Inhibition of ADAM-TS4 and ADAM-TS5 prevents aggrecan degradation in osteoarthritic cartilage.
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Negative effects of ADAMTS-7 and ADAMTS-12 on endplate cartilage differentiationProprotein convertase furin interacts with and cleaves pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi networkInhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulinADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis.The protective effect of licofelone on experimental osteoarthritis is correlated with the downregulation of gene expression and protein synthesis of several major cartilage catabolic factors: MMP-13, cathepsin K and aggrecanases.Detecting early stage osteoarthritis by optical coherence tomography?Processing and localization of ADAMTS-1 and proteolytic cleavage of versican during cumulus matrix expansion and ovulationReview of Prospects of Biological Fluid Biomarkers in Osteoarthritis.Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes.Patients with rheumatoid arthritis have an altered circulatory aggrecan profile.Investigation of the direct effects of salmon calcitonin on human osteoarthritic chondrocytesRole of ADAM and ADAMTS metalloproteinases in airway diseases.MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responsesGlobal effects of BKV infection on gene expression in human primary kidney epithelial cells.Mechanical load inhibits IL-1 induced matrix degradation in articular cartilageMicroRNA-140 plays dual roles in both cartilage development and homeostasis.ADAMTS4 and ADAMTS5 knockout mice are protected from versican but not aggrecan or brevican proteolysis during spinal cord injury.Granulin-epithelin precursor binds directly to ADAMTS-7 and ADAMTS-12 and inhibits their degradation of cartilage oligomeric matrix proteinThe roles of catabolic factors in the development of osteoarthritis.Cloning and expression of ADAM-related metalloproteases in equine laminitisADAMTS-4 and ADAMTS-5: key enzymes in osteoarthritis.ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfateCordycepin modulates inflammatory and catabolic gene expression in interleukin-1beta-induced human chondrocytes from advanced-stage osteoarthritis: an in vitro studyAdipose-derived stromal cells protect intervertebral disc cells in compression: implications for stem cell regenerative disc therapy.Metalloproteinases: their role in arthritis and potential as therapeutic targets.Roles of metalloproteinase-3 and aggrecanase 1 and 2 in aggrecan cleavage during human meniscus degeneration.Imbalanced protein expression patterns of anabolic, catabolic, anti-catabolic and inflammatory cytokines in degenerative cervical disc cells: new indications for gene therapeutic treatments of cervical disc diseasesADAMTS-18: a metalloproteinase with multiple functionsFibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes.Discovery of Potent and Selective Inhibitors for ADAMTS-4 through DNA-Encoded Library Technology (ELT).Identification and characterization of human nucleus pulposus cell specific serotypes of adeno-associated virus for gene therapeutic approaches of intervertebral disc disordersTranslational development of an ADAMTS-5 antibody for osteoarthritis disease modification.Epigenetic mechanisms underlying the aberrant catabolic and anabolic activities of osteoarthritic chondrocytes.Bovine lactoferricin is anti-inflammatory and anti-catabolic in human articular cartilage and synoviumA Disintegrin and Metalloproteinase with Thrombospondin Motifs-5 (ADAMTS-5) Forms Catalytically Active OligomersSyndecan-4 in intervertebral disc and cartilage: Saint or synner?Age-dependent increase of discoidin domain receptor 2 and matrix metalloproteinase 13 expression in temporomandibular joint cartilage of type IX and type XI collagen-deficient mice.A combinatorial relative mass value evaluation of endogenous bioactive proteins in three-dimensional cultured nucleus pulposus cells of herniated intervertebral discs: identification of potential target proteins for gene therapeutic approaches.The role of ADAMTS-7 and ADAMTS-12 in the pathogenesis of arthritis.The emerging roles of ADAMTS-7 and ADAMTS-12 matrix metalloproteinases.
P2860
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P2860
Inhibition of ADAM-TS4 and ADAM-TS5 prevents aggrecan degradation in osteoarthritic cartilage.
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Inhibition of ADAM-TS4 and ADA ...... n in osteoarthritic cartilage.
@ast
Inhibition of ADAM-TS4 and ADA ...... n in osteoarthritic cartilage.
@en
Inhibition of ADAM-TS4 and ADA ...... n in osteoarthritic cartilage.
@nl
type
label
Inhibition of ADAM-TS4 and ADA ...... n in osteoarthritic cartilage.
@ast
Inhibition of ADAM-TS4 and ADA ...... n in osteoarthritic cartilage.
@en
Inhibition of ADAM-TS4 and ADA ...... n in osteoarthritic cartilage.
@nl
prefLabel
Inhibition of ADAM-TS4 and ADA ...... n in osteoarthritic cartilage.
@ast
Inhibition of ADAM-TS4 and ADA ...... n in osteoarthritic cartilage.
@en
Inhibition of ADAM-TS4 and ADA ...... n in osteoarthritic cartilage.
@nl
P2093
P2860
P356
P1476
Inhibition of ADAM-TS4 and ADA ...... n in osteoarthritic cartilage.
@en
P2093
Anne-Marie Malfait
Kosei Ijiri
Micky D Tortorella
Rui-Qin Liu
Setsuro Komiya
P2860
P304
22201-22208
P356
10.1074/JBC.M200431200
P407
P577
2002-04-15T00:00:00Z