Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
about
Rapid and highly efficient generation of induced pluripotent stem cells from human umbilical vein endothelial cellsProgressive degeneration of human neural stem cells caused by pathogenic LRRK2Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cellsHallmarks of progeroid syndromes: lessons from mice and reprogrammed cellsHuman induced pluripotent stem cells for monogenic disease modelling and therapyhiPSC-derived iMSCs: NextGen MSCs as an advanced therapeutically active cell resource for regenerative medicineCardiovascular Disease Modeling Using Patient-Specific Induced Pluripotent Stem CellsMending broken hearts: cardiac development as a basis for adult heart regeneration and repairModelling human disease with pluripotent stem cellsThe genomic stability of induced pluripotent stem cellsNuclear lamins and oxidative stress in cell proliferation and longevityProgramming and Reprogramming Cellular Age in the Era of Induced PluripotencymiR-9: the sentinel of neurons in progeriaHeterochromatin formation promotes longevity and represses ribosomal RNA synthesisClinical applications of patient-specific induced pluripotent stem cells in cardiovascular medicine.Recent advances in animal and human pluripotent stem cell modeling of cardiac laminopathyUsing VAAST to identify an X-linked disorder resulting in lethality in male infants due to N-terminal acetyltransferase deficiencyRepression of the Antioxidant NRF2 Pathway in Premature AgingNuclear DNA damage signalling to mitochondria in ageingMitochondrial-associated cell death mechanisms are reset to an embryonic-like state in aged donor-derived iPS cells harboring chromosomal aberrationsInterruption of progerin-lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotypeA kinase inhibitor screen identifies small-molecule enhancers of reprogramming and iPS cell generation.Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes.Robust derivation of epicardium and its differentiated smooth muscle cell progeny from human pluripotent stem cells.Visualization of aging-associated chromatin alterations with an engineered TALE system.Drug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation.Stem cell biology and drug discovery.Age-associated chromatin relaxation is enhanced in Huntington's disease mice.Oxidative stress and antioxidant response in fibroblasts from Werner and atypical Werner syndromes.Epigenetics of aging and aging-related disease.CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs.Embryonic origins of human vascular smooth muscle cells: implications for in vitro modeling and clinical applicationPrelamin A accumulation and stress conditions induce impaired Oct-1 activity and autophagy in prematurely aged human mesenchymal stem cellMechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1.DNA damage and laminsInduced Pluripotent Stem Cells: Global Research Trends.Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state.Back to the future: how human induced pluripotent stem cells will transform regenerative medicine.iPSCs as a major opportunity to understand and cure age-related diseases.DNA-damage accumulation and replicative arrest in Hutchinson-Gilford progeria syndrome
P2860
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P2860
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
@ast
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
@en
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
@nl
type
label
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
@ast
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
@en
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
@nl
prefLabel
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
@ast
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
@en
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
@nl
P2093
P2860
P4510
P50
P356
P1433
P1476
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
@en
P2093
Athanasia D Panopoulos
Basam Z Barkho
Christopher Walsh
Guang-Hui Liu
Ho Lim Fung
James Thompson
John Yates
Keiichiro Suzuki
P2860
P2888
P304
P356
10.1038/NATURE09879
P407
P577
2011-02-23T00:00:00Z