Identification of 5' AMP-activated kinase as a target of reactive aldehydes during chronic ingestion of high concentrations of ethanol.
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4-Hydroxy-nonenal-A Bioactive Lipid Peroxidation ProductMitochondrial dysfunction and tissue injury by alcohol, high fat, nonalcoholic substances and pathological conditions through post-translational protein modificationsProtein lipoxidation: Detection strategies and challengesIncreased 4-hydroxynonenal protein adducts in male GSTA4-4/PPAR-α double knockout mice enhance injury during early stages of alcoholic liver disease.The lipid peroxidation product 4-hydroxy-trans-2-nonenal causes protein synthesis in cardiac myocytes via activated mTORC1-p70S6K-RPS6 signaling.BDNF-TrkB pathway mediates neuroprotection of hydrogen sulfide against formaldehyde-induced toxicity to PC12 cells.Chronic ethanol consumption induces mitochondrial protein acetylation and oxidative stress in the kidneyLiver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular DamageIncreased hepatocellular protein carbonylation in human end-stage alcoholic cirrhosisHydrogen Sulfide Protects against Chronic Unpredictable Mild Stress-Induced Oxidative Stress in Hippocampus by Upregulation of BDNF-TrkB Pathway.The role of lipin-1 in the pathogenesis of alcoholic fatty liver.Host homeostatic responses to alcohol-induced cellular stress in animal models of alcoholic liver disease.Signaling by 4-hydroxy-2-nonenal: Exposure protocols, target selectivity and degradation.Nocturnal hypoxia-induced oxidative stress promotes progression of pediatric non-alcoholic fatty liver diseaseAMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages.Deletion of GSTA4-4 results in increased mitochondrial post-translational modification of proteins by reactive aldehydes following chronic ethanol consumption in mice.Steatosis-induced proteins adducts with lipid peroxidation products and nuclear electrophilic stress in hepatocytes.Alda-1 Protects Against Acrolein-Induced Acute Lung Injury and Endothelial Barrier Dysfunction.Dysregulation of antioxidant responses in patients diagnosed with concomitant Primary Sclerosing Cholangitis/Inflammatory Bowel Disease.Differential carbonylation of proteins in end-stage human fatty and nonfatty NASH.Elevated Nrf-2 responses are insufficient to mitigate protein carbonylation in hepatospecific PTEN deletion mice.
P2860
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P2860
Identification of 5' AMP-activated kinase as a target of reactive aldehydes during chronic ingestion of high concentrations of ethanol.
description
2014 nî lūn-bûn
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2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2014 թվականի ապրիլին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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name
Identification of 5' AMP-activ ...... igh concentrations of ethanol.
@ast
Identification of 5' AMP-activ ...... igh concentrations of ethanol.
@en
Identification of 5' AMP-activ ...... igh concentrations of ethanol.
@nl
type
label
Identification of 5' AMP-activ ...... igh concentrations of ethanol.
@ast
Identification of 5' AMP-activ ...... igh concentrations of ethanol.
@en
Identification of 5' AMP-activ ...... igh concentrations of ethanol.
@nl
prefLabel
Identification of 5' AMP-activ ...... igh concentrations of ethanol.
@ast
Identification of 5' AMP-activ ...... igh concentrations of ethanol.
@en
Identification of 5' AMP-activ ...... igh concentrations of ethanol.
@nl
P2093
P2860
P356
P1476
Identification of 5' AMP-activ ...... igh concentrations of ethanol.
@en
P2093
Colin T Shearn
David J Orlicky
Dennis R Petersen
Rebecca L Smathers-McCullough
P2860
P304
15449-15462
P356
10.1074/JBC.M113.543942
P407
P577
2014-04-10T00:00:00Z