Detection of "oncometabolite" 2-hydroxyglutarate by magnetic resonance analysis as a biomarker of IDH1/2 mutations in glioma - Wikidata - awgldk - TriplyDB

Detection of "oncometabolite" 2-hydroxyglutarate by magnetic resonance analysis as a biomarker of IDH1/2 mutations in glioma

Detection of "oncometabolite" 2-hydroxyglutarate by magnetic resonance analysis as a biomarker of IDH1/2 mutations in glioma

http://www.wikidata.org/entity/Q34101190

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Molecular Imaging of Metabolic Reprograming in Mutant IDH Cells Malignant gliomas: current perspectives in diagnosis, treatment, and early response assessment using advanced quantitative imaging methods Oligodendroglioma: pathology, molecular mechanisms and markers Metabolomics and systems pharmacology: why and how to model the human metabolic network for drug discovery Improved localisation for 2-hydroxyglutarate detection at 3T using long-TE semi-LASER Neuro-oncology: Five new things.Detection of oncogenic IDH1 mutations using magnetic resonance spectroscopy of 2-hydroxyglutarate.Genetics and imaging of oligodendroglial tumors.Magnetic Resonance (MR) Metabolic Imaging in Glioma.MR Molecular Imaging of Brain Cancer Metabolism Using Hyperpolarized 13C Magnetic Resonance Spectroscopy.Emerging treatment strategies for glioblastoma multiforme Cancer cell growth and survival as a system-level property sustained by enhanced glycolysis and mitochondrial metabolic remodeling Metabolomic signature of brain cancer.Treatment Response Assessment in IDH-Mutant Glioma Patients by Noninvasive 3D Functional Spectroscopic Mapping of 2-Hydroxyglutarate.Prognostic significance of 2-hydroxyglutarate levels in acute myeloid leukemia in China.Non-invasive detection of 2-hydroxyglutarate in IDH-mutated gliomas using two-dimensional localized correlation spectroscopy (2D L-COSY) at 7 Tesla.Non-invasive in vivo assessment of IDH1 mutational status in glioma.Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas.IDH1 and IDH2 mutations in tumorigenesis: mechanistic insights and clinical perspectives Metabolic alteration in tumorigenesis.Tumor metabolism of malignant gliomas.Canine brain tumours: a model for the human disease?The role of neuropathology in the management of patients with diffuse low grade glioma: A systematic review and evidence-based clinical practice guideline.Emerging Approaches for Targeting Metabolic Vulnerabilities in Malignant Glioma.A holistic view of cancer bioenergetics: mitochondrial function and respiration play fundamental roles in the development and progression of diverse tumors.Effective immuno-targeting of the IDH1 mutation R132H in a murine model of intracranial glioma.Hyperpolarized [1-13C] glutamate: a metabolic imaging biomarker of IDH1 mutational status in glioma Neomorphic mutations create therapeutic challenges in cancer.2-hydroxyglutarate as a magnetic resonance biomarker for glioma subtyping.Biomarkers classification and therapeutic decision-making for malignant gliomas.Conditions for (13)C NMR detection of 2-hydroxyglutarate in tissue extracts from isocitrate dehydrogenase-mutated gliomas.Selective Detection of the D-enantiomer of 2-Hydroxyglutarate in the CSF of Glioma Patients with Mutated Isocitrate Dehydrogenase.Volumetric relationship between 2-hydroxyglutarate and FLAIR hyperintensity has potential implications for radiotherapy planning of mutant IDH glioma patients.A population-based study of low-grade gliomas and mutated isocitrate dehydrogenase 1 (IDH1).MR spectroscopy for in vivo assessment of the oncometabolite 2-hydroxyglutarate and its effects on cellular metabolism in human brain gliomas at 9.4T.Imaging Markers of Isocitrate Dehydrogenase-1 Mutations in Gliomas.Pharmacodynamics of mutant-IDH1 inhibitors in glioma patients probed by in vivo 3D MRS imaging of 2-hydroxyglutarate.Non-invasive tumor genotyping using radiogenomic biomarkers, a systematic review and oncology-wide pathway analysis.900MHz 1H-/13C-NMR analysis of 2-hydroxyglutarate and other brain metabolites in human brain tumor tissue extracts

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Detection of "oncometabolite" 2-hydroxyglutarate by magnetic resonance analysis as a biomarker of IDH1/2 mutations in glioma

http://www.wikidata.org/entity/Q34101190

description

2012 nî lūn-bûn

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2012 թուականի Մարտին հրատարակուած գիտական յօդուած

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2012 թվականի մարտին հրատարակված գիտական հոդված

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2012年の論文

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Detection of "oncometabolite" ...... of IDH1/2 mutations in glioma

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Detection of "oncometabolite" ...... of IDH1/2 mutations in glioma

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Detection of "oncometabolite" ...... of IDH1/2 mutations in glioma

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Detection of "oncometabolite" ...... of IDH1/2 mutations in glioma

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Detection of "oncometabolite" ...... of IDH1/2 mutations in glioma

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Detection of "oncometabolite" ...... of IDH1/2 mutations in glioma

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Detection of "oncometabolite" ...... of IDH1/2 mutations in glioma

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Detection of "oncometabolite" ...... of IDH1/2 mutations in glioma

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Detection of "oncometabolite" ...... of IDH1/2 mutations in glioma

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Journal of Molecular Medicine

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Detection of "oncometabolite" ...... of IDH1/2 mutations in glioma

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Anne Carroll

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Danny E Mancheno

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Frank Liu

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Hui Mao

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Juliya Kalinina

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Jun Ahn

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Liya Wang

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Miao He

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Qiqi Yu

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Shaoxiong Wu

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P2860

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme

Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

Recurring mutations found by sequencing an acute myeloid leukemia genome

An integrated genomic analysis of human glioblastoma multiforme

IDH1 and IDH2 mutations in gliomas

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

The 2007 WHO classification of tumours of the central nervous system

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha

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Erwin G Van Meir

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221715068

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