SHP2 is a target of the immunosuppressant tautomycetin.

SHP2 is a target of the immunosuppressant tautomycetin.

Item
http://www.wikidata.org/entity/Q34554631
Small molecule tools for functional interrogation of protein tyrosine phosphatasesTherapeutic potential of targeting the oncogenic SHP2 phosphatase.Functional characterization of ttnI completing the tailoring steps for tautomycetin biosynthesis in Streptomyces griseochromogenesInhibition of Shp2 suppresses mutant EGFR-induced lung tumors in transgenic mouse model of lung adenocarcinoma.Differential effects of tautomycetin and its derivatives on protein phosphatase inhibition, immunosuppressive function and antitumor activity.Precise cloning and tandem integration of large polyketide biosynthetic gene cluster using Streptomyces artificial chromosome system.Discovery of a Novel Inhibitor of the Protein Tyrosine Phosphatase Shp2.Protein tyrosine phosphatase SHP2 regulates TGF-β1 production in airway epithelia and asthmatic airway remodeling in mice.Targeting protein tyrosine phosphatase SHP2 for therapeutic intervention.Biosynthesis, regulation, and engineering of a linear polyketide tautomycetin: a novel immunosuppressant in Streptomyces sp. CK4412.Covalent inhibition of protein tyrosine phosphatases.Biological activities of an engineered tautomycetin analogue via disruption of tmcR-encoding hydroxylase in Streptomyces sp. CK4412.PP1:Tautomycetin Complex Reveals a Path toward the Development of PP1-Specific Inhibitors.
P2860

SHP2 is a target of the immunosuppressant tautomycetin.

Item
http://www.wikidata.org/entity/Q34554631
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
SHP2 is a target of the immunosuppressant tautomycetin.
@ast
SHP2 is a target of the immunosuppressant tautomycetin.
@en
SHP2 is a target of the immunosuppressant tautomycetin.
@nl
type
label
SHP2 is a target of the immunosuppressant tautomycetin.
@ast
SHP2 is a target of the immunosuppressant tautomycetin.
@en
SHP2 is a target of the immunosuppressant tautomycetin.
@nl
prefLabel
SHP2 is a target of the immunosuppressant tautomycetin.
@ast
SHP2 is a target of the immunosuppressant tautomycetin.
@en
SHP2 is a target of the immunosuppressant tautomycetin.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
SHP2 is a target of the immunosuppressant tautomycetin.
@en
P2093
P2860
P304
P31
P356
10.1016/J.CHEMBIOL.2010.10.015
P433
P478
P577
P5875
P698
P921
P932