CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery. - Wikidata - awgldk - TriplyDB

CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.

CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.

http://www.wikidata.org/entity/Q34137733

about

Multi-state modeling of biomolecules Identifying Individual T Cell Receptors of Optimal Avidity for Tumor Antigens Lower Affinity T Cells are Critical Components and Active Participants of the Immune Response The multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cells T cell antigen recognition at the cell membrane Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4 Recent advances in T-cell engineering for use in immunotherapy T cell receptor bias for MHC: co-evolution or co-receptors?Systems biology. Conditional density-based analysis of T cell signaling in single-cell data.Novel tools to dissect the dynamic regulation of TCR signaling by the kinase Csk and the phosphatase CD45 Contribution of TCR signaling strength to CD8+ T cell peripheral tolerance mechanisms How the immune system talks to itself: the varied role of synapses Protein clusters on the T cell surface may suppress spurious early signaling events.Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor Signaling in thymic selection.Interaction of streptavidin-based peptide-MHC oligomers (tetramers) with cell-surface TCRs CD8αα and -αβ isotypes are equally recruited to the immunological synapse through their ability to bind to MHC class I.The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway.TCR affinity and specificity requirements for human regulatory T-cell function A computational model for early events in B cell antigen receptor signaling: analysis of the roles of Lyn and Fyn.Psychological stress and aging: role of glucocorticoids (GCs)Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions Identification of the dichotomous role of age-related LCK in calorie restriction revealed by integrative analysis of cDNA microarray and interactome Structural and biophysical insights into the role of CD4 and CD8 in T cell activation.Constitutive Lck Activity Drives Sensitivity Differences between CD8+ Memory T Cell Subsets.Role of T cell receptor affinity in the efficacy and specificity of adoptive T cell therapies.Coreceptor affinity for MHC defines peptide specificity requirements for TCR interaction with coagonist peptide-MHC.Phosphorylation of a Tyrosine Residue on Zap70 by Lck and Its Subsequent Binding via an SH2 Domain May Be a Key Gatekeeper of T Cell Receptor Signaling In Vivo.Insights into the initiation of TCR signaling.2D TCR-pMHC-CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system.Rule-based modeling: a computational approach for studying biomolecular site dynamics in cell signaling systems.New insights into the T cell synapse from single molecule techniques.Structural basis for self-recognition by autoimmune T-cell receptors.The structural basis of αβ T-lineage immune recognition: TCR docking topologies, mechanotransduction, and co-receptor function.Signaling in lymphocyte activation.Adoptive T Cell Therapies: A Comparison of T Cell Receptors and Chimeric Antigen Receptors Mathematical Models for Immunology: Current State of the Art and Future Research Directions.Relative Movements of Domains in Large Molecules of the Immune System.Coreceptor scanning by the T cell receptor provides a mechanism for T cell tolerance.Lck, Membrane Microdomains, and TCR Triggering Machinery: Defining the New Rules of Engagement

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P2860

CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.

http://www.wikidata.org/entity/Q34137733

description

2010 nî lūn-bûn

@nan

2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

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name

CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.

@ast

CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.

@en

CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.

@nl

type

label

CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.

@ast

CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.

@en

CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.

@nl

prefLabel

CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.

@ast

CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.

@en

CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.

@nl

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PNAS.1010568107

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.

@en

P2093

Arup K Chakraborty

http://www.w3.org/2001/XMLSchema#string

Mark M Davis

http://www.w3.org/2001/XMLSchema#string

Maxim N Artyomov

http://www.w3.org/2001/XMLSchema#string

Mieszko Lis

http://www.w3.org/2001/XMLSchema#string

Srinivas Devadas

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P2860

Modeling T cell antigen discrimination based on feedback control of digital ERK responses

The immunological synapse: a molecular machine controlling T cell activation

Stochastic reaction-diffusion simulation with MesoRD.

Effects of intracellular calcium and actin cytoskeleton on TCR mobility measured by fluorescence recovery.

Differences in antigen recognition and cytolytic activity of CD8(+) and CD8(-) T cells that express the same antigen-specific receptor.

Molecular coordination of alphabeta T-cell receptors and coreceptors CD8 and CD4 in their recognition of peptide-MHC ligands.

Digital signaling and hysteresis characterize ras activation in lymphoid cells.

Rule-based modeling of biochemical systems with BioNetGen.

Efficient stochastic simulation of reaction-diffusion processes via direct compilation

Sensitivity of T cells to antigen and antagonism emerges from differential regulation of the same molecular signaling module.

P304

16916-16921

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scholarly article

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10.1073/PNAS.1010568107

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39

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107

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2010-09-13T00:00:00Z

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46255506

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20837541

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2947881

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