Mammalian target of rapamycin (mTOR) activation increases axonal growth capacity of injured peripheral nerves
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Extrinsic and Intrinsic Regulation of Axon Regeneration by MicroRNAs after Spinal Cord InjuryGrowth control mechanisms in neuronal regenerationAtorvastatin enhances neurite outgrowth in cortical neurons in vitro via up-regulating the Akt/mTOR and Akt/GSK-3β signaling pathwaysAdenosine Monophosphate-activated Protein Kinase (AMPK) Activators For the Prevention, Treatment and Potential Reversal of Pathological Pain.Facilitation of axon regeneration by enhancing mitochondrial transport and rescuing energy deficitsRapamycin extends life and health in C57BL/6 miceSyntaxin13 expression is regulated by mammalian target of rapamycin (mTOR) in injured neurons to promote axon regenerationMammalian target of rapamycin's distinct roles and effectiveness in promoting compensatory axonal sprouting in the injured CNS.Chemical interrogation of the neuronal kinome using a primary cell-based screening assay.An in vitro assay to study induction of the regenerative state in sensory neurons.Characterization of in vitro transcriptional responses of dorsal root ganglia cultured in the presence and absence of blastema cells from regenerating salamander limbs.Mammalian target of rapamycin: hitting the bull's-eye for neurological disorders.Generation and characterization of an Advillin-Cre driver mouse line.The necessary role of mTORC1 in central nervous system axon regeneration.Cytoskeletal disruption activates the DLK/JNK pathway, which promotes axonal regeneration and mimics a preconditioning injury.Visualizing peripheral nerve regeneration by whole mount staining.Exercise modulates microRNAs that affect the PTEN/mTOR pathway in rats after spinal cord injuryDeconvoluting mTOR biologyExpressing Constitutively Active Rheb in Adult Neurons after a Complete Spinal Cord Injury Enhances Axonal Regeneration beyond a Chondroitinase-Treated Glial Scar.Activating the translational repressor 4E-BP or reducing S6K-GSK3β activity prevents accelerated axon growth induced by hyperactive mTOR in vivo.HDAC5 is a novel injury-regulated tubulin deacetylase controlling axon regenerationTissue-type plasminogen activator regulates the neuronal uptake of glucose in the ischemic brain.mTORC1 is necessary but mTORC2 and GSK3β are inhibitory for AKT3-induced axon regeneration in the central nervous system.Expressing Constitutively Active Rheb in Adult Dorsal Root Ganglion Neurons Enhances the Integration of Sensory Axons that Regenerate Across a Chondroitinase-Treated Dorsal Root Entry Zone Following Dorsal Root Crush.PI3K-GSK3 signalling regulates mammalian axon regeneration by inducing the expression of Smad1.Rapamycin-Resistant mTOR Activity Is Required for Sensory Axon Regeneration Induced by a Conditioning Lesion.Epigenetic Regulation of Axon Regeneration after Neural Injury.Injury-induced HDAC5 nuclear export is essential for axon regeneration.Subcellular communication through RNA transport and localized protein synthesismTOR kinase, a key player in the regulation of glial functions: relevance for the therapy of multiple sclerosis.Axonal regeneration after spinal cord injury in zebrafish and mammals: differences, similarities, translation.Cell intrinsic control of axon regeneration.Signaling regulations of neuronal regenerative ability.Identifying the role of microRNAs in spinal cord injury.mTOR in Brain Physiology and Pathologies.Targeting molecules to medicine with mTOR, autophagy and neurodegenerative disorders.Stress Increases Peripheral Axon Growth and Regeneration through Glucocorticoid Receptor-Dependent Transcriptional Programs.Models of axon regeneration in Drosophila.Targeting AMPK for the Alleviation of Pathological Pain.Proteomic and functional annotation analysis of injured peripheral nerves reveals ApoE as a protein upregulated by injury that is modulated by metformin treatment.
P2860
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P2860
Mammalian target of rapamycin (mTOR) activation increases axonal growth capacity of injured peripheral nerves
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Mammalian target of rapamycin ...... y of injured peripheral nerves
@ast
Mammalian target of rapamycin ...... y of injured peripheral nerves
@en
type
label
Mammalian target of rapamycin ...... y of injured peripheral nerves
@ast
Mammalian target of rapamycin ...... y of injured peripheral nerves
@en
prefLabel
Mammalian target of rapamycin ...... y of injured peripheral nerves
@ast
Mammalian target of rapamycin ...... y of injured peripheral nerves
@en
P2093
P2860
P356
P1476
Mammalian target of rapamycin ...... y of injured peripheral nerves
@en
P2093
Michael J Gambello
Namiko Abe
Steven H Borson
Valeria Cavalli
P2860
P304
28034-28043
P356
10.1074/JBC.M110.125336
P407
P577
2010-07-08T00:00:00Z