Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma. - Wikidata - awgldk - TriplyDB

Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma.

Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma.

http://www.wikidata.org/entity/Q34109415

about

Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting Children's Oncology Group's 2013 blueprint for research: bone tumors Clinical and biochemical function of polymorphic NR0B1 GGAA-microsatellites in Ewing sarcoma: a report from the Children's Oncology Group Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma.BCL11B is up-regulated by EWS/FLI and contributes to the transformed phenotype in Ewing sarcoma Promiscuous partnerships in Ewing's sarcoma.EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma.Glutathione s-transferases in pediatric cancer.Recent advances in the molecular pathogenesis of Ewing's sarcoma.Children's Oncology Group's 2013 blueprint for research: epidemiology Genomic and biochemical insights into the specificity of ETS transcription factors.Blocking the road, stopping the engine or killing the driver? Advances in targeting EWS/FLI-1 fusion in Ewing sarcoma as novel therapy.Role for the EWS domain of EWS/FLI in binding GGAA-microsatellites required for Ewing sarcoma anchorage independent growth.Tumor-specific retargeting of an oncogenic transcription factor chimera results in dysregulation of chromatin and transcription.EWS/FLI utilizes NKX2-2 to repress mesenchymal features of Ewing sarcoma.A polypeptide from the junction region sequence of EWS-FLI1 inhibits Ewing's sarcoma cells, interacts with the EWS-FLI1 and partner proteins.Microsatellites with macro-influence in ewing sarcoma Salient features of mesenchymal stem cells-implications for Ewing sarcoma modeling.The possible functions of duplicated ets (GGAA) motifs located near transcription start sites of various human genes Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus.Identification of two types of GGAA-microsatellites and their roles in EWS/FLI binding and gene regulation in Ewing sarcoma.Using targeted virotherapy to treat a resistant Ewing sarcoma model: from the bedside to the bench and back.

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P2860

Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma.

http://www.wikidata.org/entity/Q34109415

description

2010 nî lūn-bûn

@nan

2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma.

@ast

Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma.

@en

Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma.

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type

label

Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma.

@ast

Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma.

@en

Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma.

@nl

prefLabel

Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma.

@ast

Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma.

@en

Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma.

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P1476

Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma.

@en

P2093

Camille A Enriquez

http://www.w3.org/2001/XMLSchema#string

Christopher P Hill

http://www.w3.org/2001/XMLSchema#string

Devin Close

http://www.w3.org/2001/XMLSchema#string

Kunal Gangwal

http://www.w3.org/2001/XMLSchema#string

Stephen L Lessnick

http://www.w3.org/2001/XMLSchema#string

P2860

Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1

A new member of the ETS family fused to EWS in Ewing tumors

The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1

Structural studies of Ets-1/Pax5 complex formation on DNA

Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization

Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma

TLS, EWS and TAF15: a model for transcriptional integration of gene expression

A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG

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177-187

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scholarly article

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10.1177/1947601910361495

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2

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1

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20827386

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