Constitutive telomerase expression promotes mammary carcinomas in aging mice. - Wikidata - awgldk - TriplyDB

Constitutive telomerase expression promotes mammary carcinomas in aging mice.

Constitutive telomerase expression promotes mammary carcinomas in aging mice.

http://www.wikidata.org/entity/Q34031827

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Shortened telomere length is associated with increased risk of cancer: a meta-analysis Telomerase modulates Wnt signalling by association with target gene chromatin Telomerase reverse transcriptase regulates microRNAs An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA Deletion of the telomerase reverse transcriptase gene and haploinsufficiency of telomere maintenance in Cri du chat syndrome Identification of PITX1 as a TERT suppressor gene located on human chromosome 5 Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer Complex roles for telomeres and telomerase in breast carcinogenesis Models of breast cancer: quo vadis, animal modeling?A balanced transcription between telomerase and the telomeric DNA-binding proteins TRF1, TRF2 and Pot1 in resting, activated, HTLV-1-transformed and Tax-expressing human T lymphocytes Telomeres in aging and disease: lessons from zebrafish Reactivation of telomerase in cancer InTERTesting association between telomerase, mTOR and phytochemicals Telomere shortening sensitizes cancer cells to selected cytotoxic agents: in vitro and in vivo studies and putative mechanisms Conditional telomerase induction causes proliferation of hair follicle stem cells Telomeres and telomerase in head and neck squamous cell carcinoma: from pathogenesis to clinical implications.HPV16 E7 protein and hTERT proteins defective for telomere maintenance cooperate to immortalize human keratinocytes Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging.Parents' ages at birth and risk of adult-onset hematologic malignancies among female teachers in California A Cajal body-independent pathway for telomerase trafficking in mice.Stem cell aging: mechanisms, regulators and therapeutic opportunities.The telomerase RNA component Terc is required for the tumour-promoting effects of Tert overexpression.The role of telomeres and telomerase in cancer research.Telomere-based crisis: functional differences between telomerase activation and ALT in tumor progression Genetic variants in telomere-maintenance genes and bladder cancer risk.The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in mice Regulation of the human catalytic subunit of telomerase (hTERT).Telomerase extracurricular activities.Telomere fusions in early human breast carcinoma.Neil3 and NEIL1 DNA glycosylases remove oxidative damages from quadruplex DNA and exhibit preferences for lesions in the telomeric sequence context.The aging lacrimal gland: changes in structure and function.Bladder cancer in the elderly.Regulation of senescence in cancer and aging.Telomeres and aging.Telomerase activity and genetic alterations in primary breast carcinomas.Cytogenetic characterization and H-ras associated transformation of immortalized human mammary epithelial cells.Branched-chain amino acids enhance premature senescence through mammalian target of rapamycin complex I-mediated upregulation of p21 protein.The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structures Telomere length variation: A potential new telomere biomarker for lung cancer risk.

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P2860

Constitutive telomerase expression promotes mammary carcinomas in aging mice.

http://www.wikidata.org/entity/Q34031827

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2002 nî lūn-bûn

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2002 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Constitutive telomerase expression promotes mammary carcinomas in aging mice.

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Constitutive telomerase expression promotes mammary carcinomas in aging mice.

@en

Constitutive telomerase expression promotes mammary carcinomas in aging mice.

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type

label

Constitutive telomerase expression promotes mammary carcinomas in aging mice.

@ast

Constitutive telomerase expression promotes mammary carcinomas in aging mice.

@en

Constitutive telomerase expression promotes mammary carcinomas in aging mice.

@nl

prefLabel

Constitutive telomerase expression promotes mammary carcinomas in aging mice.

@ast

Constitutive telomerase expression promotes mammary carcinomas in aging mice.

@en

Constitutive telomerase expression promotes mammary carcinomas in aging mice.

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Proceedings of the National Academy of Sciences of the United States of America

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Constitutive telomerase expression promotes mammary carcinomas in aging mice.

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Diego H Castrillon

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James W Horner

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Maja K Tietze

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Roger A Greenberg

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Ronald A DePinho

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Ruben D Carrasco

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Sarah R Weiler

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Scott Alson

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Siqin Ye

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Steven E Artandi

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P2860

Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

Specific association of human telomerase activity with immortal cells and cancer

Efficient selection for high-expression transfectants with a novel eukaryotic vector

Creation of human tumour cells with defined genetic elements

The RNA component of human telomerase

Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes.

Telomere dysfunction and evolution of intestinal carcinoma in mice and humans

The serial cultivation of human diploid cell strains

Telomeres shorten during ageing of human fibroblasts

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8191-8196

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10.1073/PNAS.112515399

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12

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99

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Norman Sharpless

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2002-05-28T00:00:00Z

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11337497

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12034875

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123043

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