Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency. - Wikidata - awgldk - TriplyDB

Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

http://www.wikidata.org/entity/Q34154888

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NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest Impact of IL28B, ITPA and PNPLA3 genetic variants on therapeutic outcome and progression of hepatitis C virus infection The human ITPA polymorphic variant P32T is destabilized by the unpacking of the hydrophobic core A disease spectrum for ITPA variation: advances in biochemical and clinical research Pharmacogenomics and personalized medicine: a review focused on their application in the Chinese population NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals ITPA Polymorphisms Are Associated with Hematological Side Effects during Antiviral Therapy for Chronic HCV Infection GLiMMPS: robust statistical model for regulatory variation of alternative splicing using RNA-seq data.Pharmacogenomic studies of the anticancer and immunosuppressive thiopurines mercaptopurine and azathioprine Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients.Variants of the inosine triphosphate pyrophosphatase gene are associated with reduced relapse risk following treatment for HCV genotype 2/3.Association between IPTA gene polymorphisms and hematological abnormalities in hepatitis C virus-infected patients receiving combination therapy.Erythrocyte inosine triphosphatase activity is decreased in HIV-seropositive individuals.Association of ITPA genotype with event-free survival and relapse rates in children with acute lymphoblastic leukemia undergoing maintenance therapy Mutation in the ITPA gene predicts intolerance to azathioprine.Allele frequency of inosine triphosphate pyrophosphatase gene polymorphisms in a Japanese population.Crystal structure of human inosine triphosphatase. Substrate binding and implication of the inosine triphosphatase deficiency mutation P32T.Determinants of mercaptopurine toxicity in paediatric acute lymphoblastic leukemia maintenance therapy Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia and decrease the need for ribavirin dose reduction Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia in HIV/HCV-coinfected patients with all HCV genotypes A Prospective Study Evaluating Metabolic Capacity of Thiopurine and Associated Adverse Reactions in Japanese Patients with Inflammatory Bowel Disease (IBD).Role of genetic polymorphisms in hepatitis C virus chronic infection.Pharmacogenomics and IBD: TPMT and thiopurines.Relationship between ITPA polymorphisms and hemolytic anemia in HCV-infected patients after ribavirin-based therapy: a meta-analysis Identification of ITPA on chromosome 20 as a susceptibility gene for young-onset tuberculosis.Neuronal deficiency of ARV1 causes an autosomal recessive epileptic encephalopathy.Inosine triphosphatase allele frequency and association with ribavirin-induced anaemia in Brazilian patients receiving antiviral therapy for chronic hepatitis C ITPA gene polymorphisms significantly affect hemoglobin decline and treatment outcomes in patients coinfected with HIV and HCV.Short interferon and ribavirin treatment for HCV genotype 2 or 3 infection: NORDynamIC trial and real-life experience.Review article: thiopurines in inflammatory bowel disease.Modeling Ribavirin-Induced Anemia in Patients with Chronic Hepatitis C Virus Clinical application of pharmacogenetics in gastrointestinal diseases.Review article: interactions between genotype and response to therapy in inflammatory bowel diseases.The ITPA and C20orf194 Polymorphisms and Hematological Changes During Treatment With Pegylated-Interferon Plus Ribavirin in Patients With Chronic Hepatitis C.Pharmacogenetic significance of inosine triphosphatase.Inosine triphosphatase genetic variants are protective against anemia during antiviral therapy for HCV2/3 but do not decrease dose reductions of RBV or increase SVR.Association of ITPA polymorphism with outcomes of peginterferon-α plus ribavirin combination therapy.Inosine triphosphate pyrophosphohydrolase (ITPA) polymorphic sequence variants in adult hematological malignancy patients and possible association with mitochondrial DNA defects Pharmacogenetics of Crohn's disease.Deoxyinosine triphosphate induces MLH1/PMS2- and p53-dependent cell growth arrest and DNA instability in mammalian cells

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P2860

Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

http://www.wikidata.org/entity/Q34154888

description

2002 nî lūn-bûn

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2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2002 թվականի օգոստոսին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

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Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

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Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

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type

label

Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

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Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

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Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

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Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

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Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

@en

Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

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Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency

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Anthony M Marinaki

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Azhar Ansari

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H Anne Simmonds

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Jeremy Sanderson

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John A Duley

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Lynette Fairbanks

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