Metal-based drugs for malaria, trypanosomiasis and leishmaniasis: recent achievements and perspectives.
about
A gold-containing drug against parasitic polyamine metabolism: the X-ray structure of trypanothione reductase from Leishmania infantum in complex with auranofin reveals a dual mechanism of enzyme inhibitionGold compounds as therapeutic agents for human diseasesSynthesis and antimalarial activity of metal complexes of cross-bridged tetraazamacrocyclic ligands.New organoruthenium complexes with bioactive thiosemicarbazones as co-ligands: potential anti-trypanosomal agents.Searching for new chemotherapies for tropical diseases: ruthenium-clotrimazole complexes display high in vitro activity against Leishmania major and Trypanosoma cruzi and low toxicity toward normal mammalian cells.Metal-drug synergy: new ruthenium(II) complexes of ketoconazole are highly active against Leishmania major and Trypanosoma cruzi and nontoxic to human or murine normal cellsTargeted therapy vs. DNA-adduct formation-guided design: thoughts about the future of metal-based anticancer drugs.Gold complexes as antimicrobial agents: an overview of different biological activities in relation to the oxidation state of the gold ion and the ligand structure.Mutual action of anticancer and antiparasitic drugs: are there any shared targets?Efficacy of a Binuclear Cyclopalladated Compound Therapy for Cutaneous Leishmaniasis in the Murine Model of Infection with Leishmania amazonensis and Its Inhibitory Effect on Topoisomerase 1B.Organometallic gold(iii) complexes with hybrid SNS-donating thiosemicarbazone ligands: cytotoxicity and anti-Trypanosoma cruzi activity.A new oxidovanadium(IV) complex of oxodiacetic acid and dppz: spectroscopic and DFT study. Antitumor action on MG-63 human osteosarcoma cell line.Screening organometallic binuclear thiosemicarbazone ruthenium complexes as potential anti-tumour agents: cytotoxic activity and human serum albumin binding mechanism.Potential cytotoxic and amoebicide activity of first row transition metal compounds with 2,9-bis-(2',5'-diazahexanyl)-1,1-phenanthroline (L1).Synthesis and biological activity of cymantrene and cyrhetrene 4-aminoquinoline conjugates against malaria, leishmaniasis, and trypanosomiasis.Ruthenium-Clotrimazole complex has significant efficacy in the murine model of cutaneous leishmaniasis.Aromatic amine N-oxide organometallic compounds: searching for prospective agents against infectious diseases.Copper(ii) mixed-ligand polypyridyl complexes with doxycycline - structures and biological evaluation.The ferroquine antimalarial conundrum: redox activation and reinvasion inhibition.A new series of heteroleptic oxidovanadium(IV) compounds with phenanthroline-derived co-ligands: selective Trypanosoma cruzi growth inhibitors.5-Nitroisatin-derived thiosemicarbazones: potential antileishmanial agents.Organometallic Derivatization of the Nematocidal Drug Monepantel Leads to Promising Antiparasitic Drug Candidates.Potential mechanism of the anti-trypanosomal activity of organoruthenium complexes with bioactive thiosemicarbazones.DMSO-mediated ligand dissociation: renaissance for biological activity of N-heterocyclic-[Ru(η6-arene)Cl2] drug candidates.Ensemble-based ADME-Tox profiling and virtual screening for the discovery of new inhibitors of the Leishmania mexicana cysteine protease CPB2.8ΔCTE.Metals in fungal virulence.Water-soluble ruthenium complexes bearing activity against protozoan parasites.Antileishmanial, DNA Interaction, and Docking Studies of Some Ferrocene-Based Heteroleptic Pentavalent Antimonials.Gallium(iii) and iron(iii) complexes of quinolone antimicrobials.A new ruthenium cyclopentadienyl azole compound with activity on tumor cell lines and trypanosomatid parasites
P2860
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P2860
Metal-based drugs for malaria, trypanosomiasis and leishmaniasis: recent achievements and perspectives.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Metal-based drugs for malaria, ...... achievements and perspectives.
@ast
Metal-based drugs for malaria, ...... achievements and perspectives.
@en
Metal-based drugs for malaria, ...... achievements and perspectives.
@nl
type
label
Metal-based drugs for malaria, ...... achievements and perspectives.
@ast
Metal-based drugs for malaria, ...... achievements and perspectives.
@en
Metal-based drugs for malaria, ...... achievements and perspectives.
@nl
prefLabel
Metal-based drugs for malaria, ...... achievements and perspectives.
@ast
Metal-based drugs for malaria, ...... achievements and perspectives.
@en
Metal-based drugs for malaria, ...... achievements and perspectives.
@nl
P1433
P1476
Metal-based drugs for malaria, ...... achievements and perspectives.
@en
P2093
Dinorah Gambino
Maribel Navarro
P304
P356
10.1016/J.DRUDIS.2010.10.005
P577
2010-10-23T00:00:00Z