Function assignment to conserved residues in mammalian alkaline phosphatases. - Wikidata - awgldk - TriplyDB

Function assignment to conserved residues in mammalian alkaline phosphatases.

Function assignment to conserved residues in mammalian alkaline phosphatases.

http://www.wikidata.org/entity/Q34122485

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Targeting the active site of the placental isozyme of alkaline phosphatase by phage-displayed scFv antibodies selected by a specific uncompetitive inhibitor Refined structures of placental alkaline phosphatase show a consistent pattern of interactions at the peripheral site Molecular evolution of the tissue-nonspecific alkaline phosphatase allows prediction and validation of missense mutations responsible for hypophosphatasia Exonic splicing signals impose constraints upon the evolution of enzymatic activity.Assay format as a critical success factor for identification of novel inhibitor chemotypes of tissue-nonspecific alkaline phosphatase from high-throughput screening Cellular function and molecular structure of ecto-nucleotidases.Structural evidence of functional divergence in human alkaline phosphatases.Alkaline Phosphatases : Structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes Catalytic signature of a heat-stable, chimeric human alkaline phosphatase with therapeutic potential.Alkaline phosphatase in stem cells.Structural studies of human alkaline phosphatase in complex with strontium: implication for its secondary effect in bones Alkaline Phosphatase and Hypophosphatasia.Recombinant production and characterization of a highly active alkaline phosphatase from marine bacterium Cobetia marina.Cobalt and chromium exposure affects osteoblast function and impairs the mineralization of prosthesis surfaces in vitro.Phosphate binding in the active site of alkaline phosphatase and the interactions of 2-nitrosoacetophenone with alkaline phosphatase-induced small structural changes.Distinct structure and activity recoveries reveal differences in metal binding between mammalian and Escherichia coli alkaline phosphatases.Heat shock induces intestinal-type alkaline phosphatase in rat IEC-18 cells.Chronic Cadmium Exposure Lead to Inhibition of Serum and Hepatic Alkaline Phosphatase Activity in Wistar Rats.Effects of replacing active site residues in a cold-active alkaline phosphatase with those found in its mesophilic counterpart from Escherichia coli.Cloning and expression pattern of alkaline phosphatase during the development of Paralichthys olivaceus.Sequence and functional analysis of intestinal alkaline phosphatase from Lateolabrax maculatus.Simultaneous retention of thermostability and specific activity in chimeric human alkaline phosphatases.

P2860

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P2860

Function assignment to conserved residues in mammalian alkaline phosphatases.

http://www.wikidata.org/entity/Q34122485

description

2002 nî lūn-bûn

@nan

2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի ապրիլին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

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2002年论文

@wuu

name

Function assignment to conserved residues in mammalian alkaline phosphatases.

@ast

Function assignment to conserved residues in mammalian alkaline phosphatases.

@en

Function assignment to conserved residues in mammalian alkaline phosphatases.

@nl

type

label

Function assignment to conserved residues in mammalian alkaline phosphatases.

@ast

Function assignment to conserved residues in mammalian alkaline phosphatases.

@en

Function assignment to conserved residues in mammalian alkaline phosphatases.

@nl

prefLabel

Function assignment to conserved residues in mammalian alkaline phosphatases.

@ast

Function assignment to conserved residues in mammalian alkaline phosphatases.

@en

Function assignment to conserved residues in mammalian alkaline phosphatases.

@nl

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P1433

Journal of Biological Chemistry

P1476

Function assignment to conserved residues in mammalian alkaline phosphatases.

@en

P2093

Alexey Kozlenkov

http://www.w3.org/2001/XMLSchema#string

José Luis Millán

http://www.w3.org/2001/XMLSchema#string

Marc F Hoylaerts

http://www.w3.org/2001/XMLSchema#string

Thomas Manes

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P2860

Aspartic acid-484 of nascent placental alkaline phosphatase condenses with a phosphatidylinositol glycan to become the carboxyl terminus of the mature enzyme

Crystal structure of alkaline phosphatase from human placenta at 1.8 A resolution. Implication for a substrate specificity

Reaction mechanism of alkaline phosphatase based on crystal structures. Two-metal ion catalysis

Mutations at positions 153 and 328 in Escherichia coli alkaline phosphatase provide insight towards the structure and function of mammalian and yeast alkaline phosphatases

Kinetic and structural consequences of replacing the aspartate bridge by asparagine in the catalytic metal triad of Escherichia coli alkaline phosphatase

VMD: visual molecular dynamics

Site-directed mutagenesis and epitope-mapped monoclonal antibodies define a catalytically important conformational difference between human placental and germ cell alkaline phosphatase.

Molecular mechanism of uncompetitive inhibition of human placental and germ-cell alkaline phosphatase.

Nicotinamide-adenine dinucleotide inhibition of pig kidney alkaline phosphatase.

Gly429 is the major determinant of uncompetitive inhibition of human germ cell alkaline phosphatase by L-leucine.

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22992-22999

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scholarly article

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10.1074/JBC.M202298200

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25

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277

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2002-04-05T00:00:00Z

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11937510

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