N-alkyl urea hydroxamic acids as a new class of peptide deformylase inhibitors with antibacterial activity
about
Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibioticsTrapping conformational states along ligand-binding dynamics of peptide deformylase: the impact of induced fit on enzyme catalysisFmt bypass in Pseudomonas aeruginosa causes induction of MexXY efflux pump expressionPeptide deformylase inhibitors as antibacterial agents: identification of VRC3375, a proline-3-alkylsuccinyl hydroxamate derivative, by using an integrated combinatorial and medicinal chemistry approach.Comparative antimicrobial characterization of LBM415 (NVP PDF-713), a new peptide deformylase inhibitor of clinical importance.Challenges of antibacterial discoveryPeptide deformylase inhibitors as potent antimycobacterial agents.Antibiotic resistance in Staphylococcus aureus: concerns, causes and cures.Parasite plastids: approaching the endgame.Antimalarial drugs: current status and new developments.Therapeutic potential of peptide deformylase inhibitors.Drug forecast - the peptide deformylase inhibitors as antibacterial agents.Mutations in three distinct loci cause resistance to peptide deformylase inhibitors in Bacillus subtilis.A unique peptide deformylase platform to rationally design and challenge novel active compounds.Peptide deformylase--a promising therapeutic target for tuberculosis and antibacterial drug discovery.Pharmacokinetics in animals and humans of a first-in-class peptide deformylase inhibitor.MRSA: the first half century.Subinhibitory concentrations of the deformylase inhibitor actinonin increase bacterial release of neutrophil-activating peptides: a new approach to antimicrobial chemotherapy.Novel targets for antibiotics in Staphylococcus aureus.The Search for Herbal Antibiotics: An In-Silico Investigation of Antibacterial Phytochemicals.An improved crystal form of Plasmodium falciparum peptide deformylaseURD12: A urea derivative with marked antitumor activities.Virtual Screening Approach of Bacterial Peptide Deformylase Inhibitors Results in New Antibiotics.Ureidopyrazine Derivatives: Synthesis and Biological Evaluation as Anti-Infectives and Abiotic Elicitors.Reconstitution of Mammalian Enzymatic Deacylation Reactions in Live Bacteria Using Native Acylated Substrates
P2860
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P2860
N-alkyl urea hydroxamic acids as a new class of peptide deformylase inhibitors with antibacterial activity
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
N-alkyl urea hydroxamic acids ...... rs with antibacterial activity
@ast
N-alkyl urea hydroxamic acids ...... rs with antibacterial activity
@en
N-alkyl urea hydroxamic acids ...... rs with antibacterial activity
@nl
type
label
N-alkyl urea hydroxamic acids ...... rs with antibacterial activity
@ast
N-alkyl urea hydroxamic acids ...... rs with antibacterial activity
@en
N-alkyl urea hydroxamic acids ...... rs with antibacterial activity
@nl
prefLabel
N-alkyl urea hydroxamic acids ...... rs with antibacterial activity
@ast
N-alkyl urea hydroxamic acids ...... rs with antibacterial activity
@en
N-alkyl urea hydroxamic acids ...... rs with antibacterial activity
@nl
P2093
P2860
P1476
N-alkyl urea hydroxamic acids ...... rs with antibacterial activity
@en
P2093
Beat Weidmann
Charlotte Wu
Corinne J Hackbarth
Dawn Z Chen
Dinesh V Patel
Elina Dunn
George Withers
James B Mangold
Jason G Lewis
P2860
P304
P356
10.1128/AAC.46.9.2752-2764.2002
P407
P577
2002-09-01T00:00:00Z