Phosphoinositide-mediated gating of inwardly rectifying K(+) channels.
about
Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2Neural KCNQ (Kv7) channelsHow highly charged anionic lipids bind and regulate ion channelsA Structural Determinant for the Control of PIP2 Sensitivity in G Protein-gated Inward Rectifier K+ ChannelsIdentification of yeast proteins necessary for cell-surface function of a potassium channel.Phosphoinositides: lipid regulators of membrane proteinsA dual polybasic motif determines phosphoinositide binding and regulation in the P2X channel familyCholesterol binding to ion channelsLipids driving protein structure? Evolutionary adaptations in Kir channelsRegulation of ion channel function by the host lipid bilayer examined by a stopped-flow spectrofluorometric assay.A novel mitochondrial K(ATP) channel assay.State-dependent network connectivity determines gating in a K+ channelPhosphatidylinositol 4,5-bisphosphate activates Slo3 currents and its hydrolysis underlies the epidermal growth factor-induced current inhibitionFlecainide increases Kir2.1 currents by interacting with cysteine 311, decreasing the polyamine-induced rectificationSpecific residues of the cytoplasmic domains of cardiac inward rectifier potassium channels are effective antifibrillatory targets.Gating of transient receptor potential melastatin 8 (TRPM8) channels activated by cold and chemical agonists in planar lipid bilayers.Gating of a G protein-sensitive mammalian Kir3.1 prokaryotic Kir channel chimera in planar lipid bilayersStructural dynamics of potassium-channel gating revealed by single-molecule FRET.Interplay Between Lipid Modulators of Kir2 Channels: Cholesterol and PIP2.Structural bases for the different anti-fibrillatory effects of chloroquine and quinidine.N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP2Snowflake vitreoretinal degeneration (SVD) mutation R162W provides new insights into Kir7.1 ion channel structure and functionGenetic defects in the hotspot of inwardly rectifying K(+) (Kir) channels and their metabolic consequences: a reviewIdentification of the Conformational transition pathway in PIP2 Opening Kir Channels.Phosphatidylinositol-4,5-bisphosphate regulates epidermal growth factor receptor activationPhosphoinositide control of membrane protein function: a frontier led by studies on ion channels.Mutations in Nature Conferred a High Affinity Phosphatidylinositol 4,5-Bisphosphate-binding Site in Vertebrate Inwardly Rectifying Potassium ChannelsThe molecular mechanism by which PIP(2) opens the intracellular G-loop gate of a Kir3.1 channel.Metabolic and thermal stimuli control K(2P)2.1 (TREK-1) through modular sensory and gating domains.A Quantitative Model of the GIRK1/2 Channel Reveals That Its Basal and Evoked Activities Are Controlled by Unequal Stoichiometry of Gα and Gβγ.Inhibition of inwardly rectifying Kir2.x channels by the novel anti-cancer agent gambogic acid depends on both pore block and PIP2 interference.Distant cytosolic residues mediate a two-way molecular switch that controls the modulation of inwardly rectifying potassium (Kir) channels by cholesterol and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)).The cytosolic GH loop regulates the phosphatidylinositol 4,5-bisphosphate-induced gating kinetics of Kir2 channels.Regulation of Ca(V)2 calcium channels by G protein coupled receptors.Diverse Kir modulators act in close proximity to residues implicated in phosphoinositide binding.A carboxy-terminal inter-helix linker as the site of phosphatidylinositol 4,5-bisphosphate action on Kv7 (M-type) K+ channels.Plasticity of postsynaptic, but not presynaptic, GABAB receptors in SSADH deficient mice.Kv7.1 (KCNQ1) properties and channelopathies.Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications.The Molecular Mechanism of Opening the Helix Bundle Crossing (HBC) Gate of a Kir Channel.
P2860
Q24336573-C9F0A140-9F43-41C6-AC2A-143824ABB37DQ24644947-B96FFC32-3D12-4161-AFA3-F60F399804F9Q24656180-E2932375-4593-41C6-BA06-03371A8B5D31Q27664764-7CCA01DA-8F9C-4FB0-9024-BF64F1ACD839Q27937124-832752E5-6DF8-494B-B668-95CFD2FEE3EAQ28284089-17852FBD-3182-4395-A99F-DB6DFDADA3F3Q28481252-0C671E1F-49E4-4AFF-9C98-174902441FBFQ29036398-B8525404-78AB-48F9-BD0E-F973C688CF80Q30397291-5305B810-09F5-4B15-8C19-FD62F37BA0D8Q33634122-6575D48F-38BC-41EE-9F2A-A6BB23FFF2BFQ33801956-3ABD2140-B0A5-4004-818B-99D266DB2FCEQ33865617-4013C124-A493-4C4B-BB6D-7E0225593DABQ33911315-A47AB2A3-BBF1-44DB-BD4C-05072F037D7BQ34100266-1B1DF408-2270-4C7B-91B2-2EF9E1696011Q34281602-B589DF0A-2C09-4FB4-A98A-55AD6C2128AEQ34337684-E1C7299A-4718-4D19-B994-F612916008E2Q34400860-7796DBC1-6350-44FC-B3B4-D322239F803FQ34504253-73F3F269-892C-4FCA-9815-981610D30808Q34514622-90654AC1-1F35-4953-8F9D-F42642F258DBQ34575313-C22ADB2F-D170-44D6-A7E3-D7520E21C263Q34618893-3EA8B4DF-0125-40CE-8E0B-DCFD3495287DQ34972098-DBAD9DAA-7B9A-47B3-8B0B-DF5115B97EB2Q35661470-4B344F63-5F98-4EC6-A8C3-C3F13B8640D2Q35716412-BAD7C3C1-77D7-42FD-A6A4-9A9019C20AD9Q35762279-D4FEEFF9-B5A5-4ECD-980F-0E6BB7E67BCCQ35799988-2E8BCEF0-CDD5-4122-95A8-1FAADA8F90C5Q35860472-0FC2984F-9104-4B36-B951-F92FC4874E21Q35926194-3DF73763-802E-4F9A-8B65-258FA1BB23C5Q36137577-5000617B-6049-4D65-9D9E-C9DD382A6379Q36257591-8CD1AAC8-D6A9-4B5E-8DCF-4BB3C7A071D8Q36331012-E5653DDE-4713-4B54-BF0F-6516EC994407Q36418792-F814F2FE-4416-4724-9E92-C61FA0A4E608Q36452026-4455853F-5EBD-4D19-AE5B-574D672B2C6FQ36565441-3988ED52-A05F-4729-8159-1A51B9CC6D41Q36818139-1161E64B-B4B8-4E69-9DF5-5CA91B6EF8D3Q36843204-B846B8FD-B596-4C5B-A8DB-546C3AD7DCA9Q36845652-2BE03E4B-2D48-4A12-931F-D7D72A98C062Q37049827-C0EA560D-86DF-4084-9428-0F3C0774BD99Q37073174-173773F9-488F-43BD-B92F-DBF7A29319B2Q37112835-F9F44B23-116D-42AD-B269-24E12F5A339E
P2860
Phosphoinositide-mediated gating of inwardly rectifying K(+) channels.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Phosphoinositide-mediated gating of inwardly rectifying K(+) channels.
@en
type
label
Phosphoinositide-mediated gating of inwardly rectifying K(+) channels.
@en
prefLabel
Phosphoinositide-mediated gating of inwardly rectifying K(+) channels.
@en
P2093
P2860
P1433
P1476
Phosphoinositide-mediated gating of inwardly rectifying K(+) channels.
@en
P2093
Avia Rosenhouse-Dantsker
Diomedes E Logothetis
Dmitry Lupyan
Taihao Jin
P2860
P2888
P356
10.1007/S00424-007-0276-5
P577
2007-05-23T00:00:00Z