Tyrosine phosphorylation of tau accompanies disease progression in transgenic mouse models of tauopathy.
about
A phase Ib multiple ascending dose study of the safety, tolerability, and central nervous system availability of AZD0530 (saracatinib) in Alzheimer's diseaseTau and tauopathiesTyrosine phosphorylation of tau regulates its interactions with Fyn SH2 domains, but not SH3 domains, altering the cellular localization of tau.Premature lethality, hyperactivity, and aberrant phosphorylation in transgenic mice expressing a constitutively active form of Fyn.Roles of tau protein in health and disease.Tau phosphorylation induced by severe closed head traumatic brain injury is linked to the cellular prion proteinThe spleen tyrosine kinase (Syk) regulates Alzheimer amyloid-β production and Tau hyperphosphorylation.Fyn inhibition rescues established memory and synapse loss in Alzheimer mice.Tau monoclonal antibody generation based on humanized yeast models: impact on Tau oligomerization and diagnosticsFyn knock-down increases Aβ, decreases phospho-tau, and worsens spatial learning in 3×Tg-AD miceSoluble Aβ oligomer production and toxicity.The many faces of tauThe complex PrP(c)-Fyn couples human oligomeric Aβ with pathological tau changes in Alzheimer's disease.What Renders TAU ToxicSelective suppression of the α isoform of p38 MAPK rescues late-stage tau pathology.Tau protein modifications and interactions: their role in function and dysfunction.Fyn kinase inhibition as a novel therapy for Alzheimer's disease.Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology.Tau-induced neurodegeneration: mechanisms and targets.Mutations in MAPT give rise to aneuploidy in animal models of tauopathy.Targeting Fyn Kinase in Alzheimer's Disease.The Distance between N and C Termini of Tau and of FTDP-17 Mutants Is Modulated by Microtubule Interactions in Living Cells.The involvement of cholinergic neurons in the spreading of tau pathology.The NAP motif of activity-dependent neuroprotective protein (ADNP) regulates dendritic spines through microtubule end binding proteins.Synaptotoxic Signaling by Amyloid Beta Oligomers in Alzheimer's Disease Through Prion Protein and mGluR5.Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies
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P2860
Tyrosine phosphorylation of tau accompanies disease progression in transgenic mouse models of tauopathy.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Tyrosine phosphorylation of ta ...... nic mouse models of tauopathy.
@ast
Tyrosine phosphorylation of ta ...... nic mouse models of tauopathy.
@en
Tyrosine phosphorylation of ta ...... nic mouse models of tauopathy.
@nl
type
label
Tyrosine phosphorylation of ta ...... nic mouse models of tauopathy.
@ast
Tyrosine phosphorylation of ta ...... nic mouse models of tauopathy.
@en
Tyrosine phosphorylation of ta ...... nic mouse models of tauopathy.
@nl
prefLabel
Tyrosine phosphorylation of ta ...... nic mouse models of tauopathy.
@ast
Tyrosine phosphorylation of ta ...... nic mouse models of tauopathy.
@en
Tyrosine phosphorylation of ta ...... nic mouse models of tauopathy.
@nl
P2860
P1476
Tyrosine phosphorylation of ta ...... enic mouse models of tauopathy
@en
P2093
P2860
P304
P356
10.1111/J.1365-2990.2010.01103.X
P577
2010-10-01T00:00:00Z