Francisella tularensis antioxidants harness reactive oxygen species to restrict macrophage signaling and cytokine production - Wikidata - awgldk - TriplyDB

Francisella tularensis antioxidants harness reactive oxygen species to restrict macrophage signaling and cytokine production

Francisella tularensis antioxidants harness reactive oxygen species to restrict macrophage signaling and cytokine production

http://www.wikidata.org/entity/Q34107159

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Subversion of host recognition and defense systems by Francisella spp Involvement of a 1-Cys peroxiredoxin in bacterial virulence A 14.7 kDa protein from Francisella tularensis subsp. novicida (named FTN_1133), involved in the response to oxidative stress induced by organic peroxides, is not endowed with thiol-dependent peroxidase activity Host-adaptation of Francisella tularensis alters the bacterium's surface-carbohydrates to hinder effectors of innate and adaptive immunity.EmrA1 membrane fusion protein of Francisella tularensis LVS is required for resistance to oxidative stress, intramacrophage survival and virulence in mice.Identification of disulfide bond isomerase substrates reveals bacterial virulence factors.Discordant results obtained with Francisella tularensis during in vitro and in vivo immunological studies are attributable to compromised bacterial structural integrity.Identification of a live attenuated vaccine candidate for tularemia prophylaxis Francisella tularensis subsp. tularensis induces a unique pulmonary inflammatory response: role of bacterial gene expression in temporal regulation of host defense responses The subversion of the immune system by francisella tularensis.Hfq plays important roles in virulence and stress adaptation in Cronobacter sakazakii ATCC 29544.Preclinical testing of a vaccine candidate against tularemia.Bacterial transition metal P(1B)-ATPases: transport mechanism and roles in virulence.Prior infection with Type A Francisella tularensis antagonizes the pulmonary transcriptional response to an aerosolized Toll-like receptor 4 agonist.Development of tolerogenic dendritic cells and regulatory T cells favors exponential bacterial growth and survival during early respiratory tularemia.Identification of a novel Francisella tularensis factor required for intramacrophage survival and subversion of innate immune response.Francisella tularensis Catalase Restricts Immune Function by Impairing TRPM2 Channel Activity.Antioxidant Defenses of Francisella tularensis Modulate Macrophage Function and Production of Proinflammatory Cytokines.Francisella tularensis SchuS4 and SchuS4 lipids inhibit IL-12p40 in primary human dendritic cells by inhibition of IRF1 and IRF8.Francisella tularensis - Immune Cell Activator, Suppressor, or Stealthy Evader: The Evolving View from the Petri Dish.Glutamate utilization couples oxidative stress defense and the tricarboxylic acid cycle in Francisella phagosomal escape.Lack of OxyR and KatG Results in Extreme Susceptibility of Francisella tularensis LVS to Oxidative Stress and Marked Attenuation In vivo.Micropatterning of 3D Microenvironments for Living Biosensor Applications.Immunity to Francisella.Proteins involved in Francisella tularensis survival and replication inside macrophages.Monocyte/macrophage inflammatory response pathways to combat Francisella infection: possible therapeutic targets?Virulent Type A Francisella tularensis actively suppresses cytokine responses in human monocytes Control of intracellular Francisella tularensis by different cell types and the role of nitric oxide.Elucidation of a mechanism of oxidative stress regulation in Francisella tularensis live vaccine strain.FcγR-driven release of IL-6 by macrophages requires NOX2-dependent production of reactive oxygen species.FcγR mediates TLR2- and Syk-dependent NLRP3 inflammasome activation by inactivated Francisella tularensis LVS immune complexes.The Ability to Acquire Iron Is Inversely Related to Virulence and the Protective Efficacy of Francisella tularensis Live Vaccine Strain.Francisella Subverts Innate Immune Signaling: Focus On PI3K/Akt.

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Francisella tularensis antioxidants harness reactive oxygen species to restrict macrophage signaling and cytokine production

http://www.wikidata.org/entity/Q34107159

description

2010 nî lūn-bûn

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Francisella tularensis antioxi ...... naling and cytokine production

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Francisella tularensis antioxi ...... naling and cytokine production

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Francisella tularensis antioxi ...... naling and cytokine production

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Francisella tularensis antioxi ...... naling and cytokine production

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Francisella tularensis antioxi ...... naling and cytokine production

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Francisella tularensis antioxi ...... naling and cytokine production

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Francisella tularensis antioxi ...... naling and cytokine production

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Francisella tularensis antioxi ...... naling and cytokine production

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Francisella tularensis antioxi ...... naling and cytokine production

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JBC.M110.144394

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Journal of Biological Chemistry

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Francisella tularensis antioxi ...... naling and cytokine production

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Amanda A Melillo

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Chandra Shekhar Bakshi

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J Andrés Melendez

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P2860

MiR-155 induction by F. novicida but not the virulent F. tularensis results in SHIP down-regulation and enhanced pro-inflammatory cytokine response

Pyrin-only protein 2 modulates NF-kappaB and disrupts ASC:CLR interactions

Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity

Microarray analysis of human monocytes infected with Francisella tularensis identifies new targets of host response subversion

Reversible inactivation of the tumor suppressor PTEN by H2O2

Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo

Adaptation of Francisella tularensis to the mammalian environment is governed by cues which can be mimicked in vitro.

Rapid dissemination of Francisella tularensis and the effect of route of infection.

Macrophage pro-inflammatory response to Francisella novicida infection is regulated by SHIP.

The NF-kappa B activation pathway: a paradigm in information transfer from membrane to nucleus.

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10.1074/JBC.M110.144394

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36

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285

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