IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C. - Wikidata - awgldk - TriplyDB

IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C.

IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C.

http://www.wikidata.org/entity/Q34142463

about

IFNL3 mRNA structure is remodeled by a functional non-coding polymorphism associated with hepatitis C virus clearance A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus Interferon-λ: Immune Functions at Barrier Surfaces and Beyond Regulation of hepatic innate immunity by hepatitis C virus Natural killer cell responses during viral infections: flexibility and conditioning of innate immunity by experience Immune responses to HCV and other hepatitis viruses STAT proteins - key regulators of anti-viral responses, inflammation, and tumorigenesis in the liver Emerging concepts in immunity to hepatitis C virus infection.Genetic variants at the IFNL3 locus and their association with hepatitis C virus infections reveal novel insights into host-virus interactions Innate immune responses in hepatitis C virus infection The Role of Interferon Lambda 3 Genetic Polymorphisms in Response to Interferon Therapy in Chronic Hepatitis B Patients: An Updated Meta-Analysis Interferon-λ4 is a cell-autonomous type III interferon associated with pre-treatment hepatitis C virus burden Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a cross-sectional European cohort Relation of IL28B gene polymorphism with biochemical and histological features in hepatitis C virus-induced liver disease Sequence analysis of the IL28A/IL28B inverted gene duplication that contains polymorphisms associated with treatment response in hepatitis C patients Pharmacogenetics of hepatitis C: transition from interferon-based therapies to direct-acting antiviral agents Ex vivo induction of IFN-λ3 by a TLR7 agonist determines response to Peg-IFN/ribavirin therapy in chronic hepatitis C patients.Natural killer KIR3DS1 is closely associated with HCV viral clearance and sustained virological response in HIV/HCV patients microRNA-122 abundance in hepatocellular carcinoma and non-tumor liver tissue from Japanese patients with persistent HCV versus HBV infection.Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients.IFN-λ receptor 1 expression is induced in chronic hepatitis C and correlates with the IFN-λ3 genotype and with nonresponsiveness to IFN-α therapies IFNL3/4 genotype is associated with altered immune cell populations in peripheral blood in chronic hepatitis C infection Involvement of MAP3K8 and miR-17-5p in poor virologic response to interferon-based combination therapy for chronic hepatitis C.Interferon lambda polymorphisms associate with body iron indices and hepatic expression of interferon-responsive long non-coding RNA in chronic hepatitis C.Expression of selected genes in liver biopsy specimens in relation to early virological response in patients with chronic hepatitis C with HCV mono- and HIV/HCV co-infection.Zinc is a potent and specific inhibitor of IFN-λ3 signalling.Direct-acting antiviral agents and the path to interferon independence.Protective immunity against hepatitis C: many shades of gray.IL28B SNP rs12979860 is a critical predictor for on-treatment and sustained virologic response in patients with hepatitis C virus genotype-1 infection Reduction of microRNA 122 expression in IFNL3 CT/TT carriers and during progression of fibrosis in patients with chronic hepatitis C Interferon lambda alleles predict innate antiviral immune responses and hepatitis C virus permissiveness Characterization of serum proteins associated with IL28B genotype among patients with chronic hepatitis C.USP18-based negative feedback control is induced by type I and type III interferons and specifically inactivates interferon α response.An interferon response gene signature is associated with the therapeutic response of hepatitis C patients An integrated approach identifies IFN-regulated microRNAs and targeted mRNAs modulated by different HCV replicon clones IL28B alleles exert an additive dose effect when applied to HCV-HIV coinfected persons undergoing peginterferon and ribavirin therapy Hepatic STAT1-nuclear translocation and interleukin 28B polymorphisms predict treatment outcomes in hepatitis C virus genotype 1-infected patients.Genetic variations in IL28B and allergic disease in children.Circulating sCD14 is associated with virological response to pegylated-interferon-alpha/ribavirin treatment in HIV/HCV co-infected patients Immune control and failure in HCV infection--tipping the balance.

P2860

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P2860

IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C.

http://www.wikidata.org/entity/Q34142463

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2010 nî lūn-bûn

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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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Alexander J Thompson

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Alexander McKenzie

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David B Goldstein

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Detlef Schuppan

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John G McHutchison

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Kenneth D Cronin

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Kevin V Shianna

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Keyur Patel

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Linda Hong

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Shelton S Bradrick

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P2860

Human ficolin: cDNA cloning, demonstration of peripheral blood leucocytes as the major site of synthesis and assignment of the gene to chromosome 9

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

Efficient Replication of Hepatitis C Virus Genotype 1a RNAs in Cell Culture

Plasma chemokine levels correlate with the outcome of antiviral therapy in patients with hepatitis C

Interferon signaling and treatment outcome in chronic hepatitis C

Lack of response to exogenous interferon-α in the liver of chimpanzees chronically infected with hepatitis C virus

Interferon-inducible antiviral effectors

Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study

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1888-1896

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10.1002/HEP.23912

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6

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52

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