Small, nonpeptide p75NTR ligands induce survival signaling and inhibit proNGF-induced death. - Wikidata - awgldk - TriplyDB

Small, nonpeptide p75NTR ligands induce survival signaling and inhibit proNGF-induced death.

Small, nonpeptide p75NTR ligands induce survival signaling and inhibit proNGF-induced death.

http://www.wikidata.org/entity/Q33243843

about

A small molecule p75(NTR) ligand protects neurogenesis after traumatic brain injury Chronic and acute models of retinal neurodegeneration TrkA activity are neuroprotective whereas p75NTR activity is neurotoxic through a paracrine mechanism Molecular evolution of the vertebrate mechanosensory cell and ear Small molecule p75NTR ligands reduce pathological phosphorylation and misfolding of tau, inflammatory changes, cholinergic degeneration, and cognitive deficits in AβPP(L/S) transgenic mice.A data-driven approach for evaluating multi-modal therapy in traumatic brain injury.Small molecule, non-peptide p75 ligands inhibit Abeta-induced neurodegeneration and synaptic impairment.Small molecule activators of the Trk receptors for neuroprotection Bivalent peptidomimetic ligands of TrkC are biased agonists and selectively induce neuritogenesis or potentiate neurotrophin-3 trophic signals A small molecule p75NTR ligand normalizes signalling and reduces Huntington's disease phenotypes in R6/2 and BACHD mice.The p75 neurotrophin receptor is expressed by adult mouse dentate progenitor cells and regulates neuronal and non-neuronal cell genesis.Dual-Component Gelatinous Peptide/Reactive Oligomer Formulations as Conduit Material and Luminal Filler for Peripheral Nerve Regeneration.NGF and proNGF regulate functionally distinct mRNAs in PC12 cells: an early gene expression profiling.Acute administration of the small-molecule p75(NTR) ligand does not prevent hippocampal neuron loss or development of spontaneous seizures after pilocarpine-induced status epilepticus A small molecule p75NTR ligand, LM11A-31, reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression.Understanding proneurotrophin actions: Recent advances and challenges.Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents.CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma.Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease.BNN27, a 17-Spiroepoxy Steroid Derivative, Interacts With and Activates p75 Neurotrophin Receptor, Rescuing Cerebellar Granule Neurons from Apoptosis.Anti-cancer drug induced neurotoxicity and identification of Rho pathway signaling modulators as potential neuroprotectants.Amelioration of cisplatin-induced experimental peripheral neuropathy by a small molecule targeting p75 NTR Association of p75(NTR) and α9β1 integrin modulates NGF-dependent cellular responses.Potential Effect of CD271 on Human Mesenchymal Stromal Cell Proliferation and Differentiation.Novel p75 neurotrophin receptor ligand stabilizes neuronal calcium, preserves mitochondrial movement and protects against HIV associated neuropathogenesis Oral administration of a small molecule targeted to block proNGF binding to p75 promotes myelin sparing and functional recovery after spinal cord injury.The Neurotrophic Factor Receptor p75 in the Rat Dorsolateral Striatum Drives Excessive Alcohol Drinking Signaling through Rho GTPase pathway as viable drug target.Time-Dependent Nerve Growth Factor Signaling Changes in the Rat Retina During Optic Nerve Crush-Induced Degeneration of Retinal Ganglion Cells.Astrogliosis in amyotrophic lateral sclerosis: role and therapeutic potential of astrocytes Dynamic nature of the p75 neurotrophin receptor in response to injury and disease From demyelination to remyelination: the road toward therapies for spinal cord injury.Neuroregeneration versus neurodegeneration: toward a paradigm shift in Alzheimer's disease drug discovery.PROneurotrophins and CONSequences.[18F]GE-180 PET Detects Reduced Microglia Activation After LM11A-31 Therapy in a Mouse Model of Alzheimer's Disease.Motoneuron programmed cell death in response to proBDNF.Commentary: Regulating proNGF action: multiple targets for therapeutic intervention ProNGF-p75NTR axis plays a proinflammatory role in inflamed joints: a novel pathogenic mechanism in chronic arthritis.Modulating Neurotrophin Receptor Signaling as a Therapeutic Strategy for Huntington's Disease.Role of proNGF/p75 signaling in bladder dysfunction after spinal cord injury.

P2860

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P2860

Small, nonpeptide p75NTR ligands induce survival signaling and inhibit proNGF-induced death.

http://www.wikidata.org/entity/Q33243843

description

2006 nî lūn-bûn

@nan

2006 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի մայիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

@wuu

name

Small, nonpeptide p75NTR ligan ...... inhibit proNGF-induced death.

@ast

Small, nonpeptide p75NTR ligan ...... inhibit proNGF-induced death.

@en

type

label

Small, nonpeptide p75NTR ligan ...... inhibit proNGF-induced death.

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Small, nonpeptide p75NTR ligan ...... inhibit proNGF-induced death.

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prefLabel

Small, nonpeptide p75NTR ligan ...... inhibit proNGF-induced death.

@ast

Small, nonpeptide p75NTR ligan ...... inhibit proNGF-induced death.

@en

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JNEUROSCI.3547-05.2006

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Journal of Neuroscience

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Small, nonpeptide p75NTR ligan ...... d inhibit proNGF-induced death

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P2093

Anthony W Harrington

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Barbara L Hempstead

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Frank M Longo

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Laura A Moore

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Mi Lyang Kim

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Rosemary Kraemer

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Stephen M Massa

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Sung Ok Yoon

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Tao Yang

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Youmei Xie

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5288-5300

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scholarly article

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10.1523/JNEUROSCI.3547-05.2006

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