GABA acts as a ligand chaperone in the early secretory pathway to promote cell surface expression of GABAA receptors
about
Pharmacological chaperoning: a primer on mechanism and pharmacologyUsing pharmacological chaperones to restore proteostasisGABAA receptor trafficking-mediated plasticity of inhibitory synapses.Neuronal gamma-aminobutyric acid (GABA) type A receptors undergo cognate ligand chaperoning in the endoplasmic reticulum by endogenous GABA.Chaperoning of the A1-adenosine receptor by endogenous adenosine - an extension of the retaliatory metabolite concept.Agonist- and antagonist-induced up-regulation of surface 5-HT3 A receptors.Regulation of the surface expression of α4β2δ GABAA receptors by high efficacy statesFlumazenil decreases surface expression of α4β2δ GABAA receptors by increasing the rate of receptor internalizationThe stress-induced cytokine interleukin-6 decreases the inhibition/excitation ratio in the rat temporal cortex via trans-signaling.Conduits of life's spark: a perspective on ion channel research since the birth of neuron.SAHA enhances Proteostasis of epilepsy-associated α1(A322D)β2γ2 GABA(A) receptors.Pharmacological folding chaperones act as allosteric ligands of Frizzled4.BIG1, a brefeldin A-inhibited guanine nucleotide-exchange factor, is required for GABA-gated Cl⁻ influx through regulation of GABAA receptor trafficking.Pharmacological Chaperones of the Dopamine Transporter Rescue Dopamine Transporter Deficiency Syndrome Mutations in Heterologous Cells.Assembly, trafficking and function of α1β2γ2 GABAA receptors are regulated by N-terminal regions, in a subunit-specific manner.Cognate Ligand Chaperoning: a Novel Mechanism for the Post-translational Regulation of Neurotransmitter Receptor Biogenesis.A clickable neurosteroid photolabel reveals selective Golgi compartmentalization with preferential impact on proximal inhibitionThree epilepsy-associated GABRG2 missense mutations at the γ+/β- interface disrupt GABAA receptor assembly and trafficking by similar mechanisms but to different extents.Pharmacological Chaperones: Beyond Conformational Disorders.GABA type a receptor trafficking and the architecture of synaptic inhibition.Distribution and quantitative detection of GABAA receptor in Carassius auratus gibelio.2Bs or not 2Bs: that is the question.
P2860
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P2860
GABA acts as a ligand chaperone in the early secretory pathway to promote cell surface expression of GABAA receptors
description
2010 nî lūn-bûn
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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
GABA acts as a ligand chaperon ...... expression of GABAA receptors
@ast
GABA acts as a ligand chaperon ...... expression of GABAA receptors
@en
GABA acts as a ligand chaperon ...... expression of GABAA receptors
@nl
type
label
GABA acts as a ligand chaperon ...... expression of GABAA receptors
@ast
GABA acts as a ligand chaperon ...... expression of GABAA receptors
@en
GABA acts as a ligand chaperon ...... expression of GABAA receptors
@nl
prefLabel
GABA acts as a ligand chaperon ...... expression of GABAA receptors
@ast
GABA acts as a ligand chaperon ...... expression of GABAA receptors
@en
GABA acts as a ligand chaperon ...... expression of GABAA receptors
@nl
P2093
P2860
P1433
P1476
GABA acts as a ligand chaperon ...... expression of GABAA receptors
@en
P2093
Letha D Stahl
Lucy C Robinson
Nancy J Leidenheimer
Randa S Eshaq
Randolph Stone
P2860
P356
10.1016/J.BRAINRES.2010.05.030
P407
P577
2010-05-16T00:00:00Z