PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease. - Wikidata - awgldk - TriplyDB

PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease.

PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease.

http://www.wikidata.org/entity/Q34759018

about

Non-alcoholic fatty liver disease: what the clinician needs to know.Nonalcoholic fatty liver disease: a comprehensive review of a growing epidemic Type 2 Diabetes in Non-Alcoholic Fatty Liver Disease and Hepatitis C Virus Infection--Liver: The "Musketeer" in the Spotlight Genetic background in nonalcoholic fatty liver disease: A comprehensive review Genetic Factors in the Pathogenesis of Nonalcoholic Fatty Liver and Steatohepatitis Impact of IL28B, ITPA and PNPLA3 genetic variants on therapeutic outcome and progression of hepatitis C virus infection Composite prognostic models across the non-alcoholic fatty liver disease spectrum: Clinical application in developing countries Non-alcoholic fatty liver disease and diabetes: from physiopathological interplay to diagnosis and treatment Pediatric fatty liver disease: role of ethnicity and genetics Molecular Pathogenesis of NASH Glucokinase regulatory protein gene polymorphism affects liver fibrosis in non-alcoholic fatty liver disease The PNPLA3 rs738409 G-allele associates with reduced fasting serum triglyceride and serum cholesterol in Danes with impaired glucose regulation Association between liver-specific gene polymorphisms and their expression levels with nonalcoholic fatty liver disease Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease.Mechanisms for insulin resistance: common threads and missing links Nonalcoholic Fatty Liver Disease: Pathophysiology and Management.Omic studies reveal the pathogenic lipid droplet proteins in non-alcoholic fatty liver disease.Heritability of Hepatic Fibrosis and Steatosis Based on a Prospective Twin Study Non-invasive Testing for NASH and NASH with Advanced Fibrosis: Are We There Yet?Noninvasive fatty liver markers predict liver disease mortality in the U.S. population.A multi-component classifier for nonalcoholic fatty liver disease (NAFLD) based on genomic, proteomic, and phenomic data domains.Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease.The Association between Pediatric NAFLD and Common Genetic Variants.Pooled genetic analysis in ultrasound measured non-alcoholic fatty liver disease in Indian subjects: A pilot study.Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.Nonalcoholic fatty liver disease and the heart in children and adolescents.The PNPLA3 rs738409 148M/M genotype is a risk factor for liver cancer in alcoholic cirrhosis but shows no or weak association in hepatitis C cirrhosis.The association of PNPLA3 variants with liver enzymes in childhood obesity is driven by the interaction with abdominal fat.Genetic variation I148M in patatin-like phospholipase 3 gene and risk of non-alcoholic fatty liver disease among Filipinos.Association between the PNPLA3 I148M polymorphism and non-alcoholic fatty liver disease in the Uygur and Han ethnic groups of northwestern China.Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant.PNPLA 3 I148M genetic variant associates with insulin resistance and baseline viral load in HCV genotype 2 but not in genotype 3 infection Genetic variant I148M in PNPLA3 is associated with the ultrasonography-determined steatosis degree in a Chinese population Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome.Genetic variants in PNPLA3 and risk of non-alcoholic fatty liver disease in a Han Chinese population.Lipoprotein subclass metabolism in nonalcoholic steatohepatitis.Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis Host genetics predict clinical deterioration in HCV-related cirrhosis.The rs738409 (I148M) variant of the PNPLA3 gene and cirrhosis: a meta-analysis PNPLA3 I148M variant in nonalcoholic fatty liver disease: demographic and ethnic characteristics and the role of the variant in nonalcoholic fatty liver fibrosis

P2860

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P2860

PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease.

http://www.wikidata.org/entity/Q34759018

description

2010 nî lūn-bûn

@nan

2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年学术文章

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2010年学术文章

@zh-cn

2010年学术文章

@zh-hans

2010年学术文章

@zh-my

2010年学术文章

@zh-sg

2010年學術文章

@yue

name

PNPLA3 variants specifically c ...... ase but not metabolic disease.

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PNPLA3 variants specifically c ...... ase but not metabolic disease.

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PNPLA3 variants specifically c ...... ase but not metabolic disease.

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PNPLA3 variants specifically c ...... ase but not metabolic disease.

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PNPLA3 variants specifically c ...... ase but not metabolic disease.

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PNPLA3 variants specifically c ...... ase but not metabolic disease.

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PNPLA3 variants specifically c ...... ase but not metabolic disease.

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PNPLA3 variants specifically c ...... ase but not metabolic disease.

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PNPLA3 variants specifically c ...... ase but not metabolic disease.

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PNPLA3 variants specifically c ...... ase but not metabolic disease.

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Cameron D Palmer

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Elizabeth K Speliotes

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GIANT Consortium

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Joel N Hirschhorn

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Johannah L Butler

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MIGen Consortium

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P2860

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

Common variants at 30 loci contribute to polygenic dyslipidemia

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

PLINK: a tool set for whole-genome association and population-based linkage analyses

Principal components analysis corrects for stratification in genome-wide association studies

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.

A new multipoint method for genome-wide association studies by imputation of genotypes

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

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10.1002/HEP.23768

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3

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52

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Benjamin F. Voight

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2010-09-01T00:00:00Z

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45279550

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