Deciphering the interleukin 28B variants that better predict response to pegylated interferon-α and ribavirin therapy in HCV/HIV-1 coinfected patients
about
IFNL3 mRNA structure is remodeled by a functional non-coding polymorphism associated with hepatitis C virus clearanceRegulation of hepatic innate immunity by hepatitis C virusGenetic variants at the IFNL3 locus and their association with hepatitis C virus infections reveal novel insights into host-virus interactionsPrevalence of IFNL3 rs4803217 single nucleotide polymorphism and clinical course of chronic hepatitis C.The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced microRNAs.Selection on a variant associated with improved viral clearance drives local, adaptive pseudogenization of interferon lambda 4 (IFNL4)IFN-λ4: the paradoxical new member of the interferon lambda family.A single nucleotide polymorphism associated with hepatitis C virus infections located in the distal region of the IL28B promoter influences NF-κB-mediated gene transcriptionHost Genetic Factors and Dendritic Cell Responses Associated with the Outcome of Interferon/Ribavirin Treatment in HIV-1/HCV Co-Infected Individuals.Detection of allele specific differences in IFNL3 (IL28B) mRNA expressionFavourable IFNL3 genotypes are associated with spontaneous clearance and are differentially distributed in Aboriginals in Canadian HIV-hepatitis C co-infected individuals.Hepatitis C Virus. Strategies to Evade Antiviral ResponsesComparison of functional variants in IFNL4 and IFNL3 for association with HCV clearance.The impact of interferon lambda 3 gene polymorphism on natural course and treatment of hepatitis CPharmGKB summary: peginterferon-α pathway.Responder Interferon λ Genotypes Are Associated With Higher Risk of Liver Fibrosis in HIV-Hepatitis C Virus CoinfectionThe IFN-λ Genetic Polymorphism Association With the Viral Clearance Induced by Hepatitis C Virus Treatment in Pakistani Patients.IL28B polymorphisms as a pretreatment predictor of response to HCV treatment.The role of pharmacogenetics in the treatment of chronic hepatitis C infection.Insights into antiviral innate immunity revealed by studying hepatitis C virus.The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections.Hepatitis-C-virus-induced microRNAs dampen interferon-mediated antiviral signaling.IL28RA polymorphism is associated with early hepatitis C virus (HCV) treatment failure in human immunodeficiency virus-/HCV-coinfected patients.
P2860
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P2860
Deciphering the interleukin 28B variants that better predict response to pegylated interferon-α and ribavirin therapy in HCV/HIV-1 coinfected patients
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Deciphering the interleukin 28 ...... HCV/HIV-1 coinfected patients
@ast
Deciphering the interleukin 28 ...... HCV/HIV-1 coinfected patients
@en
Deciphering the interleukin 28 ...... HCV/HIV-1 coinfected patients
@nl
type
label
Deciphering the interleukin 28 ...... HCV/HIV-1 coinfected patients
@ast
Deciphering the interleukin 28 ...... HCV/HIV-1 coinfected patients
@en
Deciphering the interleukin 28 ...... HCV/HIV-1 coinfected patients
@nl
prefLabel
Deciphering the interleukin 28 ...... HCV/HIV-1 coinfected patients
@ast
Deciphering the interleukin 28 ...... HCV/HIV-1 coinfected patients
@en
Deciphering the interleukin 28 ...... HCV/HIV-1 coinfected patients
@nl
P2093
P2860
P1433
P1476
Deciphering the interleukin 28 ...... HCV/HIV-1 coinfected patients
@en
P2093
Cristina Tural
Ester Aparicio
Mariona Parera
Montserrat de Castellarnau
Sandra Franco
P2860
P304
P356
10.1371/JOURNAL.PONE.0031016
P407
P577
2012-02-06T00:00:00Z