CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.
about
Multi-state modeling of biomoleculesIdentifying Individual T Cell Receptors of Optimal Avidity for Tumor AntigensLower Affinity T Cells are Critical Components and Active Participants of the Immune ResponseThe multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cellsT cell antigen recognition at the cell membraneCrystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4Recent advances in T-cell engineering for use in immunotherapyT cell receptor bias for MHC: co-evolution or co-receptors?Systems biology. Conditional density-based analysis of T cell signaling in single-cell data.Novel tools to dissect the dynamic regulation of TCR signaling by the kinase Csk and the phosphatase CD45Contribution of TCR signaling strength to CD8+ T cell peripheral tolerance mechanismsHow the immune system talks to itself: the varied role of synapsesProtein clusters on the T cell surface may suppress spurious early signaling events.Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptorSignaling in thymic selection.Interaction of streptavidin-based peptide-MHC oligomers (tetramers) with cell-surface TCRsCD8αα and -αβ isotypes are equally recruited to the immunological synapse through their ability to bind to MHC class I.The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway.TCR affinity and specificity requirements for human regulatory T-cell functionA computational model for early events in B cell antigen receptor signaling: analysis of the roles of Lyn and Fyn.Psychological stress and aging: role of glucocorticoids (GCs)Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactionsIdentification of the dichotomous role of age-related LCK in calorie restriction revealed by integrative analysis of cDNA microarray and interactomeStructural and biophysical insights into the role of CD4 and CD8 in T cell activation.Constitutive Lck Activity Drives Sensitivity Differences between CD8+ Memory T Cell Subsets.Role of T cell receptor affinity in the efficacy and specificity of adoptive T cell therapies.Coreceptor affinity for MHC defines peptide specificity requirements for TCR interaction with coagonist peptide-MHC.Phosphorylation of a Tyrosine Residue on Zap70 by Lck and Its Subsequent Binding via an SH2 Domain May Be a Key Gatekeeper of T Cell Receptor Signaling In Vivo.Insights into the initiation of TCR signaling.2D TCR-pMHC-CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system.Rule-based modeling: a computational approach for studying biomolecular site dynamics in cell signaling systems.New insights into the T cell synapse from single molecule techniques.Structural basis for self-recognition by autoimmune T-cell receptors.The structural basis of αβ T-lineage immune recognition: TCR docking topologies, mechanotransduction, and co-receptor function.Signaling in lymphocyte activation.Adoptive T Cell Therapies: A Comparison of T Cell Receptors and Chimeric Antigen ReceptorsMathematical Models for Immunology: Current State of the Art and Future Research Directions.Relative Movements of Domains in Large Molecules of the Immune System.Coreceptor scanning by the T cell receptor provides a mechanism for T cell tolerance.Lck, Membrane Microdomains, and TCR Triggering Machinery: Defining the New Rules of Engagement
P2860
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P2860
CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.
@ast
CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.
@en
CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.
@nl
type
label
CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.
@ast
CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.
@en
CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.
@nl
prefLabel
CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.
@ast
CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.
@en
CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.
@nl
P2093
P2860
P356
P1476
CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.
@en
P2093
Arup K Chakraborty
Mark M Davis
Maxim N Artyomov
Mieszko Lis
Srinivas Devadas
P2860
P304
16916-16921
P356
10.1073/PNAS.1010568107
P407
P577
2010-09-13T00:00:00Z