Effect of antigen turnover rate and expression level on antibody penetration into tumor spheroids.
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Affinity and avidity in antibody-based tumor targetingImplications of receptor-mediated endocytosis and intracellular trafficking dynamics in the development of antibody drug conjugatesThe development of immunoconjugates for targeted cancer therapyAntibody Drug Conjugates: Preclinical ConsiderationsEpitope-specific mechanisms of IGF1R inhibition by ganitumabQuantitative whole body biodistribution of fluorescent-labeled agents by non-invasive tomographic imagingEffect of antigen shedding on targeted delivery of immunotoxins in solid tumors from a mathematical modelA mechanistic tumor penetration model to guide antibody drug conjugate designIdentification of internalizing human single-chain antibodies targeting brain tumor sphere cells.Quantum dot loaded immunomicelles for tumor imaging.Fusogenics: a recombinant immunotoxin-based screening platform to select internalizing tumor-specific antibody fragments.Quantitative intratumoural microdistribution and kinetics of (131)I-huA33 antibody in patients with colorectal carcinoma.Convergent potency of internalized gelonin immunotoxins across varied cell lines, antigens, and targeting moietiesThe effect of co-delivery of paclitaxel and curcumin by transferrin-targeted PEG-PE-based mixed micelles on resistant ovarian cancer in 3-D spheroids and in vivo tumors.Influence of affinity and antigen internalization on the uptake and penetration of Anti-HER2 antibodies in solid tumorsCoating Solid Lipid Nanoparticles with Hyaluronic Acid Enhances Antitumor Activity against Melanoma Stem-like Cells.Noninternalizing monoclonal antibodies are suitable candidates for 125I radioimmunotherapy of small-volume peritoneal carcinomatosisTargeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody FragmentTargeting breast cancer stem cells with HER2-specific antibodies and natural killer cells.Nanoscale drug delivery systems for enhanced drug penetration into solid tumors: current progress and opportunities.Application of PBPK modeling to predict monoclonal antibody disposition in plasma and tissues in mouse models of human colorectal cancerThe Effect of Molecular Weight, PK, and Valency on Tumor Biodistribution and Efficacy of Antibody-Based Drugs.Endocytosis and signalling: a meeting with mathematics.Dose dependence of intratumoral perivascular distribution of monoclonal antibodies.Antibody vectors for imaging.Antibody-enzyme fusion proteins for cancer therapy.Mathematical modeling of vesicle drug delivery systems 2: targeted vesicle interactions with cells, tumors, and the body.Targeted drug delivery for cancer therapy: the other side of antibodies.Internalization, Trafficking, Intracellular Processing and Actions of Antibody-Drug Conjugates.Quantitative measurement of the target-mediated internalization kinetics of biopharmaceuticalsOn-chip integrated labelling, transport and detection of tumour cells.Mathematical Based Calculation of Drug Penetration Depth in Solid Tumors.The Volume of Three-Dimensional Cultures of Cancer Cells InVitro Influences Transcriptional Profile Differences and Similarities with Monolayer Cultures and Xenografted Tumors.Concurrent quantification of multiple nanoparticle bound states.A mechanistic compartmental model for total antibody uptake in tumors.Development of unique cytotoxic chimeric antigen receptors based on human scFv targeting B7H6.Pharmacokinetic Considerations for Antibody-Drug Conjugates against Cancer.
P2860
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P2860
Effect of antigen turnover rate and expression level on antibody penetration into tumor spheroids.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Effect of antigen turnover rat ...... etration into tumor spheroids.
@ast
Effect of antigen turnover rat ...... etration into tumor spheroids.
@en
type
label
Effect of antigen turnover rat ...... etration into tumor spheroids.
@ast
Effect of antigen turnover rat ...... etration into tumor spheroids.
@en
prefLabel
Effect of antigen turnover rat ...... etration into tumor spheroids.
@ast
Effect of antigen turnover rat ...... etration into tumor spheroids.
@en
P2093
P2860
P1476
Effect of antigen turnover rat ...... etration into tumor spheroids.
@en
P2093
David Pawlowski
K Dane Wittrup
Margaret E Ackerman
P2860
P304
P356
10.1158/1535-7163.MCT-08-0067
P577
2008-07-01T00:00:00Z