BRAF mutation is rare in advanced-stage low-grade ovarian serous carcinomas.
about
Better therapeutic trials in ovarian cancer.KRAS, BRAF genotyping reveals genetic heterogeneity of ovarian borderline tumors and associated implants.Whole exome sequence analysis of serous borderline tumors of the ovary.KRAS (but not BRAF) mutations in ovarian serous borderline tumour are associated with recurrent low-grade serous carcinomaThe H3K9 methyltransferase G9a is a marker of aggressive ovarian cancer that promotes peritoneal metastasis.The anterior gradient homolog 3 (AGR3) gene is associated with differentiation and survival in ovarian cancerBRAF mutation is associated with a specific cell type with features suggestive of senescence in ovarian serous borderline (atypical proliferative) tumorsIntratumoral heterogeneity in a minority of ovarian low-grade serous carcinomasMicroenvironment and pathogenesis of epithelial ovarian cancerHormonal therapy for recurrent low-grade serous carcinoma of the ovary or peritoneum.Molecular approaches to personalizing management of ovarian cancer.BRAF gene: From human cancers to developmental syndromes.Wild-type tumor repressor protein 53 (Trp53) promotes ovarian cancer cell survival.Minireview: animal models and mechanisms of ovarian cancer development.Impact of Age and Primary Disease Site on Outcome in Women With Low-Grade Serous Carcinoma of the Ovary or Peritoneum: Results of a Large Single-Institution Registry of a Rare Tumor.Extreme Outlier Analysis Identifies Occult Mitogen-Activated Protein Kinase Pathway Mutations in Patients With Low-Grade Serous Ovarian Cancer.Low-grade serous carcinomas of the ovary contain very few point mutationsMolecular profiling of low grade serous ovarian tumours identifies novel candidate driver genes.P53, MAPK, topoisomerase II alpha and Ki67 immunohistochemical expression and KRAS/BRAF mutation in ovarian serous carcinomas.Rational selection of biomarker driven therapies for gynecologic cancers: The more we know, the more we know we don't knowImpact of mutational status on survival in low-grade serous carcinoma of the ovary or peritoneum.Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: an open-label, single-arm, phase 2 study.The molecular pathology of ovarian serous borderline tumors.A long-term surviving patient with recurrent low-grade serous ovarian carcinoma treated with the MEK1/2 inhibitor, selumetinib.The status of epidermal growth factor receptor in borderline ovarian tumours.Origin of ovarian cancer: molecular profilingGenetic and molecular changes in ovarian cancer.New hypothesis on pathogenesis of ovarian cancer lead to future tailored approaches.Clinical implications of using molecular diagnostics for ovarian cancers.Differences in MEK inhibitor efficacy in molecularly characterized low-grade serous ovarian cancer cell lines.BRAF mutation is associated with early stage disease and improved outcome in patients with low-grade serous ovarian cancer.BRAF mutation testing in clinical practice.Molecular abnormalities in ovarian carcinoma: clinical, morphological and therapeutic correlates.The diagnostic utility of TP53 and CDKN2A to distinguish ovarian high-grade serous carcinoma from low-grade serous ovarian tumors.Impact of lympho-vascular space invasion on tumor characteristics and survival outcome of women with low-grade serous ovarian carcinoma.Targeted agents and combinations in ovarian cancer: where are we now?The Dualistic Model of Ovarian Carcinogenesis: Revisited, Revised, and Expanded.Sustained response to vemurafenib in a low grade serous ovarian cancer with a BRAF V600E mutation.Mutation of NRAS is a Rare Genetic Event in Ovarian Low-Grade Serous Carcinoma.CD73s protection of epithelial integrity: Thinking beyond the barrier.
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P2860
BRAF mutation is rare in advanced-stage low-grade ovarian serous carcinomas.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
BRAF mutation is rare in advanced-stage low-grade ovarian serous carcinomas.
@ast
BRAF mutation is rare in advanced-stage low-grade ovarian serous carcinomas.
@en
BRAF mutation is rare in advanced-stage low-grade ovarian serous carcinomas.
@nl
type
label
BRAF mutation is rare in advanced-stage low-grade ovarian serous carcinomas.
@ast
BRAF mutation is rare in advanced-stage low-grade ovarian serous carcinomas.
@en
BRAF mutation is rare in advanced-stage low-grade ovarian serous carcinomas.
@nl
prefLabel
BRAF mutation is rare in advanced-stage low-grade ovarian serous carcinomas.
@ast
BRAF mutation is rare in advanced-stage low-grade ovarian serous carcinomas.
@en
BRAF mutation is rare in advanced-stage low-grade ovarian serous carcinomas.
@nl
P2093
P2860
P1476
BRAF mutation is rare in advanced-stage low-grade ovarian serous carcinomas.
@en
P2093
Charlotte Sun
David M Gershenson
Judith K Wolf
Karen H Lu
Kwong-Kwok Wong
Michael T Deavers
Samuel C Mok
Yvonne T M Tsang
P2860
P304
P356
10.2353/AJPATH.2010.100212
P407
P577
2010-08-27T00:00:00Z