The 3'-untranslated region of p21WAF1 mRNA is a composite cis-acting sequence bound by RNA-binding proteins from breast cancer cells, including HuR and poly(C)-binding protein.
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RNPC1, an RNA-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress-induced p21 transcriptRNA processing and modification protein, carbon catabolite repression 4 (Ccr4), arrests the cell cycle through p21-dependent and p53-independent pathwayLoss of the nuclear receptor corepressor SLIRP compromises male fertilityExamination of the expanding pathways for the regulation of p21 expression and activity.Current Evidence and Future Perspectives on HuR and Breast Cancer Development, Prognosis, and TreatmentThe cyclin-dependent kinase inhibitor p21 is regulated by RNA-binding protein PCBP4 via mRNA stabilityHADHB, HuR, and CP1 bind to the distal 3'-untranslated region of human renin mRNA and differentially modulate renin expressionMultiple functions of the RNA-binding protein HuR in cancer progression, treatment responses and prognosisRegulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7Posttranscriptional regulation of p53 and its targets by RNA-binding proteinsPoly C binding protein, a single-stranded DNA binding protein, regulates mouse mu-opioid receptor gene expressionRNPC1 modulates the RNA-binding activity of, and cooperates with, HuR to regulate p21 mRNA stability.Post-transcriptional regulation of the Brn-3b transcription factor in differentiating neuroblastoma cells.Grape seed extract upregulates p21 (Cip1) through redox-mediated activation of ERK1/2 and posttranscriptional regulation leading to cell cycle arrest in colon carcinoma HT29 cells.Control of mRNA stability by SAPKs.Incrimination of heterogeneous nuclear ribonucleoprotein E1 (hnRNP-E1) as a candidate sensor of physiological folate deficiency.The RNA-binding protein HuR opposes the repression of ERBB-2 gene expression by microRNA miR-331-3p in prostate cancer cellsEvidence for post-transcriptional regulation of Na,K-ATPase by prostaglandin E1.cAMP controls human renin mRNA stability via specific RNA-binding proteins.Influence of physiologic folate deficiency on human papillomavirus type 16 (HPV16)-harboring human keratinocytes in vitro and in vivo.HuR function in disease.Downregulated Poly-C binding protein-1 is a novel predictor associated with poor prognosis in Acute Myeloid Leukemia.Proliferative markers as prognostic and predictive tools in early breast cancer: where are we now?Interaction of RNA-binding proteins HuR and AUF1 with the human ATF3 mRNA 3'-untranslated region regulates its amino acid limitation-induced stabilization.mRNA stability control: a clandestine force in normal and malignant hematopoiesis.mRNA stability and cancer: an emerging link?Induction of p21(CIP1/WAF1) expression by human T-lymphotropic virus type 1 Tax requires transcriptional activation and mRNA stabilizationmiR-331-3p regulates ERBB-2 expression and androgen receptor signaling in prostate cancerPhosphorylation of poly(rC) binding protein 1 (PCBP1) contributes to stabilization of mu opioid receptor (MOR) mRNA via interaction with AU-rich element RNA-binding protein 1 (AUF1) and poly A binding protein (PABP).HuR silencing elicits oxidative stress and DNA damage and sensitizes human triple-negative breast cancer cells to radiotherapy.The role of the 3' untranslated region in post-transcriptional regulation of protein expression in mammalian cells.Post-transcriptional regulation of DNA damage-responsive gene expressionEvidence Favoring a Positive Feedback Loop for Physiologic Auto Upregulation of hnRNP-E1 during Prolonged Folate Deficiency in Human Placental Cells.mRNA openers and closers: modulating AU-rich element-controlled mRNA stability by a molecular switch in mRNA secondary structure.Poly(C)-binding protein 1 (Pcbp1) regulates skeletal muscle differentiation by modulating microRNA processing in myoblasts.A cis-acting region in the N-methyl-d-aspartate R1 3'-untranslated region interacts with the novel RNA-binding proteins beta subunit of alpha glucosidase II and annexin A2--effect of chronic ethanol exposure in vivo.Regulation of Human PAX6 Expression by miR-7.MDM2 expression is repressed by the RNA-binding protein RNPC1 via mRNA stability.Sequence requirements for RNA binding by HuR and AUF1.Depletion of the poly(C)-binding proteins alphaCP1 and alphaCP2 from K562 cells leads to p53-independent induction of cyclin-dependent kinase inhibitor (CDKN1A) and G1 arrest.
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P2860
The 3'-untranslated region of p21WAF1 mRNA is a composite cis-acting sequence bound by RNA-binding proteins from breast cancer cells, including HuR and poly(C)-binding protein.
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
The 3'-untranslated region of ...... R and poly(C)-binding protein.
@ast
The 3'-untranslated region of ...... R and poly(C)-binding protein.
@en
The 3'-untranslated region of ...... R and poly(C)-binding protein.
@nl
type
label
The 3'-untranslated region of ...... R and poly(C)-binding protein.
@ast
The 3'-untranslated region of ...... R and poly(C)-binding protein.
@en
The 3'-untranslated region of ...... R and poly(C)-binding protein.
@nl
prefLabel
The 3'-untranslated region of ...... R and poly(C)-binding protein.
@ast
The 3'-untranslated region of ...... R and poly(C)-binding protein.
@en
The 3'-untranslated region of ...... R and poly(C)-binding protein.
@nl
P2093
P2860
P356
P1476
The 3'-untranslated region of ...... R and poly(C)-binding protein.
@en
P2093
Andrew M Thomson
Dianne J Beveridge
Dominic C Voon
Henry M Furneaux
Jalal A Jazayeri
John M Daly
Keith M Giles
Peter J Leedman
P2860
P304
P356
10.1074/JBC.M208439200
P407
P577
2002-11-12T00:00:00Z