Flecainide increases Kir2.1 currents by interacting with cysteine 311, decreasing the polyamine-induced rectification
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Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency.Chloroquine terminates stretch-induced atrial fibrillation more effectively than flecainide in the sheep heartDiscovery, characterization, and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.x, and Kir7.1.Cardiac and renal inward rectifier potassium channel pharmacology: emerging tools for integrative physiology and therapeutics.Biophysical and molecular characterization of a novel de novo KCNJ2 mutation associated with Andersen-Tawil syndrome and catecholaminergic polymorphic ventricular tachycardia mimicryKCNJ2 mutation causes an adrenergic-dependent rectification abnormality with calcium sensitivity and ventricular arrhythmia.STRUCTURAL AND FUNCTIONAL BASES OF CARDIAC FIBRILLATION. DIFFERENCES AND SIMILARITIES BETWEEN ATRIA AND VENTRICLES.Nav1.5 N-terminal domain binding to α1-syntrophin increases membrane density of human Kir2.1, Kir2.2 and Nav1.5 channels.Gene mutations in cardiac arrhythmias: a review of recent evidence in ion channelopathies.Tbx20 controls the expression of the KCNH2 gene and of hERG channels.Pharmacotherapy for inherited arrhythmia syndromes: mechanistic basis, clinical trial evidence and practical application.Congenital Long QT syndrome and torsade de pointes.Boosting the signal: Endothelial inward rectifier K+ channels.Nicotine at clinically relevant concentrations affects atrial inward rectifier potassium current sensitive to acetylcholine.Flecainide treats a novel KCNJ2 mutation associated with Andersen-Tawil syndrome.Zacopride selectively activates the Kir2.1 channel via a PKA signaling pathway in rat cardiomyocytes.Kir2.1-Nav1.5 Channel Complexes Are Differently Regulated than Kir2.1 and Nav1.5 Channels Alone.Druggability of the inward rectifier family: a hope for rare channelopathies?Different responses to exercise between Andersen-Tawil syndrome and catecholaminergic polymorphic ventricular tachycardia.Inward rectifying potassium currents resolved into components: modeling of complex drug actions.Skin biopsy-proven flecainide-induced neuropathy
P2860
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P2860
Flecainide increases Kir2.1 currents by interacting with cysteine 311, decreasing the polyamine-induced rectification
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
Flecainide increases Kir2.1 cu ...... olyamine-induced rectification
@ast
Flecainide increases Kir2.1 cu ...... olyamine-induced rectification
@en
Flecainide increases Kir2.1 cu ...... olyamine-induced rectification
@nl
type
label
Flecainide increases Kir2.1 cu ...... olyamine-induced rectification
@ast
Flecainide increases Kir2.1 cu ...... olyamine-induced rectification
@en
Flecainide increases Kir2.1 cu ...... olyamine-induced rectification
@nl
prefLabel
Flecainide increases Kir2.1 cu ...... olyamine-induced rectification
@ast
Flecainide increases Kir2.1 cu ...... olyamine-induced rectification
@en
Flecainide increases Kir2.1 cu ...... olyamine-induced rectification
@nl
P2093
P2860
P50
P356
P1476
Flecainide increases Kir2.1 cu ...... olyamine-induced rectification
@en
P2093
Adriana Barana
Angelica López-Izquierdo
Enrique Gálvez
Ignacio Moraleda
Irene Amorós
José Antonio Sánchez-Chapula
Juan Duarte
Lourdes Osuna
Marta González de la Fuente
Pablo Dolz-Gaitón
P2860
P304
15631-15636
P356
10.1073/PNAS.1004021107
P407
P577
2010-08-16T00:00:00Z