Metabolism of GS-7340, a novel phenyl monophosphoramidate intracellular prodrug of PMPA, in blood.
about
An Odyssey in antiviral drug development-50 years at the Rega Institute: 1964-2014Role of Marine Natural Products in the Genesis of Antiviral AgentsSynthesis of nucleoside phosphate and phosphonate prodrugsProdrugs of phosphonates and phosphates: crossing the membrane barrierSelective intracellular activation of a novel prodrug of the human immunodeficiency virus reverse transcriptase inhibitor tenofovir leads to preferential distribution and accumulation in lymphatic tissue.A cutting-edge view on the current state of antiviral drug development.Natural substrate concentrations can modulate the prophylactic efficacy of nucleotide HIV reverse transcriptase inhibitors.Clinical potential of the acyclic nucleoside phosphonates cidofovir, adefovir, and tenofovir in treatment of DNA virus and retrovirus infections.Evaluation of a 7-Methoxycoumarin-3-carboxylic Acid Ester Derivative as a Fluorescent, Cell-Cleavable, Phosphonate Protecting Group.Elvitegravir, cobicistat, emtricitabine and tenofovir alafenamide for the treatment of HIV in adults.Emtricitabine + tenofovir alafenamide for the treatment of HIV.NRTI backbone in HIV treatment: will it remain relevant?Chemoprophylaxis With Oral Emtricitabine and Tenofovir Alafenamide Combination Protects Macaques From Rectal Simian/Human Immunodeficiency Virus Infection.The ProTides Boom.Rare emergence of drug resistance in HIV-1 treatment-naïve patients after 48 weeks of treatment with elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide.The Epi-TAF for Tenofovir Disoproxil Fumarate?Intracellular Activation of Tenofovir Alafenamide and the Effect of Viral and Host Protease Inhibitors.The protecting-group free selective 3'-functionalization of nucleosidesCathepsin A is the major hydrolase catalyzing the intracellular hydrolysis of the antiretroviral nucleotide phosphonoamidate prodrugs GS-7340 and GS-9131.Development of a Novel Formulation That Improves Preclinical Bioavailability of Tenofovir Disoproxil Fumarate.
P2860
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P2860
Metabolism of GS-7340, a novel phenyl monophosphoramidate intracellular prodrug of PMPA, in blood.
description
2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Metabolism of GS-7340, a novel ...... lar prodrug of PMPA, in blood.
@ast
Metabolism of GS-7340, a novel ...... lar prodrug of PMPA, in blood.
@en
Metabolism of GS-7340, a novel ...... lar prodrug of PMPA, in blood.
@nl
type
label
Metabolism of GS-7340, a novel ...... lar prodrug of PMPA, in blood.
@ast
Metabolism of GS-7340, a novel ...... lar prodrug of PMPA, in blood.
@en
Metabolism of GS-7340, a novel ...... lar prodrug of PMPA, in blood.
@nl
prefLabel
Metabolism of GS-7340, a novel ...... lar prodrug of PMPA, in blood.
@ast
Metabolism of GS-7340, a novel ...... lar prodrug of PMPA, in blood.
@en
Metabolism of GS-7340, a novel ...... lar prodrug of PMPA, in blood.
@nl
P2093
P356
P1476
Metabolism of GS-7340, a novel ...... lar prodrug of PMPA, in blood.
@en
P2093
P304
P356
10.1081/NCN-100002496
P577
2001-04-01T00:00:00Z