Phosphorylation and modulation of hyperpolarization-activated HCN4 channels by protein kinase A in the mouse sinoatrial node - Wikidata - awgldk - TriplyDB

Phosphorylation and modulation of hyperpolarization-activated HCN4 channels by protein kinase A in the mouse sinoatrial node

Phosphorylation and modulation of hyperpolarization-activated HCN4 channels by protein kinase A in the mouse sinoatrial node

http://www.wikidata.org/entity/Q34096457

about

Hyperpolarization-activated current (I(h)) in vestibular calyx terminals: characterization and role in shaping postsynaptic events.The cGMP-dependent protein kinase II Is an inhibitory modulator of the hyperpolarization-activated HCN2 channel Caveolae create local signalling domains through their distinct protein content, lipid profile and morphology Catecholamine-independent heart rate increases require Ca2+/calmodulin-dependent protein kinase II.Complete atrial-specific knockout of sodium-calcium exchange eliminates sinoatrial node pacemaker activity.Myristoylated peptides potentiate the funny current (I(f)) in sinoatrial myocytes.The mitochondrial uniporter controls fight or flight heart rate increases.Glucagon Increases Beating Rate but Not Contractility in Rat Right Atrium. Comparison with Isoproterenol Culture and adenoviral infection of sinoatrial node myocytes from adult mice Cellular context and multiple channel domains determine cAMP sensitivity of HCN4 channels: ligand-independent relief of autoinhibition in HCN4.Effects of Yiqi Tongyang on HCN4 Protein Phosphorylation in Damaged Rabbit Sinoatrial Node Cells.The Popeye Domain Containing Genes and cAMP Signaling Depressed pacemaker activity of sinoatrial node myocytes contributes to the age-dependent decline in maximum heart rate.Methods for the Isolation, Culture, and Functional Characterization of Sinoatrial Node Myocytes from Adult Mice.Consequences of dimerization of the voltage-gated proton channel.Towards an integrated view of HCN channel role in epilepsy.Anchored protein kinase A signalling in cardiac cellular electrophysiology.Cyclic AMP reverses the effects of aging on pacemaker activity and If in sinoatrial node myocytes It's not funny: How changes in If limit maximum heart rate with aging.PKA-independent activation of I(f) by cAMP in mouse sinoatrial myocytes.A mathematical model of action potentials of mouse sinoatrial node cells with molecular bases.Novel role of KT5720 on regulating hyperpolarization-activated cyclic nucleotide-gated channel activity and dorsal root ganglion neuron excitability.Phosphodiesterases 3 and 4 Differentially Regulate the Funny Current, If, in Mouse Sinoatrial Node Myocytes Investigating cyclic nucleotide and cyclic dinucleotide binding to HCN channels by surface plasmon resonance.Modeling the chronotropic effect of isoprenaline on rabbit sinoatrial node Desmosomal junctions are necessary for adult sinus node function.Electrophysiological heterogeneity of pacemaker cells in rabbit intercaval region, including SA node: insights from recording multiple ion currents in each cell.Identification of clustered phosphorylation sites in PKD2L1: how PKD2L1 channel activation is regulated by cyclic adenosine monophosphate signaling pathway.Activation of β-noradrenergic receptors enhances rhythmic bursting in mouse olfactory bulb external tufted cells.Inhibition of sarcoplasmic reticulum Ca(2+)-ATPase decreases atrioventricular node-paced heart rate in rabbits.On the Evolution of the Cardiac Pacemaker.HCN4 pacemaker channels attenuate the parasympathetic response and stabilize the spontaneous firing of the sinoatrial node.Isoprenaline: a potential contributor in sick sinus syndrome--insights from a mathematical model of the rabbit sinoatrial node.Dual Activation of Phosphodiesterases 3 and 4 Regulates Basal Spontaneous Beating Rate of Cardiac Pacemaker Cells: Role of Compartmentalization?

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P2860

Phosphorylation and modulation of hyperpolarization-activated HCN4 channels by protein kinase A in the mouse sinoatrial node

http://www.wikidata.org/entity/Q34096457

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Phosphorylation and modulation ...... A in the mouse sinoatrial node

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Phosphorylation and modulation ...... A in the mouse sinoatrial node

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Phosphorylation and modulation ...... A in the mouse sinoatrial node

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Phosphorylation and modulation ...... A in the mouse sinoatrial node

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Phosphorylation and modulation ...... A in the mouse sinoatrial node

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P1433

The Journal of General Physiology

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Phosphorylation and modulation ...... A in the mouse sinoatrial node

@en

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Catherine Proenza

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Dean Lockhead

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Eric D Larson

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Zhandi Liao

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P2860

Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channel

Molecular characterization of a slowly gating human hyperpolarization-activated channel predominantly expressed in thalamus, heart, and testis

Human disease-causing mutations disrupt an N-C-terminal interaction and channel function of bestrophin 1

Different roles for the cyclic nucleotide binding domain and amino terminus in assembly and expression of hyperpolarization-activated, cyclic nucleotide-gated channels

Properties of hyperpolarization-activated pacemaker current defined by coassembly of HCN1 and HCN2 subunits and basal modulation by cyclic nucleotide

A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker.

Distribution and prevalence of hyperpolarization-activated cation channel (HCN) mRNA expression in cardiac tissues.

Differential distribution of four hyperpolarization-activated cation channels in mouse brain.

Specific pattern of ionic channel gene expression associated with pacemaker activity in the mouse heart.

Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.

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247-258

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scholarly article

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10.1085/JGP.201010488

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3

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136

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2010-08-16T00:00:00Z

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45659861

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20713547

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P921

phosphorylation

P932

2931151

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