2-methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway.
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Thrombospondin-1-induced apoptosis of brain microvascular endothelial cells can be mediated by TNF-R1Recent translational research: antiangiogenic therapy for breast cancer - where do we stand?Opposite regulation of XIAP and Smac/DIABLO in the rat endometrium in response to 17beta-estradiol at estrusMaspin overexpression modulates tumor cell apoptosis through the regulation of Bcl-2 family proteinsNitric oxide-mediated sensitization of resistant tumor cells to apoptosis by chemo-immunotherapeuticsRNA-dependent protein kinase is essential for 2-methoxyestradiol-induced autophagy in osteosarcoma cellsDisease modifying and antiangiogenic activity of 2-methoxyestradiol in a murine model of rheumatoid arthritis.2-Methoxyestradiol ameliorates glucose tolerance with the increase in β-cell mass in db/db mice.An estrogen analogue and promising anticancer agent refrains from inducing morphological damage and reactive oxygen species generation in erythrocytes, fibrin and platelets: a pilot studyPhase I trial of 2-methoxyestradiol NanoCrystal dispersion in advanced solid malignancies.PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple myeloma cellsA phase II study of 2-methoxyestradiol (2ME2) NanoCrystal® dispersion (NCD) in patients with taxane-refractory, metastatic castrate-resistant prostate cancer (CRPC).Combination of albendazole and 2-methoxyestradiol significantly improves the survival of HCT-116 tumor-bearing nude mice.Effects of hormone deprivation and 2-methoxyestradiol combination therapy on hormone-dependent prostate cancer in vivo.A low COMT activity haplotype is associated with recurrent preeclampsia in a Norwegian population cohort (HUNT2)A phase I dose-escalation, safety and pharmacokinetic study of the 2-methoxyestradiol analog ENMD-1198 administered orally to patients with advanced cancer.Chaetoglobosin K induces apoptosis and G2 cell cycle arrest through p53-dependent pathway in cisplatin-resistant ovarian cancer cellsEstrogens and prostate cancer: etiology, mediators, prevention, and management.Antiproliferative activity of Vallaris glabra Kuntze (Apocynaceae)A phase II study of 2-methoxyestradiol nanocrystal colloidal dispersion alone and in combination with sunitinib malate in patients with metastatic renal cell carcinoma progressing on sunitinib malate.A molecular understanding of D-homoestrone-induced G2/M cell cycle arrest in HeLa human cervical carcinoma cellsPharmacokinetics and efficacy of 2-methoxyoestradiol and 2-methoxyoestradiol-bis-sulphamate in vivo in rodents.Molecular crosstalk between apoptosis and autophagy induced by a novel 2-methoxyestradiol analogue in cervical adenocarcinoma cells.Potential vascular actions of 2-methoxyestradiolIn vitro assessment of a computer-designed potential anticancer agent in cervical cancer cells.Decursin enhances TRAIL-induced apoptosis through oxidative stress mediated- endoplasmic reticulum stress signalling in non-small cell lung cancersNovel combination of 2-methoxyestradiol and cyclophosphamide enhances the antineoplastic and pro-apoptotic effects on S-180 ascitic tumour cells.Valosin-containing Protein is a Target of 5'-l Fuligocandin B and Enhances TRAIL Resistance in Cancer Cells.The oestrogen metabolite 2-methoxyoestradiol alone or in combination with tumour necrosis factor-related apoptosis-inducing ligand mediates apoptosis in cancerous but not healthy cells of the human endometrium.The role of osteoprotegerin and tumor necrosis factor-related apoptosis-inducing ligand in human microvascular endothelial cell survival.2-Methoxyestradiol exhibits a biphasic effect on VEGF-A in tumor cells and upregulation is mediated through ER-alpha: a possible signaling pathway associated with the impact of 2-ME2 on proliferative cells.Effect of 2-methoxyestradiol on SK-LMS-1 uterine leiomyosarcoma cells.Pregnenolone, a cholesterol metabolite, induces glioma cell apoptosis via activating extrinsic and intrinsic apoptotic pathwaysThe in vitro effects of a novel estradiol analog on cell proliferation and morphology in human epithelial cervical carcinoma.Kaempferol Induces G2/M Cell Cycle Arrest via Checkpoint Kinase 2 and Promotes Apoptosis via Death Receptors in Human Ovarian Carcinoma A2780/CP70 Cells.
P2860
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P2860
2-methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway.
description
2003 nî lūn-bûn
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2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
2-methoxyestradiol up-regulate ...... tion of the extrinsic pathway.
@ast
2-methoxyestradiol up-regulate ...... tion of the extrinsic pathway.
@en
2-methoxyestradiol up-regulate ...... tion of the extrinsic pathway.
@nl
type
label
2-methoxyestradiol up-regulate ...... tion of the extrinsic pathway.
@ast
2-methoxyestradiol up-regulate ...... tion of the extrinsic pathway.
@en
2-methoxyestradiol up-regulate ...... tion of the extrinsic pathway.
@nl
prefLabel
2-methoxyestradiol up-regulate ...... tion of the extrinsic pathway.
@ast
2-methoxyestradiol up-regulate ...... tion of the extrinsic pathway.
@en
2-methoxyestradiol up-regulate ...... tion of the extrinsic pathway.
@nl
P2093
P1433
P1476
2-methoxyestradiol up-regulate ...... tion of the extrinsic pathway.
@en
P2093
Chris J Herbstritt
Glenn Swartz
Mark S Williams
Michelle S Johnson
Shawn J Green
Theresa M LaVallee
Victor S Pribluda
Wendy A Hembrough
Xiaoguo H Zhan
P304
P407
P577
2003-01-01T00:00:00Z