The Epstein-Barr virus-encoded G protein-coupled receptor BILF1 hetero-oligomerizes with human CXCR4, scavenges Gαi proteins, and constitutively impairs CXCR4 functioning.
about
β-Arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKRChemokine receptor oligomerization and allostery.Molecular mechanisms deployed by virally encoded G protein-coupled receptors in human diseases.Design and pharmacological characterization of VUF14480, a covalent partial agonist that interacts with cysteine 98(3.36) of the human histamine H₄ receptor.Modulation of cellular signaling by herpesvirus-encoded G protein-coupled receptors.Chemokine and chemokine receptor structure and interactions: implications for therapeutic strategies.Hunting for the function of orphan GPCRs - beyond the search for the endogenous ligand.A betabaculovirus encoding a gp64 homolog.Biological Significance of GPCR Heteromerization in the Neuro-Endocrine SystemConstitutive formation of an RXFP1-signalosome: a novel paradigm in GPCR function and regulation.EBV BILF1 evolved to downregulate cell surface display of a wide range of HLA class I molecules through their cytoplasmic tail.Disulfide Trapping for Modeling and Structure Determination of Receptor: Chemokine Complexes.The US27 gene product of human cytomegalovirus enhances signaling of host chemokine receptor CXCR4.Autocrine CCL3 and CCL4 induced by the oncoprotein LMP1 promote Epstein-Barr virus-triggered B cell proliferation.G protein-coupled receptors: walking hand-in-hand, talking hand-in-hand?Pharmacological modulation of chemokine receptor function.History and biological significance of GPCR heteromerization in the neuroendocrine system.CXCL12 signaling in the development of the nervous system.Herpesvirus-encoded GPCRs: neglected players in inflammatory and proliferative diseases?CXCR4: a virus's best friend?Viral manipulation of the host immune response.Production of Chemokine/Chemokine Receptor Complexes for Structural Biophysical Studies.What Do Structures Tell Us About Chemokine Receptor Function and Antagonism?Hijacking GPCRs by viral pathogens and tumor.EBV glycoproteins: where are we now?Manipulation of the host cell membrane by human γ-herpesviruses EBV and KSHV for pathogenesis.A general method for site specific fluorescent labeling of recombinant chemokines.Mechanisms of Regulation of the Chemokine-Receptor Network.Identification and profiling of CXCR3-CXCR4 chemokine receptor heteromer complexes.The 7-transmembrane protein homologue UL78 of the human cytomegalovirus forms oligomers and traffics between the plasma membrane and different intracellular compartments.Epstein-Barr virus deubiquitinase downregulates TRAF6-mediated NF-κB signaling during productive replication.The Viral G Protein-Coupled Receptor ORF74 Hijacks β-Arrestins for Endocytic Trafficking in Response to Human Chemokines.Attenuation of chemokine receptor function and surface expression as an immunomodulatory strategy employed by human cytomegalovirus is linked to vGPCR US28.Human Cytomegalovirus UL111A and US27 gene products enhance the CXCL12/CXCR4 signaling axis via distinct mechanisms.The Immunomodulatory Capacity of an Epstein-Barr Virus Abortive Lytic Cycle: Potential Contribution to Viral Tumorigenesis.
P2860
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P2860
The Epstein-Barr virus-encoded G protein-coupled receptor BILF1 hetero-oligomerizes with human CXCR4, scavenges Gαi proteins, and constitutively impairs CXCR4 functioning.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The Epstein-Barr virus-encoded ...... ely impairs CXCR4 functioning.
@ast
The Epstein-Barr virus-encoded ...... ely impairs CXCR4 functioning.
@en
The Epstein-Barr virus-encoded ...... ely impairs CXCR4 functioning.
@nl
type
label
The Epstein-Barr virus-encoded ...... ely impairs CXCR4 functioning.
@ast
The Epstein-Barr virus-encoded ...... ely impairs CXCR4 functioning.
@en
The Epstein-Barr virus-encoded ...... ely impairs CXCR4 functioning.
@nl
prefLabel
The Epstein-Barr virus-encoded ...... ely impairs CXCR4 functioning.
@ast
The Epstein-Barr virus-encoded ...... ely impairs CXCR4 functioning.
@en
The Epstein-Barr virus-encoded ...... ely impairs CXCR4 functioning.
@nl
P2093
P2860
P356
P1476
The Epstein-Barr virus-encoded ...... ely impairs CXCR4 functioning.
@en
P2093
Henry F Vischer
Martine J Smit
P2860
P304
29632-29641
P356
10.1074/JBC.M110.115618
P407
P577
2010-07-09T00:00:00Z