Tissue-specific and age-dependent effects of global Mdm2 loss
about
MDM2 prevents spontaneous tubular epithelial cell death and acute kidney injury.Aberrant activation of p53 due to loss of MDM2 or MDMX causes early lens dysmorphogenesis.Mdm proteins: critical regulators of embry ogenesis and homeostasis.Limiting the power of p53 through the ubiquitin proteasome pathway.Distinct downstream targets manifest p53-dependent pathologies in mice.Indispensable role of Mdm2/p53 interaction during the embryonic and postnatal inner ear development.Mdm2 inhibition confers protection of p53-proficient cells from the cytotoxic effects of Wee1 inhibitorsCell cycle control in the kidney.The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression.Mouse modelling of the MDM2/MDMX-p53 signalling axis.Autophagy and p53.Negative auto-regulators trap p53 in their web.p53 Activity Dominates That of p73 upon Mdm4 Loss in Development and Tumorigenesis.Tumor-specific signaling to p53 is mimicked by Mdm2 inactivation in zebrafish: insights from mdm2 and mdm4 mutant zebrafishMdm2 Is Required for Survival and Growth of p53-Deficient Cancer Cells.The Enigma of p53.Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity.
P2860
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P2860
Tissue-specific and age-dependent effects of global Mdm2 loss
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Tissue-specific and age-dependent effects of global Mdm2 loss
@ast
Tissue-specific and age-dependent effects of global Mdm2 loss
@en
Tissue-specific and age-dependent effects of global Mdm2 loss
@nl
type
label
Tissue-specific and age-dependent effects of global Mdm2 loss
@ast
Tissue-specific and age-dependent effects of global Mdm2 loss
@en
Tissue-specific and age-dependent effects of global Mdm2 loss
@nl
prefLabel
Tissue-specific and age-dependent effects of global Mdm2 loss
@ast
Tissue-specific and age-dependent effects of global Mdm2 loss
@en
Tissue-specific and age-dependent effects of global Mdm2 loss
@nl
P2093
P2860
P356
P1476
Tissue-specific and age-dependent effects of global Mdm2 loss
@en
P2093
Carolyn Van Pelt
Guillermina Lozano
Laura Pageon
Mehrnoosh Tashakori
Mingjian James You
Shunbin Xiong
P2860
P304
P356
10.1002/PATH.4368
P577
2014-06-09T00:00:00Z