The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex.

The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex.

Item
http://www.wikidata.org/entity/Q34139710
A HECT ubiquitin-protein ligase as a novel candidate gene for altered quinine and quinidine responses in Plasmodium falciparumBayesian models trained with HTS data for predicting β-haematin inhibition and in vitro antimalarial activity.Mutation in the Plasmodium falciparum CRT protein determines the stereospecific activity of antimalarial cinchona alkaloids.Quinolines block every step of malaria heme crystal growth.Deconstructing Quinoline-Class Antimalarials to Identify Fundamental Physicochemical Properties of Beta-Hematin Crystal Growth Inhibitors.Cytostatic versus cytocidal activities of chloroquine analogues and inhibition of hemozoin crystal growth.Relative to quinine and quinidine, their 9-epimers exhibit decreased cytostatic activity and altered heme binding but similar cytocidal activity versus Plasmodium falciparum.Interactions between artemisinins and other antimalarial drugs in relation to the cofactor model--a unifying proposal for drug action.Investigating the activity of quinine analogues versus chloroquine resistant Plasmodium falciparum.Quinine localizes to a non-acidic compartment within the food vacuole of the malaria parasite Plasmodium falciparum.Shining new light on ancient drugs: preparation and subcellular localisation of novel fluorescent analogues of Cinchona alkaloids in intraerythrocytic Plasmodium falciparum.Alkoxide coordination of iron(III) protoporphyrin IX by antimalarial quinoline methanols: a key interaction observed in the solid-state and solution.Design and synthesis of a 4-aminoquinoline-based molecular tweezer that recognizes protoporphyrin IX and iron(iii) protoporphyrin IX and its application as a supramolecular photosensitizer
P2860

The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex.

Item
http://www.wikidata.org/entity/Q34139710
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The hydroxyl functionality and ...... covalent quinine-heme complex.
@ast
The hydroxyl functionality and ...... covalent quinine-heme complex.
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The hydroxyl functionality and ...... covalent quinine-heme complex.
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type
label
The hydroxyl functionality and ...... covalent quinine-heme complex.
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The hydroxyl functionality and ...... covalent quinine-heme complex.
@en
The hydroxyl functionality and ...... covalent quinine-heme complex.
@nl
prefLabel
The hydroxyl functionality and ...... covalent quinine-heme complex.
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The hydroxyl functionality and ...... covalent quinine-heme complex.
@en
The hydroxyl functionality and ...... covalent quinine-heme complex.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
The hydroxyl functionality and ...... -covalent quinine-heme complex
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P2093
P2860
P304
P31
P356
10.1016/J.JINORGBIO.2010.08.011
P433
P478
P50
P577
P5875
P698
P932