about
The adenovirus E1A oncoprotein recruits the cellular TRRAP/GCN5 histone acetyltransferase complexUse of adenoviral E1A protein to analyze K18 promoter deregulation in colon carcinoma cells discloses a role for CtBP1 and BRCA1.Use of altered-specificity binding Oct-4 suggests an absence of pluripotent cell-specific cofactor usageGoing viral: a review of replication-selective oncolytic adenovirusesMatrix and backstage: cellular substrates for viral vaccinesStructural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoproteinThe adaptor protein DCAF7 mediates the interaction of the adenovirus E1A oncoprotein with the protein kinases DYRK1A and HIPK2E1A activates transcription of p73 and Noxa to induce apoptosisAdenovirus-mediated sensitization to the cytotoxic drugs docetaxel and mitoxantrone is dependent on regulatory domains in the E1ACR1 gene-regionMechanisms of pathogenesis of emerging adenoviruses.Adenovirus protein VII condenses DNA, represses transcription, and associates with transcriptional activator E1A.Grainyhead-like 2 inhibits the coactivator p300, suppressing tubulogenesis and the epithelial-mesenchymal transition.An improved genetic system for detection and analysis of protein nuclear import signals.Genomic and bioinformatics analysis of human adenovirus type 37: new insights into corneal tropism.Requirements for E1A dependent transcription in the yeast Saccharomyces cerevisiae.Use of tissue-specific microRNA to control pathology of wild-type adenovirus without attenuation of its ability to kill cancer cellsComplex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300.E1A and a nuclear receptor corepressor splice variant (N-CoRI) are thyroid hormone receptor coactivators that bind in the corepressor mode.The adenovirus E4-6/7 protein directs nuclear localization of E2F-4 via an arginine-rich motif.Oncolytic Viruses for Cancer Therapy: Overcoming the Obstacles.Downregulation of microRNA miR-520h by E1A contributes to anticancer activity.Adenovirus 5 E1A enhances histone deacetylase inhibitors-induced apoptosis through Egr-1-mediated Bim upregulationRecent lessons in gene expression, cell cycle control, and cell biology from adenovirus.hTERT extends the life of human fibroblasts without compromising type I interferon signaling.Adenovirus E1A proteins direct subcellular redistribution of Nek9, a NimA-related kinase.The high-risk HPV16 E7 oncoprotein mediates interaction between the transcriptional coactivator CBP and the retinoblastoma protein pRb.Downmodulation of E1A protein expression as a novel strategy to design cancer-selective adenoviruses.Viral retasking of hBre1/RNF20 to recruit hPaf1 for transcriptional activation.C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs.Inducible nitric oxide synthase expression inhibition by adenovirus E1A.Emerging roles of DNA tumor viruses in cell proliferation: new insights into genomic instability.Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation.FOXO3a-Dependent Mechanism of E1A-Induced Chemosensitization.The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases.Upstream AP1- and CREB-binding sites confer high basal activity on the adeno-associated virus type 5 capsid gene promoterTransforming growth factor beta1 receptor II is downregulated by E1A in adenovirus-infected cellsAdenovirus type 5 exerts genome-wide control over cellular programs governing proliferation, quiescence, and survival.Viral oncoproteins target the DNA methyltransferases.Viruses - seeking and destroying the tumor program.Inactivating intracellular antiviral responses during adenovirus infection.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Adenovirus-5 E1A: paradox and paradigm.
@ast
Adenovirus-5 E1A: paradox and paradigm.
@en
Adenovirus-5 E1A: paradox and paradigm.
@nl
type
label
Adenovirus-5 E1A: paradox and paradigm.
@ast
Adenovirus-5 E1A: paradox and paradigm.
@en
Adenovirus-5 E1A: paradox and paradigm.
@nl
prefLabel
Adenovirus-5 E1A: paradox and paradigm.
@ast
Adenovirus-5 E1A: paradox and paradigm.
@en
Adenovirus-5 E1A: paradox and paradigm.
@nl
P356
P1476
Adenovirus-5 E1A: paradox and paradigm.
@en
P2093
Joe S Mymryk
Steven M Frisch
P2888
P304
P356
10.1038/NRM827
P577
2002-06-01T00:00:00Z
P6179
1040445267