Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma - Wikidata - awgldk - TriplyDB

Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma

Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma

http://www.wikidata.org/entity/Q34116250

about

Mitochondrial disulfide relay mediates translocation of p53 and partitions its subcellular activity Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck Increased Oxidative Stress as a Selective Anticancer Therapy Redox regulation of mitochondrial biogenesis Reactive oxygen species in cancer stem cells Mitochondrial DNA alterations and mitochondrial dysfunction in the progression of hepatocellular carcinoma Role of the p53 tumor suppressor in metabolism Tumor suppressor p53 and its mutants in cancer metabolism The role of tumor suppressor p53 in the antioxidant defense and metabolism Reperfusion promotes mitochondrial biogenesis following focal cerebral ischemia in rats Differential Protein Distribution between the Nucleus and Mitochondria: Implications in Aging Nrf2 protects mitochondrial decay by oxidative stress p53 Regulates oxidative stress-mediated retrograde signaling: a novel mechanism for chemotherapy-induced cardiac injury Cisplatin induces a mitochondrial-ROS response that contributes to cytotoxicity depending on mitochondrial redox status and bioenergetic functions Manganese superoxide dismutase is a mitochondrial fidelity protein that protects Polγ against UV-induced inactivation Role of mitochondrial dysfunction in cancer progression LACE1 interacts with p53 and mediates its mitochondrial translocation and apoptosis Clinical significance in oral cavity squamous cell carcinoma of pathogenic somatic mitochondrial mutations.Increased distributional variance of mitochondrial DNA content associated with prostate cancer cells as compared with normal prostate cells Methylation profile of TP53 regulatory pathway and mtDNA alterations in breast cancer patients lacking TP53 mutations.Mitochondrial matrix P53 sensitizes cells to oxidative stress.Tumor suppressor p53 and estrogen receptors in nuclear-mitochondrial communication.Mutant p53 exhibits trivial effects on mitochondrial functions which can be reactivated by ellipticine in lymphoma cells.p53 and mitochondrial function in neurons.Physical exercise regulates p53 activity targeting SCO2 and increases mitochondrial COX biogenesis in cardiac muscle with age.Mitochondrial translocation of p53 modulates neuronal fate by preventing differentiation-induced mitochondrial stress.Nuclear transcription factors in mammalian mitochondria p53: exercise capacity and metabolism.Mitochondrial DNA maintenance is regulated in human hepatoma cells by glycogen synthase kinase 3β and p53 in response to tumor necrosis factor α.Molecular bases of progeroid syndromes.Preferential killing of cancer cells with mitochondrial dysfunction by natural compounds.Reduced mitochondrial DNA content associates with poor prognosis of prostate cancer in African American men.Common 4977 bp deletion and novel alterations in mitochondrial DNA in Vietnamese patients with breast cancer Mitochondrial dysfunction impairs tumor suppressor p53 expression/function.Inhibition of store-operated calcium entry attenuates MPP(+)-induced oxidative stress via preservation of mitochondrial function in PC12 cells: involvement of Homer1a.Efficient mitochondrial biogenesis drives incomplete penetrance in Leber's hereditary optic neuropathy.p53, aerobic metabolism, and cancer.Review: mitochondrial defects in breast cancer Mitochondrial DNA content varies with pathological characteristics of breast cancer.Hyperoxia activates ATM independent from mitochondrial ROS and dysfunction.

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Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma

http://www.wikidata.org/entity/Q34116250

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2005 nî lūn-bûn

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2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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Novel role of p53 in maintaini ...... interaction with DNA Pol gamma

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Novel role of p53 in maintaini ...... interaction with DNA Pol gamma

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Novel role of p53 in maintaini ...... interaction with DNA Pol gamma

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Novel role of p53 in maintaini ...... interaction with DNA Pol gamma

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Novel role of p53 in maintaini ...... interaction with DNA Pol gamma

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Novel role of p53 in maintaini ...... interaction with DNA Pol gamma

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Novel role of p53 in maintaini ...... interaction with DNA Pol gamma

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SJ.EMBOJ.7600819

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The EMBO Journal

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Novel role of p53 in maintaini ...... interaction with DNA Pol gamma

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Geetha Achanta

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Helene Pelicano

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Jennifer S Carew

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Li Feng

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Peng Huang

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Ryohei Sasaki

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Weiqin Lu

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P2860

Premature ageing in mice expressing defective mitochondrial DNA polymerase

p53 has a direct apoptogenic role at the mitochondria

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

Reconstitution of a minimal mtDNA replisome in vitro

Mitochondrial defects in cancer

Sequence and organization of the human mitochondrial genome

Surfing the p53 network

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

Mitochondrial diseases in man and mouse

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19

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24

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Michael J. Keating

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7600320

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16163384

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1276176

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