The association of PNPLA3 variants with liver enzymes in childhood obesity is driven by the interaction with abdominal fat.
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Genetic Factors in the Pathogenesis of Nonalcoholic Fatty Liver and SteatohepatitisPediatric fatty liver disease: role of ethnicity and geneticsAssociation between liver-specific gene polymorphisms and their expression levels with nonalcoholic fatty liver diseasePhysical activity and sedentary behavior can modulate the effect of the PNPLA3 variant on childhood NAFLD: a case-control study in a Chinese population.Understanding the pathophysiological mechanisms in the pediatric non-alcoholic fatty liver disease: The role of genetics.Pediatric non-alcoholic fatty liver disease: New insights and future directionsThe Association between Pediatric NAFLD and Common Genetic Variants.Commentary: dissecting the PNPLA3 association with liver fat and stiffness, and interaction with diet.Crystal structure of patatin-17 in complex with aged and non-aged organophosphorus compounds.Insulin resistance and steatosis in HBV-HCV co-infected patients: Role of PNPLA3 polymorphisms and impact on liver fibrosis progressionHepatic fat accumulation is modulated by the interaction between the rs738409 variant in the PNPLA3 gene and the dietary omega6/omega3 PUFA intakeParadoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant.Cannabinoid receptor type 2 functional variant influences liver damage in children with non-alcoholic fatty liver disease.Genetic variant I148M in PNPLA3 is associated with the ultrasonography-determined steatosis degree in a Chinese populationGenetic variants in PNPLA3 and risk of non-alcoholic fatty liver disease in a Han Chinese population.Linked PNPLA3 polymorphisms confer susceptibility to nonalcoholic steatohepatitis and decreased viral load in chronic hepatitis B.PNPLA3 I148M Variant Influences Circulating Retinol in Adults with Nonalcoholic Fatty Liver Disease or Obesity.Calcium-independent phospholipases A2 and their roles in biological processes and diseases.Oxidized metabolites of linoleic acid as biomarkers of liver injury in nonalcoholic steatohepatitis.PNPLA3 148M Carriers with Inflammatory Bowel Diseases Have Higher Susceptibility to Hepatic Steatosis and Higher Liver Enzymes.Insights from Genome-Wide Association Analyses of Nonalcoholic Fatty Liver Disease.PNPLA3 I148M polymorphism and progressive liver disease.Metabolic syndrome in children (Review).Genetic predisposition in NAFLD and NASH: impact on severity of liver disease and response to treatment.The PNPLA3 Ile148Met interacts with overweight and dietary intakes on fasting triglyceride levelsOmega-3 fatty acids: Mechanisms of benefit and therapeutic effects in pediatric and adult NAFLD.TM6SF2 Glu167Lys polymorphism is associated with low levels of LDL-cholesterol and increased liver injury in obese children.Abdominal fat interacts with PNPLA3 I148M, but not with the APOC3 variant in the pathogenesis of liver steatosis in chronic hepatitis C.Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci.The Frequent Adiponutrin (PNPLA3) Variant p.Ile148Met Is Associated with Early Liver Injury: Analysis of a German Pediatric Cohort.PNPLA3 I148M polymorphism is associated with elevated alanine transaminase levels in Mexican Indigenous and Mestizo populations.Patatin-like phospholipase domain-containing 3 I148M affects liver steatosis in patients with chronic hepatitis B.The Genetics of Pediatric Nonalcoholic Fatty Liver Disease.Associations of I148M variant in PNPLA3 gene with plasma ALT levels during 2-year follow-up in normal weight and overweight children: the PANIC Study.Patatin-like phospholipase domain-containing protein 3 promotes transfer of essential fatty acids from triglycerides to phospholipids in hepatic lipid droplets.Meta-analysis reveals a specific association of the PNPLA3 I148M polymorphism with ALT level in adolescents.
P2860
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P2860
The association of PNPLA3 variants with liver enzymes in childhood obesity is driven by the interaction with abdominal fat.
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The association of PNPLA3 vari ...... nteraction with abdominal fat.
@ast
The association of PNPLA3 vari ...... nteraction with abdominal fat.
@en
The association of PNPLA3 vari ...... nteraction with abdominal fat.
@nl
type
label
The association of PNPLA3 vari ...... nteraction with abdominal fat.
@ast
The association of PNPLA3 vari ...... nteraction with abdominal fat.
@en
The association of PNPLA3 vari ...... nteraction with abdominal fat.
@nl
prefLabel
The association of PNPLA3 vari ...... nteraction with abdominal fat.
@ast
The association of PNPLA3 vari ...... nteraction with abdominal fat.
@en
The association of PNPLA3 vari ...... nteraction with abdominal fat.
@nl
P2093
P2860
P50
P1433
P1476
The association of PNPLA3 vari ...... nteraction with abdominal fat.
@en
P2093
Alessandra Amato
Carmine Brienza
Emanuele Miraglia del Giudice
Grazia Cirillo
Piera Savarese
P2860
P304
P356
10.1371/JOURNAL.PONE.0027933
P407
P577
2011-11-28T00:00:00Z