A small molecule p75NTR ligand, LM11A-31, reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression.
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Neurotrophic factor small-molecule mimetics mediated neuroregeneration and synaptic repair: emerging therapeutic modality for Alzheimer's diseaseA small molecule p75NTR ligand normalizes signalling and reduces Huntington's disease phenotypes in R6/2 and BACHD mice.Neuroregeneration versus neurodegeneration: toward a paradigm shift in Alzheimer's disease drug discovery.[18F]GE-180 PET Detects Reduced Microglia Activation After LM11A-31 Therapy in a Mouse Model of Alzheimer's Disease.Increased Hippocampal ProBDNF Contributes to Memory Impairments in Aged Mice.Implication of the neurotrophin receptor p75NTR in vascular diseases: beyond the eye.Polygalae Radix Extract Prevents Axonal Degeneration and Memory Deficits in a Transgenic Mouse Model of Alzheimer's Disease.Modulating Neurotrophin Receptor Signaling as a Therapeutic Strategy for Huntington's Disease.Targeting the intracellular signaling "STOP" and "GO" pathways for the treatment of alcohol use disorders.Alzheimer's associated amyloid and tau deposition co-localizes with a homeostatic myelin repair pathway in two mouse models of post-stroke mixed dementia
P2860
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P2860
A small molecule p75NTR ligand, LM11A-31, reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression.
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
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2014年论文
@wuu
name
A small molecule p75NTR ligand ...... ate-stage disease progression.
@ast
A small molecule p75NTR ligand ...... ate-stage disease progression.
@en
A small molecule p75NTR ligand ...... ate-stage disease progression.
@nl
type
label
A small molecule p75NTR ligand ...... ate-stage disease progression.
@ast
A small molecule p75NTR ligand ...... ate-stage disease progression.
@en
A small molecule p75NTR ligand ...... ate-stage disease progression.
@nl
prefLabel
A small molecule p75NTR ligand ...... ate-stage disease progression.
@ast
A small molecule p75NTR ligand ...... ate-stage disease progression.
@en
A small molecule p75NTR ligand ...... ate-stage disease progression.
@nl
P2093
P2860
P1433
P1476
A small molecule p75NTR ligand ...... ate-stage disease progression.
@en
P2093
Carly Finkle
Danielle A Simmons
Frank M Longo
Juliet K Knowles
Nadia P Belichenko
Stephen M Massa
P2860
P304
P356
10.1371/JOURNAL.PONE.0102136
P407
P577
2014-08-25T00:00:00Z