Tailoring the pharmacokinetics and positron emission tomography imaging properties of anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments.
about
Metabolic biotinylation of recombinant antibody by biotin ligase retained in the endoplasmic reticulumMapping biological behaviors by application of longer-lived positron emitting radionuclidesQuantitative whole body biodistribution of fluorescent-labeled agents by non-invasive tomographic imagingUnexpected expression pattern for glycosylphosphatidylinositol-anchored HDL-binding protein 1 (GPIHBP1) in mouse tissues revealed by positron emission tomography scanning.Development of radioimmunotherapeutic and diagnostic antibodies: an inside-out view.A modular IgG-scFv bispecific antibody topology.Recombinant carcinoembryonic antigen as a reporter gene for molecular imagingEffect of antigen turnover rate and expression level on antibody penetration into tumor spheroids.ImmunoPET imaging of B-cell lymphoma using 124I-anti-CD20 scFv dimers (diabodies).Recombinant anti-CD20 antibody fragments for small-animal PET imaging of B-cell lymphomas.Development of 124I immuno-PET targeting tumor vascular TEM1/endosialin.Fusion protein of single-chain variable domain fragments for treatment of myasthenia gravis.Tuning the serum persistence of human serum albumin domain III:diabody fusion proteins.Optimizing radiolabeled engineered anti-p185HER2 antibody fragments for in vivo imaging.Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor.Neonatal Fc receptor: from immunity to therapeuticsDevelopment, optimization, and validation of novel anti-TEM1/CD248 affinity agent for optical imaging in cancerEvaluation of two internalizing carcinoembryonic antigen reporter genes for molecular imagingA method of image registration for small animal, multi-modality imagingCo-opting biology to deliver drugsMonte Carlo simulations of absorbed dose in a mouse phantom from 18-fluorine compounds.A mutated anti-CA19-9 scFv-Fc for positron emission tomography of human pancreatic cancer xenografts.Improved modeling of in vivo kinetics of slowly diffusing radiotracers for tumor imaging.Side-by-Side Comparison of Commonly Used Biomolecules That Differ in Size and Affinity on Tumor Uptake and Internalization.A fully human scFv phage display library for rapid antibody fragment reformattingRecent trends in antibody-based oncologic imagingTargeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody FragmentImmunotoxins constructed with chimeric, short-lived anti-CD22 monoclonal antibodies induce less vascular leak without loss of cytotoxicity.Improved tumor imaging and therapy via i.v. IgG-mediated time-sequential modulation of neonatal Fc receptor.Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-lifeAdvances in immuno-positron emission tomography: antibodies for molecular imaging in oncologyEngineering anti-Lewis-Y hu3S193 antibodies with improved therapeutic ratio for radioimmunotherapy of epithelial cancersPharmacokinetic properties of IgG and various Fc fusion proteins in mice.Cross-species analysis of Fc engineered anti-Lewis-Y human IgG1 variants in human neonatal receptor transgenic mice reveal importance of S254 and Y436 in binding human neonatal Fc receptor.Antibody tumor penetration: transport opposed by systemic and antigen-mediated clearance.Humanized radioiodinated minibody for imaging of prostate stem cell antigen-expressing tumorsEvaluation of an anti-p185(HER2) (scFv-C(H)2-C(H)3)2 fragment following radioiodination using two different residualizing labels: SGMIB and IB-Mal-D-GEEEK.Cerenkov Luminescence Imaging as a Modality to Evaluate Antibody-Based PET Radiotracers.Using a single parameter to describe time-activity curvesChapter 4: Multitasking by exploitation of intracellular transport functions the many faces of FcRn.
P2860
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P2860
Tailoring the pharmacokinetics and positron emission tomography imaging properties of anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Tailoring the pharmacokinetics ...... hain Fv-Fc antibody fragments.
@ast
Tailoring the pharmacokinetics ...... hain Fv-Fc antibody fragments.
@en
Tailoring the pharmacokinetics ...... hain Fv-Fc antibody fragments.
@nl
type
label
Tailoring the pharmacokinetics ...... hain Fv-Fc antibody fragments.
@ast
Tailoring the pharmacokinetics ...... hain Fv-Fc antibody fragments.
@en
Tailoring the pharmacokinetics ...... hain Fv-Fc antibody fragments.
@nl
prefLabel
Tailoring the pharmacokinetics ...... hain Fv-Fc antibody fragments.
@ast
Tailoring the pharmacokinetics ...... hain Fv-Fc antibody fragments.
@en
Tailoring the pharmacokinetics ...... hain Fv-Fc antibody fragments.
@nl
P2093
P2860
P1433
P1476
Tailoring the pharmacokinetics ...... chain Fv-Fc antibody fragments
@en
P2093
Andrew A Raubitschek
Arion F Chatziioannou
David Colcher
David N Ikle
Desiree M Crow
Gobalakrishnan Sundaresan
John E Shively
Lawrence E Williams
Murugesan Subbarayan
P2860
P304
P407
P577
2005-01-01T00:00:00Z