Age-related dysregulation of CD8+ T cell memory specific for a persistent virus is independent of viral replication
about
T cell memory in the context of persistent herpes viral infectionsEarly priming minimizes the age-related immune compromise of CD8⁺ T cell diversity and functionSustained CD8+ T cell memory inflation after infection with a single-cycle cytomegalovirus.Translational research in immune senescence: assessing the relevance of current models.Altered T cell memory and effector cell development in chronic lymphatic filarial infection that is independent of persistent parasite antigen.Functional CD8 T cell memory responding to persistent latent infection is maintained for life.Nonmalignant clonal expansions of memory CD8+ T cells that arise with age vary in their capacity to mount recall responses to infection.Diversity of the CD8+ T cell repertoire elicited against an immunodominant epitope does not depend on the context of infection.Inflation and long-term maintenance of CD8 T cells responding to a latent herpesvirus depend upon establishment of latency and presence of viral antigens.Acute neonatal infections 'lock-in' a suboptimal CD8+ T cell repertoire with impaired recall responses.Lifelong persistent viral infection alters the naive T cell pool, impairing CD8 T cell immunity in late life.Immunity, ageing and cancer.Early childhood stress is associated with elevated antibody levels to herpes simplex virus type 1.Inhibition of transplantation tolerance by immune senescence is reversed by endocrine modulationAgeing and life-long maintenance of T-cell subsets in the face of latent persistent infectionsCytomegalovirus and human immunosenescence.Factors that may impact on immunosenescence: an appraisal.
P2860
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P2860
Age-related dysregulation of CD8+ T cell memory specific for a persistent virus is independent of viral replication
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Age-related dysregulation of C ...... dependent of viral replication
@ast
Age-related dysregulation of C ...... dependent of viral replication
@en
Age-related dysregulation of C ...... dependent of viral replication
@nl
type
label
Age-related dysregulation of C ...... dependent of viral replication
@ast
Age-related dysregulation of C ...... dependent of viral replication
@en
Age-related dysregulation of C ...... dependent of viral replication
@nl
prefLabel
Age-related dysregulation of C ...... dependent of viral replication
@ast
Age-related dysregulation of C ...... dependent of viral replication
@en
Age-related dysregulation of C ...... dependent of viral replication
@nl
P2093
P2860
P1476
Age-related dysregulation of C ...... dependent of viral replication
@en
P2093
Ilhem Messaoudi
James D Brien
P2860
P304
P356
10.4049/JIMMUNOL.180.7.4848
P407
P577
2008-04-01T00:00:00Z