about
One world, one womanExome sequencing and functional analysis identifies BANF1 mutation as the cause of a hereditary progeroid syndromeEpigenetics and agingDNA Damage: A Main Determinant of Vascular AgingMolecular insights into the premature aging disease progeriaThe short-lived African turquoise killifish: an emerging experimental model for ageingCardiomyocyte-specific expression of lamin a improves cardiac function in Lmna-/- miceReduced life- and healthspan in mice carrying a mono-allelic BubR1 MVA mutationSenescent stromal cells induce cancer cell migration via inhibition of RhoA/ROCK/myosin-based cell contractility.Inhibition of telomere recombination by inactivation of KEOPS subunit Cgi121 promotes cell longevity.The hallmarks of agingAge-dependent down-regulation of DNA polymerase δ1 in human lymphocytesPotential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseasesGrowth conditions that increase or decrease lifespan in Saccharomyces cerevisiae lead to corresponding decreases or increases in rates of interstitial deletions and non-reciprocal translocationsInterruption of progerin-lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotypeHuman longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studiesInterleukin-7 and Immunosenescence.Specifying peripheral heterochromatin during nuclear lamina reassembly.Anti-Aging Potentials of Methylene Blue for Human Skin Longevity.Genome-wide association study of relative telomere length.Human longevity and variation in DNA damage response and repair: study of the contribution of sub-processes using competitive gene-set analysis.Stem cell aging: mechanisms, regulators and therapeutic opportunities.Cell autonomous and systemic factors in progeria development.Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan.DNA repair defects and genome instability in Hutchinson-Gilford Progeria Syndrome.Role of SAGA in the asymmetric segregation of DNA circles during yeast ageing.In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming.Manifestations and mechanisms of stem cell aging.Biology of the Mi-2/NuRD Complex in SLAC (Stemness, Longevity/Ageing, and Cancer).Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndromeTranscriptional profiling reveals progeroid Ercc1(-/Δ) mice as a model system for glomerular aging.Generation of induced pluripotent stem cell lines from 3 distinct laminopathies bearing heterogeneous mutations in lamin A/CSome highlights of research on aging with invertebrates, 2010.Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid featuresPolμ deficiency increases resistance to oxidative damage and delays liver aging.Alzheimer's disease is not "brain aging": neuropathological, genetic, and epidemiological human studies.MicroRNA transcriptome analysis identifies miR-365 as a novel negative regulator of cell proliferation in Zmpste24-deficient mouse embryonic fibroblasts.Emerging models and paradigms for stem cell ageing.Naive T cell maintenance and function in human aging.Biological ageing and frailty markers in breast cancer patients
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
Progeria syndromes and ageing: what is the connection?
@ast
Progeria syndromes and ageing: what is the connection?
@en
Progeria syndromes and ageing: what is the connection?
@nl
type
label
Progeria syndromes and ageing: what is the connection?
@ast
Progeria syndromes and ageing: what is the connection?
@en
Progeria syndromes and ageing: what is the connection?
@nl
prefLabel
Progeria syndromes and ageing: what is the connection?
@ast
Progeria syndromes and ageing: what is the connection?
@en
Progeria syndromes and ageing: what is the connection?
@nl
P2860
P356
P1476
Progeria syndromes and ageing: what is the connection?
@en
P2093
Brian K Kennedy
Christopher R Burtner
P2860
P2888
P304
P356
10.1038/NRM2944
P577
2010-08-01T00:00:00Z
P5875
P6179
1025973418