about
The human ITPA polymorphic variant P32T is destabilized by the unpacking of the hydrophobic coreA disease spectrum for ITPA variation: advances in biochemical and clinical researchPharmacogenomics and personalized medicine: a review focused on their application in the Chinese populationGene expression and thiopurine metabolite profiling in inflammatory bowel disease - novel clues to drug targets and disease mechanisms?Variants of the inosine triphosphate pyrophosphatase gene are associated with reduced relapse risk following treatment for HCV genotype 2/3.Association between IPTA gene polymorphisms and hematological abnormalities in hepatitis C virus-infected patients receiving combination therapy.Role of ITPA gene polymorphism in ribavirin-induced anemia and thrombocytopenia in Egyptian patients with chronic hepatitis C.Erythrocyte inosine triphosphatase activity is decreased in HIV-seropositive individuals.Pivotal role of inosine triphosphate pyrophosphatase in maintaining genome stability and the prevention of apoptosis in human cells.Clinical utility of pharmacogenomics in the management of hepatitis C.Consensus and conflict cards for metabolic pathway databases.Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia and decrease the need for ribavirin dose reductionVariants in the ITPA gene protect against ribavirin-induced hemolytic anemia in HIV/HCV-coinfected patients with all HCV genotypesApoptosome activation, an important molecular instigator in 6-mercaptopurine induced Leydig cell death.Several factors including ITPA polymorphism influence ribavirin-induced anemia in chronic hepatitis C.The impact of inosine triphosphatase variants on hemoglobin level and sustained virologic response of chronic hepatitis C in Korean.Inosine triphosphate pyrophosphohydrolase (ITPA) polymorphic sequence variants in adult hematological malignancy patients and possible association with mitochondrial DNA defectsITPA (inosine triphosphate pyrophosphatase): from surveillance of nucleotide pools to human disease and pharmacogeneticsGenetic polymorphism of inosine triphosphate pyrophosphatase is a determinant of mercaptopurine metabolism and toxicity during treatment for acute lymphoblastic leukemia.Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools.Genetic polymorphism of inosine-triphosphate-pyrophosphatase influences mercaptopurine metabolism and toxicity during treatment of acute lymphoblastic leukemia individualized for thiopurine-S-methyl-transferase status.Pharmacogenomics in the treatment of inflammatory bowel disease.Inosine triphosphate pyrophosphatase 94C>A polymorphism: clinical implications for patients with systemic lupus erythematosus treated with azathioprine.Translating pharmacogenetics into clinical practice: interleukin (IL)28B and inosine triphosphatase (ITPA) polymophisms in hepatitis C virus (HCV) infection.The relationship between ITPA rs1127354 polymorphisms and efficacy of antiviral treatment in Northeast Chinese CHC patients.Pharmacogenetics of ribavirin-induced anemia in HCV patients.Quantitative in vitro and in vivo characterization of the human P32T mutant ITPase.Distribution of genetic polymorphisms associated with hepatitis C virus (HCV) antiviral response in a multiethnic and admixed population.Gene polymorphisms involved in manifestation of leucopenia, digestive intolerance, and pancreatitis in azathioprine-treated patients.Do variations in the ITPA gene determine the risk of hepatitis C virus relapse?A novel multiparameter flow cytometric assay for inosine triphosphatase expression analysis in leukocytes.Classic Galactosemia: Study on the Late Prenatal Development of GALT Specific Activity in a Sheep Model.Inosine Triphosphate Pyrophosphatase Dephosphorylates Ribavirin Triphosphate and Reduced Enzymatic Activity Potentiates Mutagenesis in Hepatitis C VirusEvolving Trends in the Hepatitis C Virus Molecular Epidemiology Studies: From the Viral Sequences to the Human Genome
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Pharmacogenetic significance of inosine triphosphatase.
@en
type
label
Pharmacogenetic significance of inosine triphosphatase.
@en
prefLabel
Pharmacogenetic significance of inosine triphosphatase.
@en
P2093
P2860
P1433
P1476
Pharmacogenetic significance of inosine triphosphatase.
@en
P2093
Jaap A Bakker
Jörgen Bierau
Martijn Lindhout
P2860
P304
P356
10.2217/14622416.8.9.1221
P577
2007-09-01T00:00:00Z