2-methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway. - Wikidata - awgldk - TriplyDB

2-methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway.

2-methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway.

http://www.wikidata.org/entity/Q34172396

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Thrombospondin-1-induced apoptosis of brain microvascular endothelial cells can be mediated by TNF-R1 Recent translational research: antiangiogenic therapy for breast cancer - where do we stand?Opposite regulation of XIAP and Smac/DIABLO in the rat endometrium in response to 17beta-estradiol at estrus Maspin overexpression modulates tumor cell apoptosis through the regulation of Bcl-2 family proteins Nitric oxide-mediated sensitization of resistant tumor cells to apoptosis by chemo-immunotherapeutics RNA-dependent protein kinase is essential for 2-methoxyestradiol-induced autophagy in osteosarcoma cells Disease modifying and antiangiogenic activity of 2-methoxyestradiol in a murine model of rheumatoid arthritis.2-Methoxyestradiol ameliorates glucose tolerance with the increase in β-cell mass in db/db mice.An estrogen analogue and promising anticancer agent refrains from inducing morphological damage and reactive oxygen species generation in erythrocytes, fibrin and platelets: a pilot study Phase I trial of 2-methoxyestradiol NanoCrystal dispersion in advanced solid malignancies.PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple myeloma cells A phase II study of 2-methoxyestradiol (2ME2) NanoCrystal® dispersion (NCD) in patients with taxane-refractory, metastatic castrate-resistant prostate cancer (CRPC).Combination of albendazole and 2-methoxyestradiol significantly improves the survival of HCT-116 tumor-bearing nude mice.Effects of hormone deprivation and 2-methoxyestradiol combination therapy on hormone-dependent prostate cancer in vivo.A low COMT activity haplotype is associated with recurrent preeclampsia in a Norwegian population cohort (HUNT2)A phase I dose-escalation, safety and pharmacokinetic study of the 2-methoxyestradiol analog ENMD-1198 administered orally to patients with advanced cancer.Chaetoglobosin K induces apoptosis and G2 cell cycle arrest through p53-dependent pathway in cisplatin-resistant ovarian cancer cells Estrogens and prostate cancer: etiology, mediators, prevention, and management.Antiproliferative activity of Vallaris glabra Kuntze (Apocynaceae)A phase II study of 2-methoxyestradiol nanocrystal colloidal dispersion alone and in combination with sunitinib malate in patients with metastatic renal cell carcinoma progressing on sunitinib malate.A molecular understanding of D-homoestrone-induced G2/M cell cycle arrest in HeLa human cervical carcinoma cells Pharmacokinetics and efficacy of 2-methoxyoestradiol and 2-methoxyoestradiol-bis-sulphamate in vivo in rodents.Molecular crosstalk between apoptosis and autophagy induced by a novel 2-methoxyestradiol analogue in cervical adenocarcinoma cells.Potential vascular actions of 2-methoxyestradiol In vitro assessment of a computer-designed potential anticancer agent in cervical cancer cells.Decursin enhances TRAIL-induced apoptosis through oxidative stress mediated- endoplasmic reticulum stress signalling in non-small cell lung cancers Novel combination of 2-methoxyestradiol and cyclophosphamide enhances the antineoplastic and pro-apoptotic effects on S-180 ascitic tumour cells.Valosin-containing Protein is a Target of 5'-l Fuligocandin B and Enhances TRAIL Resistance in Cancer Cells.The oestrogen metabolite 2-methoxyoestradiol alone or in combination with tumour necrosis factor-related apoptosis-inducing ligand mediates apoptosis in cancerous but not healthy cells of the human endometrium.The role of osteoprotegerin and tumor necrosis factor-related apoptosis-inducing ligand in human microvascular endothelial cell survival.2-Methoxyestradiol exhibits a biphasic effect on VEGF-A in tumor cells and upregulation is mediated through ER-alpha: a possible signaling pathway associated with the impact of 2-ME2 on proliferative cells.Effect of 2-methoxyestradiol on SK-LMS-1 uterine leiomyosarcoma cells.Pregnenolone, a cholesterol metabolite, induces glioma cell apoptosis via activating extrinsic and intrinsic apoptotic pathways The in vitro effects of a novel estradiol analog on cell proliferation and morphology in human epithelial cervical carcinoma.Kaempferol Induces G2/M Cell Cycle Arrest via Checkpoint Kinase 2 and Promotes Apoptosis via Death Receptors in Human Ovarian Carcinoma A2780/CP70 Cells.

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P2860

2-methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway.

http://www.wikidata.org/entity/Q34172396

description

2003 nî lūn-bûn

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2003 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2003 թվականի հունվարին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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2-methoxyestradiol up-regulate ...... tion of the extrinsic pathway.

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Chris J Herbstritt

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Glenn Swartz

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Mark S Williams

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Shawn J Green

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2-methoxyestradiol