In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia. - Wikidata - awgldk - TriplyDB

In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia.

In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia.

http://www.wikidata.org/entity/Q34078726

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PI3K Signaling in Normal B Cells and Chronic Lymphocytic Leukemia (CLL)The pathogenesis of chronic lymphocytic leukemia Clonal evolution in hematological malignancies and therapeutic implications Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities.The pathogenic relevance of the prognostic markers CD38 and CD49d in chronic lymphocytic leukemia Direct in vivo evidence for increased proliferation of CLL cells in lymph nodes compared to bone marrow and peripheral blood.Leukemia-cell proliferation and disease progression in patients with early stage chronic lymphocytic leukemia.In vivo kinetics and nonradioactive imaging of rapidly proliferating cells in graft-versus-host disease Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765.The MEC1 and MEC2 lines represent two CLL subclones in different stages of progression towards prolymphocytic leukemia.Ibrutinib-induced lymphocytosis in patients with chronic lymphocytic leukemia: correlative analyses from a phase II study.A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease.TLR-9 and IL-15 Synergy Promotes the In Vitro Clonal Expansion of Chronic Lymphocytic Leukemia B Cells.Intraclonal complexity in chronic lymphocytic leukemia: fractions enriched in recently born/divided and older/quiescent cells.Stromal endothelial cells establish a bidirectional crosstalk with chronic lymphocytic leukemia cells through the TNF-related factors BAFF, APRIL, and CD40L.IGHV-unmutated and IGHV-mutated chronic lymphocytic leukemia cells produce activation-induced deaminase protein with a full range of biologic functions Inter- and intra-patient clonal and subclonal heterogeneity of chronic lymphocytic leukaemia: evidences from circulating and lymph nodal compartments.CD38 and chronic lymphocytic leukemia: a decade later.Autoantigen can promote progression to a more aggressive TCL1 leukemia by selecting variants with enhanced B-cell receptor signaling BTK inhibition results in impaired CXCR4 chemokine receptor surface expression, signaling and function in chronic lymphocytic leukemia.Massive and parallel expression profiling using microarrayed single-cell sequencing.Chronic lymphocytic leukaemia: a disease of activated monoclonal B cells.Coming full circle: 70 years of chronic lymphocytic leukemia cell redistribution, from glucocorticoids to inhibitors of B-cell receptor signaling Microenvironment interactions and B-cell receptor signaling in Chronic Lymphocytic Leukemia: Implications for disease pathogenesis and treatment.Functional proteomic insights in B-cell chronic lymphocytic leukemia.Epigenetic regulation of WNT signaling in chronic lymphocytic leukemia.p53 and cell cycle independent dysregulation of autophagy in chronic lymphocytic leukaemia Metformin inhibits cell cycle progression of B-cell chronic lymphocytic leukemia cells.Common nonmutational NOTCH1 activation in chronic lymphocytic leukemia.Inflammation, the microenvironment and chronic lymphocytic leukemia.CD38 signals upregulate expression and functions of matrix metalloproteinase-9 in chronic lymphocytic leukemia cells.Combined BTK and PI3Kδ Inhibition with Acalabrutinib and ACP-319 Improves Survival and Tumor Control in CLL Mouse Model.Delineating the distinct role of AKT in mediating cell survival and proliferation induced by CD154 and IL-4/IL-21 in chronic lymphocytic leukemia.In-vitro and in-vivo evidence for uncoupling of BCR internalization and signaling in chronic lymphocytic leukemia.Targeting the Adenosinergic Axis in Chronic Lymphocytic Leukemia: A Way to Disrupt the Tumor Niche?CD38 increases CXCL12-mediated signals and homing of chronic lymphocytic leukemia cells.Relevance of P-glycoprotein on CXCR4+ B cells to organ manifestation in highly active rheumatoid arthritis.N-(4-hydroxyphenyl)retinamide promotes apoptosis of resting and proliferating B-cell chronic lymphocytic leukemia cells and potentiates fludarabine and ABT-737 cytotoxicity.The times they are a-changin': prognostic markers in the new era of BCR-targeting therapies for CLL.FcγRIIb expression in early stage chronic lymphocytic leukemia.

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P2860

In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia.

http://www.wikidata.org/entity/Q34078726

description

2009 nî lūn-bûn

@nan

2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

In vivo intraclonal and interc ...... chronic lymphocytic leukemia.

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In vivo intraclonal and interc ...... chronic lymphocytic leukemia.

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In vivo intraclonal and interc ...... chronic lymphocytic leukemia.

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type

label

In vivo intraclonal and interc ...... chronic lymphocytic leukemia.

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In vivo intraclonal and interc ...... chronic lymphocytic leukemia.

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In vivo intraclonal and interc ...... chronic lymphocytic leukemia.

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prefLabel

In vivo intraclonal and interc ...... chronic lymphocytic leukemia.

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In vivo intraclonal and interc ...... chronic lymphocytic leukemia.

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In vivo intraclonal and interc ...... chronic lymphocytic leukemia.

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BLOOD-2009-05-219634

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In vivo intraclonal and interc ...... chronic lymphocytic leukemia.

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Carlo Calissano

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Carol Moreno

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Cristina Sison

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Elizabeth J Murphy

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Gregory Hayes

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Jonathan E Kolitz

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Kanti R Rai

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Marc K Hellerstein

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Matthew S Kaufman

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Nicholas Chiorazzi

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P2860

CD38 and CD100 lead a network of surface receptors relaying positive signals for B-CLL growth and survival

A chemokine-driven positive feedback loop organizes lymphoid follicles

Chronic lymphocytic leukemia

Human CD38, a leukocyte receptor and ectoenzyme, is a member of a novel eukaryotic gene family of nicotinamide adenine dinucleotide+-converting enzymes: extensive structural homology with the genes for murine bone marrow stromal cell antigen 1 and a

Chemokines and cell migration in secondary lymphoid organs.

In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells

Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia.

Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia.

The indispensable role of microenvironment in the natural history of low-grade B-cell neoplasms.

CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease.

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4832-4842

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scholarly article

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10.1182/BLOOD-2009-05-219634

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23

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19789386

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2925477

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