The telomerase RNA component Terc is required for the tumour-promoting effects of Tert overexpression.
about
Telomeres in aging and disease: lessons from zebrafishWRAP53 promotes cancer cell survival and is a potential target for cancer therapy.TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental programBehaviour of telomere and telomerase during aging and regeneration in zebrafish.Telomerase can act as a template- and RNA-independent terminal transferase.Human telomerase catalytic subunit (hTERT) suppresses p53-mediated anti-apoptotic response via induction of basic fibroblast growth factor.The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidenceThe telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in miceTelomeres and aging.Bone marrow skeletal stem/progenitor cell defects in dyskeratosis congenita and telomere biology disorders.Genetic analysis of myc and telomerase interactions in vivo.Telomere dysfunction promotes metastasis in a TERC null mouse model of head and neck cancer.PinX1: a sought-after major tumor suppressor at human chromosome 8p23A virus-encoded telomerase RNA promotes malignant T cell lymphomagenesis.Genomic amplification of the human telomerase gene (hTERC) associated with human papillomavirus is related to the progression of uterine cervical dysplasia to invasive cancer.Role for telomerase in pulmonary hypertensionCell-cycle-dependent telomere elongation by telomerase in budding yeast.Non-telomeric activities of telomerase.Telomerase and its extracurricular activities.Involvement of the oncoprotein c-Myc in viral telomerase RNA gene regulation during Marek's disease virus-induced lymphomagenesis.No attenuation of the ATM-dependent DNA damage response in murine telomerase-deficient cells.MYC drives overexpression of telomerase RNA (hTR/TERC) in prostate cancer.A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish.Expression of targeted ribozyme against telomerase RNA causes altered expression of several other genes in tumor cells.
P2860
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P2860
The telomerase RNA component Terc is required for the tumour-promoting effects of Tert overexpression.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The telomerase RNA component T ...... ffects of Tert overexpression.
@ast
The telomerase RNA component T ...... ffects of Tert overexpression.
@en
The telomerase RNA component T ...... ffects of Tert overexpression.
@nl
type
label
The telomerase RNA component T ...... ffects of Tert overexpression.
@ast
The telomerase RNA component T ...... ffects of Tert overexpression.
@en
The telomerase RNA component T ...... ffects of Tert overexpression.
@nl
prefLabel
The telomerase RNA component T ...... ffects of Tert overexpression.
@ast
The telomerase RNA component T ...... ffects of Tert overexpression.
@en
The telomerase RNA component T ...... ffects of Tert overexpression.
@nl
P2860
P356
P1433
P1476
The telomerase RNA component T ...... ffects of Tert overexpression.
@en
P2093
Juana M Flores
María Luisa Cayuela
P2860
P304
P356
10.1038/SJ.EMBOR.7400359
P577
2005-03-01T00:00:00Z