Characterization of the lipid binding properties of Otoferlin reveals specific interactions between PI(4,5)P2 and the C2C and C2F domains.

Characterization of the lipid binding properties of Otoferlin reveals specific interactions between PI(4,5)P2 and the C2C and C2F domains.

Item
http://www.wikidata.org/entity/Q34089077
A novel missense mutation in the C2C domain of otoferlin causes profound hearing impairment in an Omani family with auditory neuropathy.Extended synaptotagmins (E-Syts): Architecture and dynamics of membrane contact sites revealed.A Five-Gene Signature Predicts Prognosis in Patients with Kidney Renal Clear Cell CarcinomaAuditory neuropathy--neural and synaptic mechanisms.Ferlins Show Tissue-Specific Expression and Segregate as Plasma Membrane/Late Endosomal or Trans-Golgi/Recycling Ferlins.Dysferlin Binds SNAREs (Soluble N-Ethylmaleimide-sensitive Factor (NSF) Attachment Protein Receptors) and Stimulates Membrane Fusion in a Calcium-sensitive Manner.Activity-Dependent Phosphorylation by CaMKIIδ Alters the Ca2+ Affinity of the Multi-C2-Domain Protein Otoferlin.Hair Cell Transduction, Tuning, and Synaptic Transmission in the Mammalian Cochlea.Emerging Functional Differences between the Synaptotagmin and Ferlin Calcium Sensor Families.Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses.Otoferlin is a multivalent calcium-sensitive scaffold linking SNAREs and calcium channels.
P2860

Characterization of the lipid binding properties of Otoferlin reveals specific interactions between PI(4,5)P2 and the C2C and C2F domains.

Item
http://www.wikidata.org/entity/Q34089077
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Characterization of the lipid ...... 2 and the C2C and C2F domains.
@ast
Characterization of the lipid ...... 2 and the C2C and C2F domains.
@en
Characterization of the lipid ...... 2 and the C2C and C2F domains.
@nl
type
label
Characterization of the lipid ...... 2 and the C2C and C2F domains.
@ast
Characterization of the lipid ...... 2 and the C2C and C2F domains.
@en
Characterization of the lipid ...... 2 and the C2C and C2F domains.
@nl
prefLabel
Characterization of the lipid ...... 2 and the C2C and C2F domains.
@ast
Characterization of the lipid ...... 2 and the C2C and C2F domains.
@en
Characterization of the lipid ...... 2 and the C2C and C2F domains.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Characterization of the lipid ...... 2 and the C2C and C2F domains.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932