Metal-drug synergy: new ruthenium(II) complexes of ketoconazole are highly active against Leishmania major and Trypanosoma cruzi and nontoxic to human or murine normal cells
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Ruthenium complex with benznidazole and nitric oxide as a new candidate for the treatment of chagas diseaseNitro/nitrosyl-ruthenium complexes are potent and selective anti-Trypanosoma cruzi agents causing autophagy and necrotic parasite deathTherapeutical approaches under investigation for treatment of Chagas disease.Toward organometallic antischistosomal drug candidates.Organometallic gold(iii) complexes with hybrid SNS-donating thiosemicarbazone ligands: cytotoxicity and anti-Trypanosoma cruzi activity.Analysis of the cytotoxic effects of ruthenium-ketoconazole and ruthenium-clotrimazole complexes on cancer cells.Ruthenium-Clotrimazole complex has significant efficacy in the murine model of cutaneous leishmaniasis.Novel arylalkylamine compounds exhibits potent selective antiparasitic activity against Leishmania major.Organometallic Derivatization of the Nematocidal Drug Monepantel Leads to Promising Antiparasitic Drug Candidates.Transition metal complexes with bioactive ligands: mechanisms for selective ligand release and applications for drug delivery.Glycosylated metal chelators as anti-parasitic agents with tunable selectivity.In vitro effects of binuclear (η (6)-p-cymene)ruthenium(II) complex containing bridging bis(nicotinate)-polyethylene glycol ester ligand on differentiation pathways of murine Th lymphocytes activated by T cell mitogen.
P2860
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P2860
Metal-drug synergy: new ruthenium(II) complexes of ketoconazole are highly active against Leishmania major and Trypanosoma cruzi and nontoxic to human or murine normal cells
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 24 July 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Metal-drug synergy: new ruthenium
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Metal-drug synergy: new ruthen ...... o human or murine normal cells
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type
label
Metal-drug synergy: new ruthenium
@nl
Metal-drug synergy: new ruthen ...... o human or murine normal cells
@en
prefLabel
Metal-drug synergy: new ruthenium
@nl
Metal-drug synergy: new ruthen ...... o human or murine normal cells
@en
P2093
P2860
P1476
Metal-drug synergy: new ruthen ...... o human or murine normal cells
@en
P2093
Aaron Sattler
Alberto Martínez
Antonio Sánchez
Eva Iniguez
Joanna Olivas
Miguel A Vasquez
Roberto A Sánchez-Delgado
Rosa A Maldonado
P2860
P2888
P304
P356
10.1007/S00775-013-1024-2
P577
2013-07-24T00:00:00Z