Peptide deformylase--a promising therapeutic target for tuberculosis and antibacterial drug discovery. - Wikidata - awgldk - TriplyDB

Peptide deformylase--a promising therapeutic target for tuberculosis and antibacterial drug discovery.

Peptide deformylase--a promising therapeutic target for tuberculosis and antibacterial drug discovery.

http://www.wikidata.org/entity/Q37521070

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Hydroxamic acids as potent inhibitors of Fe(II) and Mn(II) E. coli methionine aminopeptidase: biological activities and X-ray structures of oxazole hydroxamate-EcMetAP-Mn complexes Challenges of antibacterial discovery High tolerance to mutations in a Chlamydia trachomatis peptide deformylase loop Inhibition of human mitochondrial peptide deformylase causes apoptosis in c-myc-overexpressing hematopoietic cancers.Recent derivatives from smaller classes of fermentation-derived antibacterials.Lack of formylated methionyl-tRNA has pleiotropic effects on Bacillus subtilis.Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion.

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Peptide deformylase--a promising therapeutic target for tuberculosis and antibacterial drug discovery.

http://www.wikidata.org/entity/Q37521070

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on July 2009

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

Peptide deformylase--a promisi ...... antibacterial drug discovery.

@en

Peptide deformylase--a promisi ...... antibacterial drug discovery.

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type

label

Peptide deformylase--a promisi ...... antibacterial drug discovery.

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Peptide deformylase--a promisi ...... antibacterial drug discovery.

@nl

prefLabel

Peptide deformylase--a promisi ...... antibacterial drug discovery.

@en

Peptide deformylase--a promisi ...... antibacterial drug discovery.

@nl

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Expert Opinion on Therapeutic Targets

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Peptide deformylase--a promisi ...... antibacterial drug discovery.

@en

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Anshika Sharma

http://www.w3.org/2001/XMLSchema#string

Gopal K Khuller

http://www.w3.org/2001/XMLSchema#string

Sadhna Sharma

http://www.w3.org/2001/XMLSchema#string

P2860

An unusual peptide deformylase features in the human mitochondrial N-terminal methionine excision pathway

Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms

N-formylmethionyl-sRNA as the initiator of protein synthesis

Methionine aminopeptidase gene of Escherichia coli is essential for cell growth

Antibiotic Activity and Characterization of BB-3497, a Novel Peptide Deformylase Inhibitor

The crystal structures of four peptide deformylases bound to the antibiotic actinonin reveal two distinct types: a platform for the structure-based design of antibacterial agents

Structure analysis of peptide deformylases from Streptococcus pneumoniae, Staphylococcus aureus, Thermotoga maritima and Pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase

Synthesis and characterization of cytidine derivatives that inhibit the kinase IspE of the non-mevalonate pathway for isoprenoid biosynthesis

Characterization of peptide deformylase2 from B. cereus

A peptide deformylase-ribosome complex reveals mechanism of nascent chain processing

P304

753-765

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scholarly article

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10.1517/14728220903005590

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7

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13

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2009-07-01T00:00:00Z

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19530983

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P921

Akafuba bulwadde