-Kyou Lee
Tomohiro Morio
Wook-Jin Chae
P2860
P304
10617-10622
P356
10.1073/PNAS.162522099
P407
P577
2002-07-29T00:00:00Z