New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.
about
Pharmacological gating modulation of small- and intermediate-conductance Ca(2+)-activated K(+) channels (KCa2.x and KCa3.1)Down-regulation of KCa2.3 channels causes erectile dysfunction in miceA novel pan-negative-gating modulator of KCa2/3 channels, fluoro-di-benzoate, RA-2, inhibits endothelium-derived hyperpolarization-type relaxation in coronary artery and produces bradycardia in vivo.Targeting the Small- and Intermediate-Conductance Ca-Activated Potassium Channels: The Drug-Binding Pocket at the Channel/Calmodulin InterfaceKCa 3.1 upregulation preserves endothelium-dependent vasorelaxation during aging and oxidative stressInhibition of Intermediate-Conductance Calcium-Activated K Channel (KCa3.1) and Fibroblast Mitogenesis by α-Linolenic Acid and Alterations of Channel Expression in the Lysosomal Storage Disorders, Fabry Disease, and Niemann Pick CRole of Calcium-activated Potassium Channels in Atrial Fibrillation Pathophysiology and Therapy.Emerging roles of calcium-activated K channels and TRPV4 channels in lung oedema and pulmonary circulatory collapse.KCa3.1 Channel Modulators as Potential Therapeutic Compounds for Glioblastoma.Vascular Reactivity Profile of Novel KCa 3.1-Selective Positive-Gating Modulators in the Coronary Vascular Bed.Differential Kv1.3, KCa3.1, and Kir2.1 expression in "classically" and "alternatively" activated microglia.Blood-brain barrier KCa3.1 channels: evidence for a role in brain Na uptake and edema in ischemic stroke.Structural Determinants for the Selectivity of the Positive KCa3.1 Gating Modulator 5-Methylnaphtho[2,1-d]oxazol-2-amine (SKA-121).Expression and function of the small-conductance Ca2+-activated K+ channel is decreased in urinary bladder smooth muscle cells from female guinea pig with partial bladder outlet obstruction.Stabilization of protein-protein interactions in drug discovery.Pharmacologic targeting of endothelial Ca2+-activated K+ channels: A strategy to improve cardiovascular function.A multiplatform strategy for the discovery of conventional monoclonal antibodies that inhibit the voltage-gated potassium channel Kv1.3.A defect in KCa3.1 channel activity limits the ability of CD8+ T cells from cancer patients to infiltrate an adenosine-rich microenvironment.Comparing Effects of Transforming Growth Factor β1 on Microglia From Rat and Mouse: Transcriptional Profiles and Potassium Channels.
P2860
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P2860
New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.
@ast
New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.
@en
New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.
@nl
type
label
New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.
@ast
New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.
@en
New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.
@nl
prefLabel
New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.
@ast
New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.
@en
New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.
@nl
P2093
P2860
P356
P1476
New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.
@en
P2093
Brandon M Brown
Heike Wulff
Marilyn M Olmstead
Nichole Coleman
Ralf Köhler
Vikrant Singh
P2860
P304
P356
10.1124/MOL.114.093286
P577
2014-06-23T00:00:00Z