Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner.
about
Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal-regulating kinase 1-JNK/p38 activationAIP1 mediates TNF-alpha-induced ASK1 activation by facilitating dissociation of ASK1 from its inhibitor 14-3-3Etk/Bmx as a tumor necrosis factor receptor type 2-specific kinase: role in endothelial cell migration and angiogenesisRedox mechanisms in hepatic chronic wound healing and fibrogenesisThioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1Thioredoxin and ventricular remodelingDownregulation of Reactive Oxygen Species in ApoptosisRedox modification of cell signaling in the cardiovascular systemApoptosis of cholangiocytes modulated by thioredoxin of carcinogenic liver fluke.The thioredoxin TRX-1 modulates the function of the insulin-like neuropeptide DAF-28 during dauer formation in Caenorhabditis elegansStructural and Functional Characterization of the Human Protein Kinase ASK1ASK1 associates with troponin T and induces troponin T phosphorylation and contractile dysfunction in cardiomyocytesInteraction of ALG-2 with ASK1 influences ASK1 localization and subsequent JNK activationHyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting proteinThioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signalingSomatic mutations in MAP3K5 attenuate its proapoptotic function in melanoma through increased binding to thioredoxinCardiac hypertrophy is associated with altered thioredoxin and ASK-1 signaling in a mouse model of menopauseCatalytic degradation of vitamin D up-regulated protein 1 mRNA enhances cardiomyocyte survival and prevents left ventricular remodeling after myocardial ischemiaTumor necrosis factor-alpha and apoptosis signal-regulating kinase 1 control reactive oxygen species release, mitochondrial autophagy, and c-Jun N-terminal kinase/p38 phosphorylation during necrotizing enterocolitisRedox regulation of tumor necrosis factor signalingFunctional significance for a heterogenous ribonucleoprotein A18 signature RNA motif in the 3'-untranslated region of ataxia telangiectasia mutated and Rad3-related (ATR) transcript.The anticancer agent chaetocin is a competitive substrate and inhibitor of thioredoxin reductase.The Role of NOX4 and TRX2 in Angiogenesis and Their Potential Cross-Talk.C-terminus of heat shock protein 70-interacting protein facilitates degradation of apoptosis signal-regulating kinase 1 and inhibits apoptosis signal-regulating kinase 1-dependent apoptosis.Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila.Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell deathMinireview: Thioredoxin-interacting protein: regulation and function in the pancreatic β-cell.Methylglyoxal increases cardiomyocyte ischemia-reperfusion injury via glycative inhibition of thioredoxin activity.Obligatory role of ASK1 in the apoptotic surge of K+ currents.Inhibition of endogenous thioredoxin in the heart increases oxidative stress and cardiac hypertrophy.The ASK1-Signalosome regulates p38 MAPK activity in response to levels of endogenous oxidative stress in the Klotho mouse models of aging.Protein phosphatase 4 is a positive regulator of hematopoietic progenitor kinase 1.Role of apoptosis signal-regulating kinase-1-c-Jun NH2-terminal kinase-p38 signaling in voltage-gated K+ channel remodeling of the failing heart: regulation by thioredoxin.Modulation of signaling mechanisms in the heart by thioredoxin 1.SENP1 mediates TNF-induced desumoylation and cytoplasmic translocation of HIPK1 to enhance ASK1-dependent apoptosis.Expression of thioredoxin-1 and hypoxia inducible factor-1α in cerebral arteriovenous malformations: Possible role of redox regulatory factor in neoangiogenic propertyThe interaction of thioredoxin with Txnip. Evidence for formation of a mixed disulfide by disulfide exchange.The emerging role of the thioredoxin system in angiogenesisGlutathione and apoptosis.Redox regulation of cell growth and cell death.
P2860
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P2860
Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Thioredoxin promotes ASK1 ubiq ...... x activity-independent manner.
@ast
Thioredoxin promotes ASK1 ubiq ...... x activity-independent manner.
@en
Thioredoxin promotes ASK1 ubiq ...... x activity-independent manner.
@nl
type
label
Thioredoxin promotes ASK1 ubiq ...... x activity-independent manner.
@ast
Thioredoxin promotes ASK1 ubiq ...... x activity-independent manner.
@en
Thioredoxin promotes ASK1 ubiq ...... x activity-independent manner.
@nl
prefLabel
Thioredoxin promotes ASK1 ubiq ...... x activity-independent manner.
@ast
Thioredoxin promotes ASK1 ubiq ...... x activity-independent manner.
@en
Thioredoxin promotes ASK1 ubiq ...... x activity-independent manner.
@nl
P1433
P1476
Thioredoxin promotes ASK1 ubiq ...... x activity-independent manner.
@en
P2093
P304
P356
10.1161/01.RES.0000022160.64355.62
P577
2002-06-01T00:00:00Z