Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.
about
Two pacemaker channels from human heart with profoundly different activation kineticsHypoosmotic cell swelling as a novel mechanism for modulation of cloned HCN2 channels.Ivabradine -- the first selective sinus node I(f) channel inhibitor in the treatment of stable angina.Cyclic nucleotide-gated channels: an expanding new family of ion channelsMolecular characterization of a slowly gating human hyperpolarization-activated channel predominantly expressed in thalamus, heart, and testisHyperpolarization-activated current, If, in mathematical models of rabbit sinoatrial node pacemaker cellsHCN channels and heart rateFunny channel gene mutations associated with arrhythmiasNew therapeutic targets in cardiology: arrhythmias and Ca2+/calmodulin-dependent kinase II (CaMKII)Structural basis for modulation and agonist specificity of HCN pacemaker channelsA Mechanism for the Auto-inhibition of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) Channel Opening and Its Relief by cAMPAnion transport in heartSinus tachyarrhythmias and the specific bradycardic agents: a marriage made in heaven?Different roles for the cyclic nucleotide binding domain and amino terminus in assembly and expression of hyperpolarization-activated, cyclic nucleotide-gated channelsNitric oxide-cGMP pathway facilitates acetylcholine release and bradycardia during vagal nerve stimulation in the guinea-pig in vitroProperties of hyperpolarization-activated pacemaker current defined by coassembly of HCN1 and HCN2 subunits and basal modulation by cyclic nucleotideUse of an activation-specific probe to show that Rap1A and Rap1B display different sensitivities to activation by forskolin in rat1 cellsInotropy and L-type Ca2+ current, activated by beta1- and beta2-adrenoceptors, are differently controlled by phosphodiesterases 3 and 4 in rat heartHCN channels are expressed differentially in retinal bipolar cells and concentrated at synaptic terminalsLocalization of HCN1 channels to presynaptic compartments: novel plasticity that may contribute to hippocampal maturationAbsence of direct cyclic nucleotide modulation of mEAG1 and hERG1 channels revealed with fluorescence and electrophysiological methodsGenetics of sick sinus syndromeStructures of the Human HCN1 Hyperpolarization-Activated ChannelFunctional contributions of HCN channels in the primary auditory neurons of the mouse inner ear.Cocaine sensitization increases I h current channel subunit 2 (HCN₂) protein expression in structures of the mesocorticolimbic system.Hyperpolarization-activated current (I(h)) in vestibular calyx terminals: characterization and role in shaping postsynaptic events.An adenylyl cyclase signaling pathway predicts direct dopaminergic input to vestibular hair cellsProbing the order within neonatal heart rate variability.cAMP Modulation of the cytoplasmic domain in the HCN2 channel investigated by molecular simulations.Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice.Onset of atrial arrhythmias elicited by autonomic modulation of rabbit sinoatrial node activity: a modeling study.Double electron-electron resonance reveals cAMP-induced conformational change in HCN channels.Functional expression of the hyperpolarization-activated, non-selective cation current I(f) in immortalized HL-1 cardiomyocytes.The Ih Channel Gene Promotes Synaptic Transmission and Coordinated Movement in Drosophila melanogaster.A single histidine residue determines the pH sensitivity of the pacemaker channel HCN2.High I(h) channel density in the distal apical dendrite of layer V pyramidal cells increases bidirectional attenuation of EPSPs.How is the heart rate regulated in the sinoatrial node? Another piece to the puzzleGenetics and Sinus Node Dysfunction.Association between hyperpolarization-activated channel in interstitial cells of Cajal and gastrointestinal dysmotility induced by malignant ascites.Protein kinase A-independent modulation of ion channels in the brain by cyclic AMP.
P2860
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P2860
Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.
description
1991 nî lūn-bûn
@nan
1991 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.
@ast
Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.
@en
Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.
@nl
type
label
Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.
@ast
Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.
@en
Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.
@nl
prefLabel
Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.
@ast
Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.
@en
Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.
@nl
P356
P1433
P1476
Direct activation of cardiac pacemaker channels by intracellular cyclic AMP
@en
P2093
DiFrancesco D
P2888
P304
P356
10.1038/351145A0
P407
P577
1991-05-01T00:00:00Z
P6179
1038431809