Role of the water-metal ion bridge in mediating interactions between quinolones and Escherichia coli topoisomerase IV.
about
Catalytic core of human topoisomerase IIα: insights into enzyme-DNA interactions and drug mechanismFluoroquinolones stimulate the DNA cleavage activity of topoisomerase IV by promoting the binding of Mg(2+) to the second metal binding site.Fluoroquinolone interactions with Mycobacterium tuberculosis gyrase: Enhancing drug activity against wild-type and resistant gyrase.Crystal structure and stability of gyrase-fluoroquinolone cleaved complexes from Mycobacterium tuberculosis.Suppression of gyrase-mediated resistance by C7 aryl fluoroquinolones.Safety issues and drug-drug interactions with commonly used quinolones.Recognition of DNA Supercoil Geometry by Mycobacterium tuberculosis Gyrase.Interactions between Quinolones and Bacillus anthracis Gyrase and the Basis of Drug Resistance.Activities of gyrase and topoisomerase IV on positively supercoiled DNA.Novel xanthone-polyamine conjugates as catalytic inhibitors of human topoisomerase IIα.Design, synthesis, and evaluation of novel N-1 fluoroquinolone derivatives: Probing for binding contact with the active site tyrosine of gyrase.
P2860
Q34379629-97FE3A7B-F03B-465C-87FD-45DF09FF61B7Q36483838-10430356-F9FA-496A-986B-0B3F2121D76BQ36607348-821D7FDE-7ACF-44E2-9716-29F47F4509EBQ36607637-199C813B-4733-459C-A836-80121C2F70F2Q36817994-452C5032-786B-4AC7-90E6-3AAF654B03FBQ38271318-E5080A5F-1A69-4617-B20F-D4A1F6B0E642Q42261392-DCF83AF2-A119-4241-9B05-65C8428361AAQ46335874-E736307D-1CB4-4ACC-ACFE-CD38DB863523Q47766774-83E6EC0F-AFDA-47F2-8388-BAFCC4FE0486Q47789316-E2DF57EB-1B83-4407-835E-1CF7073F8957Q52319877-EAAB7091-796D-448A-91D0-04E9111F7D93
P2860
Role of the water-metal ion bridge in mediating interactions between quinolones and Escherichia coli topoisomerase IV.
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Role of the water-metal ion br ...... erichia coli topoisomerase IV.
@ast
Role of the water-metal ion br ...... erichia coli topoisomerase IV.
@en
Role of the water-metal ion br ...... erichia coli topoisomerase IV.
@nl
type
label
Role of the water-metal ion br ...... erichia coli topoisomerase IV.
@ast
Role of the water-metal ion br ...... erichia coli topoisomerase IV.
@en
Role of the water-metal ion br ...... erichia coli topoisomerase IV.
@nl
prefLabel
Role of the water-metal ion br ...... erichia coli topoisomerase IV.
@ast
Role of the water-metal ion br ...... erichia coli topoisomerase IV.
@en
Role of the water-metal ion br ...... erichia coli topoisomerase IV.
@nl
P2093
P2860
P356
P1433
P1476
Role of the water-metal ion br ...... herichia coli topoisomerase IV
@en
P2093
Erin J Breland
Katie J Aldred
Marie-Paule Strub
Neil Osheroff
Robert J Kerns
Vladislava Vlčková
P2860
P304
P356
10.1021/BI500682E
P407
P577
2014-08-21T00:00:00Z